scholarly journals Changes in Anterior Segment Morphology of Iris Bombe before and after Laser Peripheral Iridotomy in Patients with Uveitic Secondary Glaucoma

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Wakako Ikegawa ◽  
Takashi Suzuki ◽  
Koji Namiguchi ◽  
Shiro Mizoue ◽  
Atsushi Shiraishi ◽  
...  
Keyword(s):  
Anterior Chamber ◽  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Anterior Chamber Angle ◽  
Laser Peripheral Iridotomy ◽  
Chamber Volume ◽  
Anterior Chamber Volume ◽  
Before And After ◽  
The Mean ◽  
Peripheral Iridotomy

Purpose. To quantify changes in anterior segment (AS) parameters after laser peripheral iridotomy (LPI) using AS-optical coherence tomography (OCT) of iris bombe. Method. AS images of eight eyes were captured before and after iris bombe and more than 2 weeks after LPI (post-LPI) using AS-OCT. We compared the following AS parameters: anterior chamber depth (ACD), anterior chamber volume (ACV), iris curvature (IC), iris thickness at 500 μm from the scleral spur (IT-1) in the middle between the iris root and pupillary margin (IT-2) and 500 μm from the pupillary margin (IT-3) to the anterior chamber angle (ACA) (angle opening distance [AOD750]), and trabecular iris space area. Results. Mean IT-1 and IT-3, but not IT-2, were lower after iris bombe (IT-1, P=0.001; IT-2, P=0.081; and IT-3, P=0.001). There were no significant differences between ACD at pre-LPI and before iris bombe (P=0.096). The mean ACV and AOD750 of iris bombe increased at post-LPI (ACV, P<0.01, and AOD750, P<0.05). The mean IT-1, IT-2, and IT-3 increased at post-LPI (all, P≤0.01). IC decreased at post-LPI (P<0.001), and ACD at post-LPI did not change. Conclusions. The iris extends and becomes thinner during iris bombe. LPI during bombe decreases the IC and increases the ACV and ACA.

scholarly journals Anterior Chamber Angle and Volume Do Not Change after Myopic Laser-Assisted In Situ Keratomileusis in Young Patients

2018 ◽  
Vol 2018 ◽  
pp. 1-4
Author(s):  
Ertuğrul Tan Yassa ◽  
Cihan Ünlü
Keyword(s):  
Anterior Chamber ◽  
Anterior Segment ◽  
Young Patients ◽  
Anterior Chamber Depth ◽  
Ablation Depth ◽  
Anterior Chamber Angle ◽  
Chamber Volume ◽  
The Mean ◽  
Chamber Angle

Purpose. We aimed to investigate whether anterior chamber angle, depth, and volume change after myopic laser-assisted in situ keratomileusis (LASIK) in young patients. Methods. This retrospective study included 29 eyes of 29 patients (15 females and 14 males) between the ages of 18 and 39 years who underwent LASIK for the treatment of myopia. In addition to complete ophthalmic examination, anterior chamber angle (ACA), central anterior chamber depth (ACD), and anterior chamber volume (ACV) were measured by using a Sirius rotating Scheimpflug camera combined with Placido disc corneal topography (CSO, Florence, Italy). Preoperative and postoperative values were compared using paired t-tests. Linear regression was used to evaluate the relationship between changes in refraction and changes in ACA, ACD, and ACV as well as between attempted maximum ablation depth and changes in ACA, ACD, and ACV. Results. The mean age of the study population was 25.5 ± 6.2 years. The mean preoperative and postoperative spherical equivalent values were −3.30 ± 1.92 D and −0.18 ± 0.29 D, respectively. ACV and ACA were not significantly changed after surgery; however, central ACD was significantly decreased (preoperatively = 3.366 ± 0.316 mm vs postoperatively = 3.3 ± 0.298 mm) with a mean difference of 0.066 ± 1.121 mm. There were no significant relationships between changes in refraction and anterior segment dimensions or between attempted maximum ablation depth and anterior segment dimensions. Conclusion. Measurements with Sirius showed that ACA and ACV did not change; however, central ACD significantly decreased after myopic LASIK in young patients, indicating that the preoperative central ACD value should not be used interchangeably with the postoperative central ACD value.

