A Comparison between Running and Weight Lifting on Fasting Plasma Lipids of a Well-Conditioned Hypercholesterolemic Male

1991 ◽  
Vol 1 (3) ◽  
pp. 265-278 ◽  
Author(s):  
John Warber ◽  
Terry Bazzarre
Keyword(s):  
High Density Lipoprotein ◽  
High Density Lipoprotein Cholesterol ◽  
Plasma Lipids ◽  
Plasma Lipid ◽  
Density Lipoprotein ◽  
Weight Lifting ◽  
High Density ◽  
Lipoprotein Cholesterol ◽  
Phase Iii ◽  
Study Results

The effect of weight lifting and running on the plasma lipid profiles of a physically fit 32-year-old hypercholesterolemic male were determined while he adhered to a controlled Phase III American Heart Association diet. The subject followed the same daily menu pattern for the entire test period. He completed four treatment phases: 6 weeks of detraining, 10 weeks of weight lifting, 10 weeks of running, and 10 weeks of weight lifting. The study was designed to closely compare two modes of exercise training for the same duration. A complete lipid profile was analyzed at baseline and every 5 weeks thereafter. Body weight and body fat remained constant throughout the study. Results revealed that running was the only effective treatment in raising high-density lipoprotein cholesterol (HDL-C). A return to weight lifting was associated with a 4 mg % decrease in HDLC. The controlled low-fat, high carbohydrate, and low cholesterol diet effectively reduced total cholesterol, low-density, and high-density lipoprotein cholesterol in this hypercholesterolemic subject, while running increased HDL-C.

scholarly journals The effect of triglycerides to high-density lipoprotein cholesterol ratio on the reduction of renal function: findings from China health and retirement longitudinal study (CHARLS)

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Shiqi Lv ◽  
Han Zhang ◽  
Jing Chen ◽  
Ziyan Shen ◽  
Cheng Zhu ◽  
...  
Keyword(s):  
Renal Function ◽  
Longitudinal Study ◽  
High Density Lipoprotein ◽  
High Density Lipoprotein Cholesterol ◽  
Chinese Population ◽  
Density Lipoprotein ◽  
High Density ◽  
Lipoprotein Cholesterol ◽  
Smoking History ◽  
Study Results

Abstract Background Previous studies show that abnormal lipoprotein metabolism can increase the prevalence of chronic kidney disease (CKD). This study prospectively investigated the association of triglycerides to high-density lipoprotein cholesterol (TG/HDL-C) ratio and renal dysfunction in the Chinese population. Methods This longitudinal cohort research examined 7,316 participants (age range: 22–93) from the China Health and Retirement Longitudinal Study (CHARLS), including 6,560 individuals with estimated glomerular filtration rate (eGFR) ≥ 60 mL/min/1.73 m2 (normal renal function, NRF) group and 756 with eGFR < 60 mL/min/1.73 m2 (impaired renal function, IRF) group. In NRF group, reduction in renal function was defined as eGFR < 60 mL/min/1.73 m2 at exit visit and in IRF group, it was defined as decline in eGFR category, average eGFR decline > 5 mL/min/1.73 m2 per year or > 30 % decrease in eGFR from baseline. Results The study results showed that TG/HDL-C ratio was positively associated with the risk of renal function decline in the NRF group (OR 1.30, 95 %CI 1.03–1.65, P = 0.03) and the IRF group (OR 1.90, 95 %CI 1.21–3.23, P = 0.02) when adjusting for age, gender, obesity, diabetes, hypertension, waist circumference, drinking, smoking, history of heart disease and stroke, low-density lipoprotein cholesterol and eGFR category. Analysis of the IRF group indicated that relative to the group of TG/HDL-C < 1.60, the group of TG/HDL-C ≥ 2.97 had an increased risk for the decline of eGFR category (OR 1.89, 95 %CI 1.12–3.21, P = 0.02) and > 30 % decline in eGFR (OR 2.56, 95 %CI 1.05–6.38, P = 0.04). Conclusions The high TG/HDL-C ratio was an independent risk factor for declining renal function in the Chinese population.

