The Application of Mass Spectrometry in Drug Metabolism and Pharmacokinetics

Advances in Experimental Medicine and Biology - Advanced Imaging and Bio Techniques for Convergence Science ◽

10.1007/978-981-33-6064-8_20 ◽

2021 ◽

pp. 533-550

Author(s):

Ji-Yoon Lee ◽

Sang Kyum Kim ◽

Kiho Lee ◽

Soo Jin Oh

Keyword(s):

Mass Spectrometry ◽

Drug Metabolism

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Rapid and sensitive drug metabolism studies by SU-8 microchip capillary electrophoresis-electrospray ionization mass spectrometry

Journal of Chromatography A ◽

10.1016/j.chroma.2010.12.010 ◽

2011 ◽

Vol 1218 (5) ◽

pp. 739-745 ◽

Author(s):

Nina Nordman ◽

Tiina Sikanen ◽

Maria-Elisa Moilanen ◽

Susanna Aura ◽

Tapio Kotiaho ◽

...

Keyword(s):

Mass Spectrometry ◽

Capillary Electrophoresis ◽

Drug Metabolism ◽

Electrospray Ionization ◽

Electrospray Ionization Mass Spectrometry ◽

Ionization Mass Spectrometry ◽

Ionization Mass ◽

Microchip Capillary Electrophoresis

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An introduction to hybrid ion trap/time-of-flight mass spectrometry coupled with liquid chromatography applied to drug metabolism studies

Journal of Mass Spectrometry ◽

10.1002/jms.3126 ◽

2012 ◽

Vol 47 (12) ◽

pp. 1627-1642 ◽

Author(s):

Zhao-Ying Liu

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Drug Metabolism ◽

Ion Trap ◽

Time Of Flight ◽

Flight Mass Spectrometry

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The Impact of Drug Metabolism in Contemporary Drug Discovery: New Opportunities and Challenges for Mass Spectrometry

Mass Spectrometry in Biology & Medicine ◽

10.1007/978-1-59259-719-2_24 ◽

2000 ◽

pp. 481-496 ◽

Author(s):

Thomas A. Baillie ◽

Paul G. Pearson

Keyword(s):

Mass Spectrometry ◽

Drug Discovery ◽

Drug Metabolism ◽

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Electrostatic Spray Ionization from 384-Well Microtiter Plates for Mass Spectrometry Analysis-Based Enzyme Assay and Drug Metabolism Screening

Analytical Chemistry ◽

10.1021/acs.analchem.7b00536 ◽

2017 ◽

Vol 89 (11) ◽

pp. 5983-5990 ◽

Author(s):

Liang Qiao ◽

Xiaoqin Zhong ◽

Emna Belghith ◽

Yan Deng ◽

Tzu-En Lin ◽

...

Keyword(s):

Mass Spectrometry ◽

Drug Metabolism ◽

Enzyme Assay ◽

Mass Spectrometry Analysis ◽

Spectrometry Analysis ◽

Microtiter Plates ◽

Electrostatic Spray

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Advances in the application of mass spectrometry to studies of drug metabolism, pharmacokinetics and toxicology

Advances in Mass Spectrometry ◽

10.1016/b978-0-444-88871-6.50020-9 ◽

1992 ◽

pp. 289-314

Author(s):

Thomas A. Baillie

Keyword(s):

Mass Spectrometry ◽

Drug Metabolism

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Microdosing Assessment to Evaluate Pharmacokinetics and Drug Metabolism in Rats Using Liquid Chromatography-Tandem Mass Spectrometry

Pharmaceutical Research ◽

10.1007/s11095-008-9555-x ◽

2008 ◽

Vol 25 (7) ◽

pp. 1572-1582 ◽

Author(s):

Jinsong Ni ◽

Hui Ouyang ◽

Mauro Aiello ◽

Carmai Seto ◽

Lisa Borbridge ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Drug Metabolism ◽

Tandem Mass Spectrometry ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass ◽

Pharmacokinetics And Drug Metabolism

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Studies on drug metabolism using liquid chromatography/mass spectrometry: Comparison of three liquid chromatographic/mass spectrometric interfaces

Biological Mass Spectrometry ◽

10.1002/bms.1200230903 ◽

1994 ◽

Vol 23 (9) ◽

pp. 540-546 ◽

Author(s):

Haruo Iwabuchi ◽

Eiichi Kitazawa ◽

Nobuhiro Kobayashi ◽

Hidetoshi Watanabe ◽

Michiko Kanai ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Drug Metabolism ◽

Mass Spectrometric ◽

Liquid Chromatography Mass Spectrometry ◽

Chromatography Mass Spectrometry ◽

Liquid Chromatographic ◽

Chromatographic Mass

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On-Chip Electromembrane Extraction for Monitoring Drug Metabolism in Real Time by Electrospray Ionization Mass Spectrometry

Methods in Molecular Biology - Microchip Capillary Electrophoresis Protocols ◽

10.1007/978-1-4939-2353-3_15 ◽

2015 ◽

pp. 171-182 ◽

Author(s):

Nickolaj J. Petersen ◽

Henrik Jensen ◽

Stig Pedersen-Bjergaard

Keyword(s):

Mass Spectrometry ◽

Drug Metabolism ◽

Electrospray Ionization ◽

Real Time ◽

Electrospray Ionization Mass Spectrometry ◽

Ionization Mass Spectrometry ◽

Ionization Mass ◽

Monitoring Drug ◽

Electromembrane Extraction ◽

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O-203b Paediatric Microdose Study Of [14c]paracetamol To Study Drug Metabolism Using Accelerated Mass Spectrometry: Proof Of Concept

Archives of Disease in Childhood ◽

10.1136/archdischild-2014-307384.273 ◽

2014 ◽

Vol 99 (Suppl 2) ◽

pp. A102.1-A102

Author(s):

MG Mooij ◽

E van Duijn ◽

CA Knibbe ◽

W Vaes ◽

B Fabriek ◽

...

Keyword(s):

Mass Spectrometry ◽

Drug Metabolism ◽

Proof Of Concept ◽

Microdose Study

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Using mass spectrometry for drug metabolism studies

Journal of the American Society for Mass Spectrometry ◽

10.1016/j.jasms.2006.04.016 ◽

2006 ◽

Vol 17 (8) ◽

pp. 1188-1192

Author(s):

R. Ramanathan

Keyword(s):

Mass Spectrometry ◽

Drug Metabolism

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