scholarly journals The effects of tolterodine on anterior segment and choroidal thickness in patients with overactive bladder syndrome

2017 ◽  
Vol 9 (5) ◽  
pp. 91-97 ◽  
Author(s):  
Hande Hüsniye Telek ◽  
Omer Gokhan Doluoglu ◽  
Ayse Burcu ◽  
Gulizar Demirok ◽  
Firdevs Ornek ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Anterior Chamber ◽  
Choroidal Thickness ◽  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Mean Value ◽  
Subfoveal Choroidal Thickness ◽  
Chamber Volume ◽  
Before And After ◽  
The Mean

Background: To evaluate the effects of tolterodine on anterior segment and choroidal thickness by using the Pentacam system and optical coherence tomography (OCT) (Pentacam). Methods: A total of 122 eyes of 61 patients (34 female; 27 male) were included in the study. All patients underwent a regular ocular examination and intraocular pressure measurements before and after 3 months of antimuscarinic drug tolterodine treatment, in addition, pupil diameter, anterior chamber depth, anterior chamber volume, anterior chamber angle, and lens thickness were measured through Pentacam (Oculus Inc., Wetzlar, Germany) system. Measurements of choroidal thickness were performed by OCT (Spectralis®, Heidelberg Engineering, Heidelberg, Germany). Results: The mean age was 58.4 ± 7.3 years and 56.5 ± 11.1 years for female and male patients. The mean intraocular pressure was 15.10 ± 2.75 mmHg before treatment and 15.18 ± 2.65 mmHg after treatment. Pupil diameters were 3.09 ± 0.48 mm before treatment and 3.12 ± 0.43 mm after treatment. Anterior chamber depth, before and after treatment were 2.68 ± 0.65 mm and 2.70 ± 0.61 mm. The mean value for subfoveal choroidal thickness was 267.92 ± 81.35 μm before the administration of tolterodine, whereas the mean choroidal thickness was 271.83 ± 75.42 μm after the administration of tolterodine. The alterations in the subfoveal choroidal thickness were not statistically significant ( p = 0.862). Conclusions: After 3 months of therapy with tolterodine, there were no significant changes in anterior segment parameters and choroidal thickness.

scholarly journals Effects of Laser Peripheral Iridotomy in Subgroups of Primary Angle Closure Based on Iris Insertion

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Sung-Cheol Yun ◽  
Ji Wook Hong ◽  
Kyung Rim Sung ◽  
Jin Young Lee
Keyword(s):  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Multivariate Regression Analysis ◽  
Angle Closure ◽  
Laser Peripheral Iridotomy ◽  
Factors Affecting ◽  
Primary Angle Closure ◽  
Before And After ◽  
Qualitative Classification ◽  
Peripheral Iridotomy

Purpose. To investigate the effect of laser peripheral iridotomy (LPI) in subgroups of primary angle closure based on iris insertion configuration.Methods. Anterior segment optical coherence tomography (AS-OCT) images were obtained before and two weeks after LPI. Qualitative classification of angle closure eyes according to iris insertion (basal insertion group (BG) and nonbasal insertion group (NBG)) was performed. Anterior chamber depth (ACD), lens vault (LV), iris curvature, iris area, iris thickness (IT750), and angle opening distance (AOD750) 750 microns from scleral spur were calculated. Uni- and multivariate regression analysis was carried out to evaluate factors associated with AOD750before and after LPI.Results. Ninety-two eyes of 92 subjects were categorized as NBG (39 eyes) or BG (53 eyes). The mean change after LPI was not significantly different between two groups in all parameters. In both groups, AOD750was affected by ACD (p<0.001,p=0.044) before LPI. AOD750was affected by LV (p=0.012) in NBG, but by ACD (p<0.001) and IT750(p=0.039) in BG after LPI.Conclusions. The outcomes of LPI are not significantly different between angle closure subgroups with different iris insertions. However, factors affecting AOD750show differences between two subgroups after LPI.

