scholarly journals Increased myocardial contractility in short-term Type 1 diabetic patients: an echocardiographic study

Diabetologia ◽  
1985 ◽  
Vol 28 (11) ◽  
pp. 822-826 ◽  
Author(s):  
L. Thuesen ◽  
J. Sandahl Christiansen ◽  
N. Falstie-Jensen ◽  
C. K. Christensen ◽  
K. Hermansen ◽  
...  
2017 ◽  
Author(s):  
Federica Ermetici ◽  
Silvia Briganti ◽  
Stefano Benedini ◽  
Roberto Codella ◽  
Paola Maffi ◽  
...  

1987 ◽  
Vol 72 (1) ◽  
pp. 123-130 ◽  
Author(s):  
J. Kastrup ◽  
T. Nørgaard ◽  
H.-H. Parving ◽  
N. A. Lassen

1. The distensibility of the resistance vessels of the skin at the dorsum of the foot was determined in 11 long-term type 1 (insulin-dependent) diabetic patients with nephropathy and retinopathy, nine short-term type 1 diabetic patients without clinical microangiopathy and in nine healthy non-diabetic subjects. 2. Blood flow was measured by the local 133Xexenon washout technique in a vascular bed locally paralysed by the injection of histamine. Blood flow was measured before, during and after a 40 mmHg increase of the vascular transmural pressure, induced by head-up tilt. 3. The mean increase in blood flow during headup tilt was only 24% in diabetic subjects with and 48% in diabetic patients without clinical microangiopathy, compared with 79% in normal non-diabetic subjects (P < 0.0005 and P < 0.05, respectively). 4. An inverse correlation between microvascular distensibility and degree of hyalinosis of the terminal arterioles in biopsies from the skin was demonstrated (r = − 0.57, P < 0.001). 5. Our results suggest that terminal arteriolar hyalinosis reduces the microvascular distensibility and probably increases the minimal vascular resistance, thereby impeding hyperaemic responses.


2012 ◽  
Vol 38 (1) ◽  
pp. 174-179 ◽  
Author(s):  
Jonas Vejvad Nørskov Laursen ◽  
Stine Skovbo Hoffmann ◽  
Anders Green ◽  
Mads Nybo ◽  
Anne Katrin Sjølie ◽  
...  

2003 ◽  
Vol 20 (5) ◽  
pp. 375-381 ◽  
Author(s):  
N. Hattori ◽  
J. Rihl ◽  
F. M. Bengel ◽  
S. G. Nekolla ◽  
E. Standl ◽  
...  

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