Polymer Gels in Vaginal Drug Delivery Systems

2018 ◽  
pp. 197-246
Author(s):  
María-Dolores Veiga ◽  
Roberto Ruiz-Caro ◽  
Araceli Martín-Illana ◽  
Fernando Notario-Pérez ◽  
Raúl Cazorla-Luna
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Polymer Gels ◽  
Delivery Systems ◽  
Vaginal Drug Delivery

Development of starch based mucoadhesive vaginal drug delivery systems for application in veterinary medicine

2016 ◽  
Vol 136 ◽  
pp. 63-70 ◽  
Author(s):  
Mehmet Koray Gök ◽  
Saadet Özgümüş ◽  
Kamber Demir ◽  
Ümüt Cirit ◽  
Serhat Pabuccuoğlu ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Veterinary Medicine ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Vaginal Drug Delivery

scholarly journals Vaginal Drug Delivery Systems for HIV Prevention

2009 ◽  
Vol 11 (1) ◽  
Author(s):  
Lisa Cencia Rohan ◽  
Alexandra B. Sassi
Keyword(s):  
Drug Delivery ◽  
Hiv Prevention ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Vaginal Drug Delivery

Novel Vaginal Drug Delivery Systems: A Review

2010 ◽  
Vol 5 (2) ◽  
pp. 95-104 ◽  
Author(s):  
Umme Hani ◽  
R. Sudeendra Bhat ◽  
Ritesh Sisodiya ◽  
Hosakote Gurumallappa Shivakumar
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Vaginal Drug Delivery

Gels as vaginal drug delivery systems

2006 ◽  
Vol 318 (1-2) ◽  
pp. 1-14 ◽  
Author(s):  
J. das Neves ◽  
M.F. Bahia
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Vaginal Drug Delivery

scholarly journals Vaginal Mucoadhesive Drug Delivery System

2021 ◽  
pp. 123-133
Author(s):  
Bhaskar Mohite ◽  
Rakesh Patel ◽  
Nandu Kayande ◽  
Raju Thenge
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
The Body ◽  
Factors Affecting ◽  
Vaginal Drug Delivery ◽  
Mucosal Surfaces ◽  
Delivery Routes

Mucoadhesive drug delivery systems are delivery systems which utilize the property of bioadhesion of certain polymers which become adhesive on hydration and hence can be used for targeting a drug to a particular region of the body for extended periods of time. Many of these delivery routes, particularly those through the nasal, ocular, reproductive and gastrointestinal system, involve contact with mucosal surfaces. The gastrointestinal route has been particularly popular among medical staff and patients alike. Although convenient, unfortunately, this route can be very inefficient for a number of reasons, including too rapid transit of the drug-containing delivery system past the optimum site for absorption, which is normally the small intestine and to a lesser degree the stomach and colon. Mucoadhesive formulations use polymers as the adhesive component. Mucoadhesive drug delivery systems are available in the form of tablets, films, patches, and gels for oral, buccal, nasal, ocular, vaginal, rectal and topical routes for both systemic and local effects. This review article represents the various aspects of vaginal drug delivery system, bioadhesion mechanism, Theory of bioadhesion, factors affecting bioadhesion, various types of vaginal formulation etc.

Development of Thiolated Chitosan Nanoparticles Based Mucoadhesive Vaginal Drug Delivery Systems

2017 ◽  
Vol 59 (6) ◽  
pp. 858-865 ◽  
Author(s):  
M. Hasanifard ◽  
B. Ebrahimi-Hosseinzadeh ◽  
A. Hatamian-Zarmi ◽  
A. H. Rezayan ◽  
M. A. Esmaeili
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Chitosan Nanoparticles ◽  
Delivery Systems ◽  
Thiolated Chitosan ◽  
Vaginal Drug Delivery

Techniques For The Preparation of Tissue Samples Containing Injectable Polymer Microcapsules

1985 ◽  
Vol 43 ◽  
pp. 710-711
Author(s):  
G.E. Visscher ◽  
R. L. Robison ◽  
G. J. Argentieri
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Gastrocnemius Muscle ◽  
Degradation Process ◽  
Delivery Systems ◽  
Tissue Reaction ◽  
Electron Microscopic ◽  
Tissue Samples ◽  
Injectable Polymer ◽  
Microscopic Techniques

The use of various bioerodable polymers as drug delivery systems has gained considerable interest in recent years. Among some of the shapes used as delivery systems are films, rods and microcapsules. The work presented here will deal with the techniques we have utilized for the analysis of the tissue reaction to and actual biodegradation of injectable microcapsules. This work has utilized light microscopic (LM), transmission (TEM) and scanning (SEM) electron microscopic techniques. The design of our studies has utilized methodology that would; 1. best characterize the actual degradation process without artifacts introduced by fixation procedures and 2. allow for reproducible results.In our studies, the gastrocnemius muscle of the rat was chosen as the injection site. Prior to the injection of microcapsules the skin above the sites was shaved and tattooed for later recognition and recovery. 1.0 cc syringes were loaded with the desired quantity of microcapsules and the vehicle (0.5% hydroxypropylmethycellulose) drawn up. The syringes were agitated to suspend the microcapsules in the injection vehicle.

Sign in / Sign up

Export Citation Format

Share Document