Association of anterior segment parameters and 5-year incident narrow angles: findings from an older Chinese population

2020 ◽  
pp. bjophthalmol-2020-315852
Author(s):  
Yu Jiang ◽  
Wei Wang ◽  
Lanhua Wang ◽  
Mingguang He
Keyword(s):  
Anterior Chamber ◽  
Multiple Logistic Regression Analysis ◽  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Narrow Angle ◽  
Chamber Volume ◽  
Anterior Chamber Volume ◽  
Oct Imaging ◽  
Older Chinese ◽  
Analysis Models

PurposeTo assess the association of anterior segment optical coherence tomography (AS-OCT) parameters and 5-year incident narrow angle in China.MethodsThis was a prospective cohort study of people aged 50 and older residing in Liwan District, Guangzhou, China. Random clustering sampling was used to identify adults aged 50 years and older in Liwan District, Guangzhou. In 2008 and 2013, this study was repeated and added AS-OCT imaging under dark and light conditions. Customised software (ZAAP) was used to analyse horizontal AS-OCT scans. Angle opening distance (AOD), trabecular iris space area (TISA), anterior chamber volume (ACV) and maximal iris thickness (ITM) were measured. Multiple logistic regression analysis models were used to investigate the associations of the final angle status with baseline AS-OCT parameters. ORs and 95% CIs were calculated.ResultsOf the 220 subjects with eligible AS-OCT images and gonioscopic results in 2008, the response rate was 77.3%. A total of 27 (15.9%) subjects developed narrow angles and 143 (84.1%) had open angles on gonioscopy in 2013. Subjects developed narrow angles had greater spherical equivalent and shallower anterior chamber depth, smaller angle parameters, thicker IT750 and ITM, smaller anterior chamber parameters, greater lens vault, and smaller dynamic parameters (ΔITM, ΔACA, ΔACV) at baseline. After adjusting confounders, the predictors of incident narrow angles included smaller AOD750, TISA750, ΔACA and greater ITM, ΔIarea.ConclusionsIncident narrow angles were associated with smaller anterior ocular dimensions, thicker iris and smaller light-to-dark changes at baseline. These findings can help in early diagnosis in this population.

scholarly journals Biometric Indicators of Anterior Segment Parameters Before and After Laser Peripheral Iridotomy by Swept-Source Optical Coherent Tomography

2021 ◽  
Author(s):  
Bo Yu ◽  
Kang Wang ◽  
Xiaoli Xing
Keyword(s):  
Anterior Chamber ◽  
Anterior Segment ◽  
Angle Closure ◽  
Laser Peripheral Iridotomy ◽  
Swept Source ◽  
Optical Coherent Tomography ◽  
Primary Angle Closure ◽  
Before And After ◽  
Anterior Segment Parameters ◽  
Peripheral Iridotomy

Abstract Background Primary angle closure glaucoma (PACG) is the most common type of glaucoma in China. Laser peripheral iridotomy (LPI) is the primary choice to treat PAC. We aim to evaluate the changes and to find the biometric indicators of anterior segment parameters before and after laser peripheral iridotomy (LPI) in primary angle closure (PAC) eyes using swept-source optical coherent tomography (OCT). Methods LPI was performed in 52 PAC eyes of 28 participants. The change of intraocular pressure and anterior segment parameters, including angle opening distance (AOD500), AOD500 area, trabecular iris space area (TISA500), TISA500 volume, trabecular iris angle (TIA500), iridotrabecular contact (ITC) index, ITC area, anterior chamber volume (ACV), anterior chamber depth (ACD), lens vault (LV) and lens thickness (LT) before and 1 week after LPI were measured by Tomey CASIA2 anterior segment OCT. We also estimate and analyze potential contributing factors possibly affecting the change of anterior chamber angle parameters. Results No post-laser complications were found. The LV and LT did not change significantly 1 week after LPI. AOD500, AOD500 area, TISA500, TISA500 volume, TIA500, ACV and ACD increased significantly after LPI. There was significant decrease in ITC index and ITC area. LT was positively correlated to the change of ITC index (r=0.411, p=0.002) and ITC area (r=0.384, p=0.005). ACD was negatively correlated to the change of ITC index (r=0.292, p=0.036). Conclusions The anterior segment architecture significantly changed after LPI in PAC spectrum eyes. Crystalline lens measurements remained unchanged before and after LPI. AS-OCT can be used to follow anterior chamber parameter changes in PAC spectrum eyes. Pre-treatment LT and ACD affect the therapeutic effect of LPI.

