With the power increase of the wind turbine, the scale of the blade is increasing, further improving the performance of the blade, improving the stiffness and stability of the blade, inhibiting the vibration and noise of the blade and reducing the blade weight has become an problem urgently needed to be solved with for the design of the large wind turbine blade. The unique external shape of organisms, the perfect unity of the function, structure and material, the excellent capability for adapting the environment, also provides an inexhaustible inspiration for the bionic design of wind turbine. Applying the biological non-smooth and self-cleaning effect and imitating the biological medial axis pattern structure, self-adaptive characteristics conduct the bionic design of the wind turbine blade, it can effectively realize drag-reduction and lift enhancement for the blades, noise reduction, lightweight, and can improve the self-adaptive ability, resisting wind and sand, preventing icing up. Paying attention to research on biological mechanism, perfecting the bionic design theory, implementing the multidisciplinary design optimization, strengthening the research on model, have an important significance on improving the bionic design effect for the wind turbine blade and promoting the bionic engineering application.