Negative Effects of Mechanical Bowel Preparation on the Postoperative Intestinal Motility of Patients with Colorectal Cancer

Introduction Colorectal cancer is the most common gastrointestinal cancer treated by departments and surgical clinics in Poland. Currently, the biggest challenge of surgery is to reduce the number of leaks in the bowel anastomoses and postoperative wound infections to a minimum. Objective Whether bowel preparation before surgery affects the early results of treatment? Methods The study was retrospective and included patients operated electively on one surgical center due to colorectal and rectal cancer in years 2013-2018. Patients who underwent surgery were divided into two groups in the study. The first was 109 patients with mechanical bowel irrigation. The second group of 118 patients, in addition to mechanical bowel preparation, received an oral antibiotic. Results The studied groups did not differ significantly in terms of traits that could affect the results of treatment within 30 days of surgery. Postoperative mortality was 0,9% and 0,85%. Complications: leakage of the bowel anastomosis 1,8% and 1,7%, postoperative obstruction 3,7% and 5,0%, wound dehiscence 2,75% and 0,85%, infection of the surgical site 13,8% and 3,4% respectively in the first and second group of patients. Conclusion 1. Mechanical bowel preparation in combination with the oral supply of antibiotic significantly reduces the frequency of surgical site infection compared to the mechanical rinsing itself. 2. Type of preparation of the intestine before the surgery does not significantly affect postoperative mortality and other complications, including anastomotic leak, but may be important for the frequency of postoperative wound dehiscence.

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Hospital based randomized prospective study outcomes in colorectal surgery after bowel preparation

International Surgery Journal ◽

10.18203/2349-2902.isj20201395 ◽

2020 ◽

Vol 7 (4) ◽

pp. 1191

Author(s):

Altaf Hussain Bhat ◽

Gh Hussain Mir ◽

Sajad Ahmad Bhat ◽

Muzaffar Ali

Keyword(s):

Colorectal Cancer ◽

Colorectal Surgery ◽

Prospective Study ◽

Bowel Preparation ◽

Genetic Disorders ◽

Mechanical Bowel Preparation ◽

Minimal Invasive ◽

Elective Colorectal Surgery ◽

Group 2 ◽

Group 1

Background: Research of so many years from the procurable world data has shown that the reasons for most colorectal cancers occur due to change in life style the type of diet, smoking as well as the influence of the surrounding environment in which man lives and increasing age with only a minority of cases associated with genetic disorders. Colorectal cancer is the third most commonly diagnosed cancer. In the first half of the 20th century, mortality from colorectal surgery often exceeded 20%, mainly attributed to sepsis.Methods: The randomized prospective study was conducted on 202 colorectal cancer patients in the department of Colorectal division of General and Minimal Invasive surgery” Sher-i-Kashmir Institute of Medical Sciences, Srinagar.Results: Mean age of patients in Group 1 (with no mechanical bowel preparation (NMBP)) was 51±18.15 years while as same was 50±17.76 years for Group 2 (with mechanical bowel preparation (MBP)). Age range for Group 1 was 16-87 years and16-85 years for Group 2. Regarding outcomes, wound infections were 6.1% and 3.8% in Group 1 and Group 2 respectively. While disruption of anastomosis were 2.0% and 3.8% in group A and B respectively.Conclusions: Statistically no gross difference in terms of morbidity and mortality was found between the use of mechanical bowel preparation versus no use of mechanical bowel preparation in elective colorectal surgery. Elective Colorectal Surgery can safely be performed without enduring MBP in it as it does not possess any sorts of benefits.

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The impact of preoperative preparation on postoperative complications in patients with colorectal cancer

Romanian Journal of Medical Practice ◽

10.37897/rjmp.2016.4.4 ◽

2016 ◽

Vol 11 (4) ◽

pp. 311-316

Author(s):

Octavia Cristina RUSU ◽

◽

Radu Virgil COSTEA ◽

Cristian Constantin POPA ◽

Ştefan Ilie NEAGU ◽

...

Keyword(s):

Colorectal Cancer ◽

Postoperative Complications ◽

Bowel Preparation ◽

Nutritional Support ◽

Mechanical Bowel Preparation ◽

Antimicrobial Treatment ◽

Cancer Death ◽

Preoperative Preparation ◽

Meta Analyses ◽

The Impact

Colorectal cancer is a frequently encountered disease. In most countries, it represents the second leading cause of cancer death. The treatment with radical intent of this condition is surgical. Objective: Through this study, we want to update some data regarding the impact of nutrition and the preoperative mechanical bowel preparation on postoperative complications, in patients who need surgical treatment for colorectal cancer. Material and Method: Relevant articles in the field, contained in international databases were analysed, with no language exclusion, including clinical trials and meta-analyses performed between 1994 and 2015. Conclusions: Preoperative preparation is particularly important in the postoperative evolution of the patients with colorectal cancer and it is based on several main principles: nutritional support, antimicrobial treatment and mechanical bowel preparation.