scholarly journals Pupil Size Associated with the Largest Iris Volume in Normal Chinese Eyes

2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Shuning Li ◽  
Jing Jiang ◽  
Yiquan Yang ◽  
Gewei Wu ◽  
Shi-Ming Li ◽  
...  
Keyword(s):  
Anterior Chamber ◽  
Pupil Size ◽  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Quadratic Equation ◽  
Swept Source ◽  
Chamber Volume ◽  
Anterior Chamber Volume ◽  
The Relationship ◽  
Pupillary Size

Background. To determine the range of pupil size that has the largest iris volume in normal eyes. Methods. 31 healthy adult Chinese volunteers underwent swept-source anterior segment OCT examination in both eyes. Pilocarpine 1% was instilled in a randomly selected eye (eye with induced miosis (ME)) of each participant to obtain iris volume (IV) measurements over a range of pupil sizes. OCT was performed prior to and one hour after pilocarpine in both ME and fellow eye (FE). Iris volume (IV), anterior chamber volume (ACV), anterior chamber depth (ACD), and pupil size (PS) were recorded. A scatter plot was used to depict the association between each pupil size and IV. Results. The pupillary sizes for which IV was recorded in ME and FE ranged from 1.161 mm to 6.665 mm. The mean IV increased with miosis in both ME and FE; in 13 eyes, IV decreased with a decrease in pupillary size. PS between 3.812 and 6.665 mm was associated with an increase in IV, while PS between 3.159 and 5.54 mm was associated with a decrease. The relationship between PS and IV was in the shape of a downward parabola and was modeled using a quadratic equation (y = −1.3121x2 + 8.8429x + 16.423, R2 = 0.26886). The largest IV occurred at PS between 3 and 4 mm. Conclusions. The relationship between PS and IV in this study was in the shape of a downward parabola. The largest IV was recorded at a pupillary size between 3 and 4 mm. This trial is registered with ChiCTR-ROC-17013572.

Ocular biometric changes after Ahmed glaucoma valve implantation

2019 ◽  
pp. 112067211988952
Author(s):  
Arezoo Miraftabi ◽  
Mahboubeh Lotfi ◽  
Naveed Nilforushan ◽  
Parya Abdolalizadeh ◽  
Samira Jafari
Keyword(s):  
Anterior Chamber ◽  
Axial Length ◽  
Anterior Chamber Depth ◽  
Ahmed Glaucoma Valve ◽  
Anterior Chamber Angle ◽  
Chamber Volume ◽  
Anterior Chamber Volume ◽  
Valve Implantation ◽  
Ahmed Glaucoma Valve Implantation ◽  
Chamber Angle

Purpose: To investigate the ocular biometric changes after uneventful Ahmed glaucoma valve implantation. Methods: Patients with refractory glaucoma who were candidate for Ahmed valve surgery were prospectively included in this study. Patients with a history of any kinds of corneal surgery were excluded. Refractive status, intraocular pressure, axial length, anterior chamber parameters including anterior and posterior mean keratometry, central corneal thicknesses, and anterior chamber depth, anterior chamber volume, and anterior chamber angle were evaluated at baseline and 1 and 3 months after surgery. Results: A total of 20 eyes from 20 patients were included. Mean intraocular pressure at baseline was 33.4 ± 12.3 mm Hg that significantly decreased to 14.6 ± 6.2 mm Hg at 1 month and 13.5 ± 4.3 mm Hg at 3 months after Ahmed glaucoma valve implantation ( p < 0.001). Mean number of medications was 3.6 ± 1.3 at baseline which significantly decreased to 1.0 ± 1.3 at 3 months after Ahmed glaucoma valve implantation ( p < 0.001). Axial length decreased significantly from 23.69 ± 1.95 to 23.47 ± 1.91 mm ( p < 0.001) at month 3. There were no significant changes in other parameters such as mean spherical equivalent, anterior chamber volume, anterior chamber angle, anterior chamber depth, and keratometry at the end of month 3 after surgery ( p > 0.05 in all). Conclusion: Ahmed glaucoma valve implantation had a significant effect on axial length at 3 months after surgery but its effect on keratometry and other anterior chamber parameters was not significant.