Passive Smoking Alters Lipid Profiles in Adolescents

PEDIATRICS ◽  
1991 ◽  
Vol 88 (2) ◽  
pp. 259-264 ◽  
Author(s):  
Joseph Feldman ◽  
I. Ronald Shenker ◽  
Michael Nussbaum ◽  
Marc S. Jacobson ◽  
Ruth A. Etzel ◽  
...  
Keyword(s):  
High Density Lipoprotein ◽  
High Density Lipoprotein Cholesterol ◽  
Passive Smoking ◽  
Plasma Lipid ◽  
Density Lipoprotein ◽  
Lipid Profiles ◽  
High Density ◽  
Lipoprotein Cholesterol ◽  
Increased Risk ◽  
Plasma Cotinine

Although cigarette smoking is associated with elevation of plasma lipid levels and changes in lipoprotein distribution, it is not known whether passive smoking is associated with an alteration in lipid profiles. The relation between plasma cotinine, a marker of exposure to tobacco smoke, and lipid profiles was studied in healthy adolescents from a suburban New York high school district who were undergoing preparticipation sports physicals. Forty-four percent of the adolescents reported that one or both parents currently smoked. Eleven percent of the adolescents had plasma cotinine concentrations ≥2.5 ng/mL, the level considered indicative of exposure. Adolescents with two smoking parents had significantly higher plasma cotinine concentrations after adjustment for other factors than adolescents whose parents did not smoke. Plasma cotinine concentration ≥2.5 ng/mL was associated with an 8.9% greater ratio of total cholesterol to high-density lipoprotein cholesterol (P &lt; .003) and a 6.8% lower high-density lipoprotein cholesterol (P &lt; .03). These results suggest that passive smoking, like active smoking, leads to alterations in lipid profiles predictive of an increased risk of atherosclerosis.

Triglyceride to high density lipoprotein cholesterol ratio, total cholesterol to high density lipoprotein cholesterol ratio and low ankle brachial index in an elderly population

VASA ◽  
2014 ◽  
Vol 43 (3) ◽  
pp. 189-197 ◽  
Author(s):  
Yiqiang Zhan ◽  
Jinming Yu ◽  
Rongjing Ding ◽  
Yihong Sun ◽  
Dayi Hu
Keyword(s):  
High Density Lipoprotein ◽  
Total Cholesterol ◽  
High Density Lipoprotein Cholesterol ◽  
Ankle Brachial Index ◽  
Density Lipoprotein ◽  
High Density ◽  
Lipoprotein Cholesterol ◽  
Lipid Lowering ◽  
Cholesterol Ratio ◽  
Potential Biomarker

Background: The associations of triglyceride (TG) to high-density lipoprotein cholesterol ratio (HDL‑C) and total cholesterol (TC) to HDL‑C ratio and low ankle brachial index (ABI) were seldom investigated. Patients and methods: A population based cross-sectional survey was conducted and 2982 participants 60 years and over were recruited. TG, TC, HDL‑C, and low-density lipoprotein cholesterol (LDL-C) were assessed in all participants. Low ABI was defined as ABI ≤ 0.9 in either leg. Multiple logistic regression models were applied to study the association between TG/HDL‑C ratio, TC/HDL‑C ratio and low ABI. Results: The TG/HDL‑C ratios for those with ABI > 0.9 and ABI ≤ 0.9 were 1.28 ± 1.20 and 1.48 ± 1.13 (P < 0.0001), while the TC/HDL‑C ratios were 3.96 ± 1.09 and 4.32 ± 1.15 (P < 0.0001), respectively. After adjusting for age, gender, body mass index, obesity, current drinking, physical activity, hypertension, diabetes, lipid-lowering drugs, and cardiovascular disease history, the odds ratios (ORs) with 95 % confidence intervals (CIs) of low ABI for TG/HDL‑C ratio and TC/HDL‑C ratio were 1.10 (0.96, 1.26) and 1.34 (1.14, 1.59) in non-smokers. When TC was further adjusted, the ORs (95 % CIs) were 1.40 (0.79, 2.52) and 1.53 (1.21, 1.93) for TG/HDL‑C ratio and TC/HDL‑C ratio, respectively. Non-linear relationships were detected between TG/HDL‑C ratio and TC/HDL‑C ratio and low ABI in both smokers and non-smokers. Conclusions: TC/HDL‑C ratio was significantly associated with low ABI in non-smokers and the association was independent of TC, TG, HDL‑C, and LDL-C. TC/HDL‑C might be considered as a potential biomarker for early peripheral arterial disease screening.

Relationship of low- and high-density lipoprotein cholesterol with atherosclerosis

2011 ◽  
Vol 31 (2) ◽  
pp. 224-226
Author(s):  
Cheng-cheng YI ◽  
WEN-wen LIU ◽  
Ying-qiu ZHANG ◽  
Zhi-jun GUO ◽  
Xiang-yun WANG ◽  
...  
Keyword(s):  
High Density Lipoprotein ◽  
High Density Lipoprotein Cholesterol ◽  
Density Lipoprotein ◽  
High Density ◽  
Lipoprotein Cholesterol ◽  
Relationship Of
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