scholarly journals Renal changes in long-term Type 1 (insulin-dependent) diabetic patients with and without clinical nephropathy: a light microscopic, morphometric study of autopsy material

Diabetologia ◽  
1984 ◽  
Vol 26 (5) ◽  
Author(s):  
O.Fr�kj�r Thomsen ◽  
A.R. Andersen ◽  
J.Sandahl Christiansen ◽  
T. Deckert
Keyword(s):  
Morphometric Study ◽  
Diabetic Patients ◽  
Autopsy Material ◽  
Renal Changes ◽  
Insulin Dependent ◽  
Insulin Dependent Diabetic ◽  
Term Type

Regional cerebral hypoperfusion in long-term Type 1 (insulin-dependent) diabetic patients

1995 ◽  
Vol 16 (1) ◽  
pp. 10-16 ◽  
Author(s):  
B. KEYMEULEN ◽  
A. JACOBS ◽  
K. DE METZ ◽  
C. DE SADELEER ◽  
A. BOSSUYT ◽  
...  
Keyword(s):  
Cerebral Hypoperfusion ◽  
Diabetic Patients ◽  
Insulin Dependent ◽  
Insulin Dependent Diabetic ◽  
Term Type

Decreased distensibility of resistance vessels of the skin in type 1 (insulin-dependent) diabetic patients with microangiopathy

1987 ◽  
Vol 72 (1) ◽  
pp. 123-130 ◽  
Author(s):  
J. Kastrup ◽  
T. Nørgaard ◽  
H.-H. Parving ◽  
N. A. Lassen
Keyword(s):  
Blood Flow ◽  
Inverse Correlation ◽  
Diabetic Patients ◽  
Resistance Vessels ◽  
Head Up Tilt ◽  
Insulin Dependent ◽  
Insulin Dependent Diabetic ◽  
Type 1 Diabetic Patients ◽  
Term Type

1. The distensibility of the resistance vessels of the skin at the dorsum of the foot was determined in 11 long-term type 1 (insulin-dependent) diabetic patients with nephropathy and retinopathy, nine short-term type 1 diabetic patients without clinical microangiopathy and in nine healthy non-diabetic subjects. 2. Blood flow was measured by the local 133Xexenon washout technique in a vascular bed locally paralysed by the injection of histamine. Blood flow was measured before, during and after a 40 mmHg increase of the vascular transmural pressure, induced by head-up tilt. 3. The mean increase in blood flow during headup tilt was only 24% in diabetic subjects with and 48% in diabetic patients without clinical microangiopathy, compared with 79% in normal non-diabetic subjects (P < 0.0005 and P < 0.05, respectively). 4. An inverse correlation between microvascular distensibility and degree of hyalinosis of the terminal arterioles in biopsies from the skin was demonstrated (r = − 0.57, P < 0.001). 5. Our results suggest that terminal arteriolar hyalinosis reduces the microvascular distensibility and probably increases the minimal vascular resistance, thereby impeding hyperaemic responses.

scholarly journals Long-term effects of linoleic-acid-enriched diet on albuminuria and lipid levels in Type 1 (insulin-dependent) diabetic patients with elevated urinary albumin excretion

Diabetologia ◽  
1992 ◽  
Vol 35 (2) ◽  
pp. 165-172 ◽  
Author(s):  
R. P. F. Dullaart ◽  
B. J. Beusekamp ◽  
S. Meijer ◽  
K. Hoogenberg ◽  
J. J. van Doormaal ◽  
...  
Keyword(s):  
Linoleic Acid ◽  
Urinary Albumin Excretion ◽  
Urinary Albumin ◽  
Diabetic Patients ◽  
Lipid Levels ◽  
Long Term Effects ◽  
Insulin Dependent ◽  
Insulin Dependent Diabetic
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