scholarly journals Measurement of and Factors Associated with the Anterior Chamber Volume in Healthy Chinese Adults

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Yuan Zong ◽  
Qian Xu ◽  
Chunhui Jiang ◽  
Haohao Zhu ◽  
Jian Yu ◽  
...  
Keyword(s):  
Anterior Chamber ◽  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Chinese Adults ◽  
Factors Associated ◽  
Chamber Volume ◽  
Significant Difference ◽  
Anterior Chamber Volume ◽  
Anterior Segment Parameters ◽  
Healthy Chinese

Purpose. To measure the anterior chamber volume (ACV) and determine factors associated with the ACV in healthy Chinese adults.Methods. In this cross-sectional study, we used swept-source optical coherence tomography (SS-OCT) to measure ACV and other anterior segment parameters. Factors associated with ACV were also determined.Results. A total of 313 healthy Chinese adults were enrolled. The anterior segment parameters, including ACV, could be measured by SS-OCT with excellent repeatability and reproducibility. There was a significant difference between the horizontal and vertical anterior chamber widths (ACW) (P<0.05), with a mean difference of 390 μm. The ACV (mean153.83±32.42 mm3) was correlated with most of the anterior segment parameters, especially anterior chamber depth (ACD), which accounted for about 85% of the variation of ACV. Most of the anterior segment parameters were significantly correlated with age, and the relative changes in ACV and ACD were greatest in subjects aged 41–50 years.Conclusion. ACV was correlated with most of the anterior segment parameters measured in this study, particularly ACD. The relatively large difference between horizontal and vertical ACW suggests that the ACV could and should be measured using multiple OCT scans.

scholarly journals Prediction of anterior chamber volume after implantation of posterior chamber phakic intraocular lens

PLoS ONE ◽  
2020 ◽  
Vol 15 (11) ◽  
pp. e0242434
Author(s):  
Yuki Takagi ◽  
Takashi Kojima ◽  
Tomoya Nishida ◽  
Tomoaki Nakamura ◽  
Kazuo Ichikawa
Keyword(s):  
Anterior Chamber ◽  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Absolute Error ◽  
Prediction Equation ◽  
Stepwise Multiple Regression ◽  
Posterior Chamber ◽  
Implantable Collamer Lens ◽  
Chamber Volume ◽  
Anterior Chamber Volume

Purpose To predict the anterior chamber volume (ACV) after implantable collamer lens (ICL) implantation based on ICL size and parameters of anterior segment optical coherence tomography (AS-OCT). Design Retrospective study. Methods This study included 222 eyes of 222 patients who underwent ICL implantation at Nagoya Eye Clinic. The patients were divided into two groups: prediction group, for creating the prediction equation (148 eyes, mean age: 32.11 ± 8.04 years), and verification group, for verifying the equation (74 eyes, mean age: 33.03 ± 6.74 years). The angle opening distance (AOD), anterior chamber width (ACW), ACV, anterior chamber depth, lens vault, angle-to-angle distance, angle recess area, and trabecular iris space area were calculated using AS-OCT. A stepwise multiple regression analysis was performed. After the creation of the prediction equation, its accuracy was verified in the verification group. Results The ACV, AOD750, ACW, and ICL size were selected as explanatory variables to predict postoperative ACV. Mean predicted (114.2 ± 21.83 mm3) and actual postoperative ACVs (116.1 ± 25.41 mm3) were not significantly different (P = 0.269); absolute error was 10.59 ± 9.13 mm3. In addition, there was high correlation between actual and predictive ACV (adjusted R2 = 0.6996, p < 0.0001). Bland-Altman plot revealed that there was no addition or proportional error between predicted and actual postoperative ACV. Conclusion Postoperative ACV was accurately predicted using AS-OCT parameters and ICL size. This prediction equation may be useful for making decisions regarding ICL size.

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