Focused on the operation management of equipment, the workflow of NC equipment informatization management was deeply analyzed in this article. The functional structure of equipment management system was studied here. And, the equipment information management system was developed based on B/S structure. The system was applied to manage the basic information, Spare parts and Maintenance of the NC Equipment by way of information and automation, and realize the traceability of equipment maintenance and spare parts management throughout the whole Life Cycle. The alete integration of the Equipment Information Management System and other system, such as DNC, MES and ERP, was realized. And the integrated system effectively promoted the information interaction between layer of enterprise, workshop and equipment.