Changes in sex hormone binding globulin, high density lipoprotein cholesterol and plasma lipids in male cyclists during training and competition

Author(s):  
M. J. Caballero ◽  
P. Mena ◽  
M. Maynar
1991 ◽  
Vol 1 (3) ◽  
pp. 265-278 ◽  
Author(s):  
John Warber ◽  
Terry Bazzarre

The effect of weight lifting and running on the plasma lipid profiles of a physically fit 32-year-old hypercholesterolemic male were determined while he adhered to a controlled Phase III American Heart Association diet. The subject followed the same daily menu pattern for the entire test period. He completed four treatment phases: 6 weeks of detraining, 10 weeks of weight lifting, 10 weeks of running, and 10 weeks of weight lifting. The study was designed to closely compare two modes of exercise training for the same duration. A complete lipid profile was analyzed at baseline and every 5 weeks thereafter. Body weight and body fat remained constant throughout the study. Results revealed that running was the only effective treatment in raising high-density lipoprotein cholesterol (HDL-C). A return to weight lifting was associated with a 4 mg % decrease in HDLC. The controlled low-fat, high carbohydrate, and low cholesterol diet effectively reduced total cholesterol, low-density, and high-density lipoprotein cholesterol in this hypercholesterolemic subject, while running increased HDL-C.


1984 ◽  
Vol 53 (9) ◽  
pp. 1259-1263 ◽  
Author(s):  
Wanju S. Dai ◽  
James P. Gutai ◽  
Lewis H. Kuller ◽  
Ronald E. Laporte ◽  
Lorita Falvo-Gerard ◽  
...  

1993 ◽  
Vol 129 (2) ◽  
pp. 130-133 ◽  
Author(s):  
Charles PT Schijf ◽  
Marius J van der Mooren ◽  
Wim H Doesburg ◽  
Chris MG Thomas ◽  
Rune Rolland

Fifty-four healthy women were studied during the follicular and the luteal phase of one menstrual cycle to determine possible cyclic influences on several parameters. After a 12-h overnight fast, blood samples were obtained between 08.00 h and 09.30 h and processed for total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, apolipoproteins A-I and B and total triglycerides. In the same samples we also measured serum concentrations of follicle-stimulating hormone, luteinizing hormone, 17β-oestradiol, progesterone, sex hormone binding globulin and testosterone. Serum total cholesterol, low-density lipoprotein cholesterol and the related apolipoprotein B were decreased significantly with 0.35 mmol/l, 0.44 mmol/l and 15 mg/l, respectively, during the luteal phase as compared to the follicular phase (p≤0.01). The ratios of low-density lipoprotein cholesterol/high-density lipoprotein cholesterol and of total cholesterol/high-density lipoprotein cholesterol were also significantly lower (p <0.01) in the luteal phase because high-density lipoprotein cholesterol and its major carrier apolipoprotein A-I as well as serum triglycerides remained unchanged in the two cycle phases compared. Sex hormone binding globulin was significantly higher (p <0.001) in the luteal phase than in the follicular phase of the investigated cycles, whereas serum testosterone remained unchanged in the two cycle phases compared. Therefore, the free androgen index decreased in the luteal phase (p<0.01). These results indicate the necessity to define the cycle phase in which blood has been collected during control cycles in studies concentrating on possible effects of oral contraceptives or other administered sex steroids on serum lipids, lipoproteins and androgen metabolism. Further, we suggest that variations in the serum concentrations of lipids and lipoproteins during the normal menstrual cycle should be considered when normal range values are defined.


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