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Preoperative mechanical large bowel preparation in colorectal cancer surgery

Health and Ecology Issues ◽

10.51523/2708-6011.2021-18-2-4 ◽

2021 ◽

pp. 25-32

Author(s):

A. P. Dyatlov ◽

I. V. Mikhailov ◽

V. A. Kudryashov ◽

K. A. Gned`ko

Keyword(s):

Colorectal Cancer ◽

Colon Cancer ◽

Comparative Analysis ◽

Bowel Preparation ◽

Mechanical Bowel Preparation ◽

Incidence Rates ◽

Colorectal Cancer Surgery ◽

Death Rates ◽

Surgical Interventions ◽

Postoperative Death

Objective: to analyze literature data on the effectiveness of preoperative mechanical bowel preparation (MBP), and on the basis of our own data to perform a comparative analysis of immediate MBP results in patients operated on right-sided colon cancer.Materials and methods. We reviewed literature data relevant to the use of MBP and performed a retrospective analysis of the immediate results of surgical interventions on right-sided colon cancer in 349 patients having undergone MBP with polyethylene glycol (PEG) compounds (n = 186) and without the use of PEG (n = 163).Results. The incidence rates of complications in the patients of groups I and II were 6.7 % and 9.8 % (P>0.05), anastomotic leak rates were 0.6 % and 1.6 % (P>0.05), postoperative death rates — 1.2 % and 1.6 % (P>0.05), the average durations of the postoperative period were 14.9 and 12.1 days, respectively (P>0.05).Conclusion. The use of preoperative MBP with PEG compounds does not result in enhancing the immediate results of the surgical treatment of patients with right-sided cancer.

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Comparative Study of Postoperative Complications in Patients With and Without an Obstruction Who Had Left-Sided Colorectal Cancer and Underwent a Single-Stage Operation After Mechanical Bowel Preparation

Annals of Coloproctology ◽

10.3393/ac.2014.30.6.251 ◽

2014 ◽

Vol 30 (6) ◽

pp. 251 ◽

Cited By ~ 3

Author(s):

Sang Hun Jung ◽

Jae Hwang Kim

Keyword(s):

Colorectal Cancer ◽

Postoperative Complications ◽

Comparative Study ◽

Bowel Preparation ◽

Mechanical Bowel Preparation ◽

Single Stage

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Intestinal motility distal of a deviating ileostomy after rectal resection with the construction of a primary anastomosis: results of the prospective COLO-MOVE study

International Journal of Colorectal Disease ◽

10.1007/s00384-020-03651-6 ◽

2020 ◽

Vol 35 (10) ◽

pp. 1959-1962

Author(s):

T. A. Burghgraef ◽

F. J. Amelung ◽

P. M. Verheijen ◽

I. A. M. J. Broeders ◽

E. C. J. Consten

Keyword(s):

Bowel Preparation ◽

Intestinal Motility ◽

Rectal Resection ◽

Primary Anastomosis ◽

Mechanical Bowel Preparation ◽

X Rays ◽

Diverting Ileostomy ◽

Right Colon ◽

Distal Marker ◽

Preoperative Bowel Preparation

Abstract Purpose No consensus exists regarding the use of preoperative bowel preparation for patients undergoing a low anterior resection (LAR). Several comparative studies show similar outcomes when a single time enema (STE) is compared with mechanical bowel preparation (MBP). It is hypothesized that STE is comparable with MBP due to a decrease in intestinal motility distal of a newly constructed diverting ileostomy (DI). Methods In this prospective single-centre cohort study, patients undergoing a LAR with primary anastomosis and DI construction were given a STE 2 h pre-operatively. Radio-opaque markers were inserted in the efferent loop of the DI during surgery, and plain abdominal X-rays were made during the first, third, fifth and seventh postoperative day to visualize intestinal motility. Results Thirty-nine patients were included. Radio-opaque markers were situated in the ileum or right colon in 100%, 100% and 97.1% of the patients during respectively the first, third and fifth postoperative day. One patient had its most distal marker situated in the left colon during day five. In none of the patients, the markers were seen distal of the anastomosis. Conclusion Intestinal motility distally of the DI is decreased in patients who undergo a LAR resection with the construction of an anastomosis and DI, while preoperatively receiving a STE.

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