Renal function in Antarctic teleost fishes: Serum and urine composition

1975 ◽  
Vol 29 (1) ◽  
pp. 59-70 ◽  
Author(s):  
G. H. Dobbs ◽  
A. L. DeVries
Keyword(s):  
Renal Function ◽  
Teleost Fishes ◽  
Urine Composition ◽  
Serum And Urine

Serum Inorganic Fluoride: Changes Related to Previous Fluoride Intake, Renal Function and Bone Resorption

1980 ◽  
Vol 58 (2) ◽  
pp. 145-152 ◽  
Author(s):  
Christine Waterhouse ◽  
D. Taves ◽  
A. Munzer
Keyword(s):  
Renal Function ◽  
Bone Resorption ◽  
Creatinine Clearance ◽  
Glomerular Filtration ◽  
Fluoride Concentration ◽  
Human Organism ◽  
Inorganic Fluoride ◽  
Fluoride Intake ◽  
Urine Specimens ◽  
Serum And Urine

1. Inorganic fluoride concentrations were determined in serum and urine specimens of 24 subjects receiving a standardized low fluoride intake. Serum fluoride was directly correlated with previous intake and appeared to reflect bone fluoride stores. 2. A positive correlation between creatinine and fluoride clearance was found. However, striking reductions in fluoride clearance, which resulted in increases in serum fluoride, were not usually seen until the creatinine clearance was below 25 ml/min. 3. Parathormone produced an increase in serum fluoride and thyrocalcitonin a decrease, probably by their action on bone. 4. Six patients with chronic increased bone resorption had elevated fluoride concentrations. In five, when treatment was successful, serum fluoride fell. Interpretation of the data from this group of patients is complicated by initially low filtration rates associated with hypercalcaemia and hypercalciuria. 5. The sensitivity of the serum fluoride concentration to previous intake, glomerular filtration and the intensity of bone resorption suggests that the human organism exerts no direct homeostatic control over this ion.

Hematology, serum, and urine composition

2021 ◽  
pp. 151-163
Author(s):  
R. Stimmelmayr ◽  
Lara Horstmann ◽  
Brian T. Person ◽  
J.C. George
Keyword(s):  
Urine Composition ◽  
Serum And Urine

scholarly journals Effect of renal function on serum nitrogen oxide concentrations

1996 ◽  
Vol 42 (3) ◽  
pp. 440-444 ◽  
Author(s):  
I M Mackenzie ◽  
A Ekangaki ◽  
J D Young ◽  
C S Garrard
Keyword(s):  
Nitric Oxide ◽  
Renal Function ◽  
Nitrogen Oxide ◽  
Intensive Therapy ◽  
Oxidation Products ◽  
Renal Elimination ◽  
Nitric Oxide Production ◽  
Intensive Therapy Unit ◽  
Serum And Urine

Abstract Nitric oxide is too short-lived to measure in vivo, but its production can be estimated by measuring its stable oxidation products, nitrites and nitrates, in serum. Renal elimination of these ions has been demonstrated, but the effect of renal function on their concentrations in serum is currently unknown. We evaluated serum and urine nitrates + nitrites as serum nitrogen oxides (sNOx), nitrogen oxide (NOx) clearance, and creatinine clearance in 71 patients on the Intensive Therapy Unit. The correlation between sNOx and plasma creatinine was strong and highly significant (P <0.001). These results suggest that renal function has a significant effect on sNOx concentrations. Studies in which the sNOx concentration is used as an index of nitric oxide production can therefore be interpreted only if renal function has been taken into account.

scholarly journals Detection of Aflatoxin B1 among Early and Middle Childhood Iraqi Patients

2020 ◽  
Vol 17 (2(SI)) ◽  
pp. 0604
Author(s):  
Muna AL-Musawi et al.
Keyword(s):  
Renal Function ◽  
Liver Function ◽  
Middle Childhood ◽  
Aflatoxin B1 ◽  
Age Groups ◽  
The Other ◽  
Positive Results ◽  
Control Samples ◽  
Serum And Urine ◽  
Apparently Healthy

      The study was conducted for the detection of Aflatoxin B1(AFB1) in the serum and urine of 42 early and middle childhood patients (26 male and  16 female ) with renal function disease, liver function disease, in additional to atrophy in the growth and other symptoms depending on the information within consent obtained from each patient, in addition to 8 children, apparently healthy, as  the control. The technique of HPLC was used for the detection of AFB1 from all samples. The results showed that out of 42 patient children, 19 (45.2%) gave positive detection of AFB1 in the serum among all age groups patients with a mean of 0.88 ng/ml and a range of (0.12-3.04) ng/ml. This was compared with the control that did not detect any level. On the other hand, AFB1 was not detected in any of urine samples in both of the sexes. Positive results of serum AFB1 were recorded in males more than females sample which reached 12(46.1%) and 7(43.7%) respectively with a mean/ range reached to (1.08 /0.12-2.91 and 0.82/0.12-1.30)ng/ml respectively, compared with 8 control samples that did not detect any value of aflatoxins.

Cardiac troponin I in cats with compromised renal function

2018 ◽  
Vol 21 (10) ◽  
pp. 985-991 ◽  
Author(s):  
Rebecca Langhorn ◽  
Lisbeth R Jessen ◽  
Anne S Kloster ◽  
Anders P Jensen ◽  
Jørgen Koch
Keyword(s):  
Renal Function ◽  
Cardiac Disease ◽  
Cardiac Troponin ◽  
Troponin I ◽  
Cardiac Troponin I ◽  
Control Group ◽  
Healthy Controls ◽  
Serum Cardiac Troponin ◽  
Cardiac Group ◽  
Serum And Urine

ObjectivesCardiac troponins are sensitive and specific markers of myocardial injury. However, their reliability in renal disease has been questioned owing to possible renal involvement in troponin elimination. The primary objective of the present study was to examine whether serum cardiac troponin I is elevated in cats with compromised renal function and no clinically relevant structural cardiac disease. A secondary objective was to examine whether cardiac troponin I is measurable in the urine of cats with normal and compromised renal function.MethodsThis prospective case-control study included 52 cats (19 with compromised renal function, 19 with primary cardiac disease and 14 healthy controls). For all cats, clinical examination, echocardiography, electrocardiography, blood pressure, complete blood count, biochemistry, serum thyroxine and urinalysis were performed. Cardiac troponin I was measured in the serum and urine of each cat.ResultsMedian (range) serum cardiac troponin I concentrations were 0.052 ng/ml (0.015–0.78 ng/ml) for the renal group, 0.083 ng/ml (0.003–3.27 ng/ml) for the cardiac group and 0.012 ng/ml (0.003–0.14 ng/ml) for the control group. The renal and cardiac groups both had significantly higher serum cardiac troponin I concentrations than the control group, whereas no difference could be detected between the renal and cardiac groups. In the renal group 7/19 cats had measurable urine cardiac troponin I, whereas cardiac troponin I was measurable in the urine of one cat in the cardiac group and two healthy controls. There was no significant correlation between serum and urine cardiac troponin I.Conclusions and relevanceElevated serum cardiac troponin I in cats with compromised renal function may occur without evidence of clinically relevant structural cardiac disease. Moreover, detecting cardiac troponin I in urine is most likely in cats with compromised renal function.

Assessment of renal function by serum creatinine and creatinine clearance: glomerular filtration rate estimated by four procedures.

1989 ◽  
Vol 35 (12) ◽  
pp. 2326-2330 ◽  
Author(s):  
F Van Lente ◽  
P Suit
Keyword(s):  
Renal Function ◽  
Glomerular Filtration Rate ◽  
Serum Creatinine ◽  
Creatinine Clearance ◽  
Glomerular Filtration ◽  
Filtration Rate ◽  
Wide Range ◽  
Clear Method ◽  
Serum And Urine

Abstract We compared creatinine concentrations in serum and urine and creatinine clearances determined by two Jaffé (Beckman's "Astra," Boehringer Mannheim Diagnostics) and two enzymatic (Kodak, Boehringer Mannheim Diagnostics) methods. Serum creatinine and creatinine clearances determined by each method were also compared with the glomerular filtration rate as measured with use of sodium [125I]iothalamate in patients with a wide range of renal function. Results between methods correlated excellently, but we saw clear method-dependent biases of up to 2.9 mg/L for serum. The highest serum creatinine values and the lowest creatinine clearances were obtained with Boehringer Mannheim Diagnostics' Jaffé method. The reciprocal of the serum creatinine and the creatinine clearance also correlated well with the glomerular filtration rate, but all methods over-estimated the glomerular filtration rates to varying degrees. Appropriate standardization of methods appears to be as important as method principle for establishing an accurate relationship between creatinine determinations and glomerular filtration rate.

scholarly journals The impact of periodontal disease and dental cleaning procedures on serum and urine kidney biomarkers in dogs and cats

PLoS ONE ◽  
2021 ◽  
Vol 16 (7) ◽  
pp. e0255310
Author(s):  
Jean A. Hall ◽  
Franci J. Forman ◽  
Gerd Bobe ◽  
Giosi Farace ◽  
Murthy Yerramilli
Keyword(s):  
Renal Function ◽  
Kidney Function ◽  
Impaired Renal Function ◽  
Renal Tissue ◽  
Dental Disease ◽  
Cleaning Procedure ◽  
Cystatin B ◽  
Dental Procedures ◽  
Cleaning Procedures ◽  
Serum And Urine

The objective of this study was to evaluate the benefits and inherent risks of dental cleaning procedures, based on serum and urine biomarkers for kidney function and tissue damage, in dogs and cats. Thirty-one asymptomatic, mostly older dogs (14 neutered male and 17 ovariohysterectomized female dogs of various breeds between 3 and 14 years old) and cats (19 neutered male and 12 ovariohysterectomized female domestic short hair cats between 2 and 16 years old) diagnosed with periodontal disease on physical exam, and recommended by their veterinarian to have dental cleaning under general anesthesia were evaluated in a prospective study. Serum and urine samples were collected from dogs and cats 1 week before, 6 hours after, and again 1 week after the dental cleaning procedure. Samples were analyzed for biomarkers of kidney function [serum creatinine (Cr), symmetric dimethylarginine (SDMA), and blood urea nitrogen (BUN), and urine for specific gravity (USG) and protein:creatinine (UPC) ratio]. A panel of biomarkers for renal tissue damage was also assessed [serum β-aminoisobutyric acid (BAIB), and urine cystatin B and clusterin]. Samples collected one week before dental cleaning procedures showed that increased age and severity of dental disease were linked to abnormal kidney function biomarker values (age: elevated SDMA and Cr concentrations and isosthenuric USG values; disease severity: elevated UPC ratios) as well as elevated urine cystatin B and clusterin concentrations. Directly after the dental cleaning procedure, an increased number of cats with elevated SDMA concentrations was observed (specifically in cats with longer duration of dental procedures). Extended duration of dental procedures (≥60 min) was linked to increased urine cystatin B and clusterin concentrations, whereas shorter duration procedures was linked to decreased urine cystatin B and clusterin. Higher SDMA concentrations persisted in cats one week after the dental cleaning procedures and were linked to elevated UPC ratios one week before cleaning procedures. In conclusion, the results of this study indicate a link between severity of dental disease, renal tissue injury, and impaired renal function. Longer duration dental procedures in cats may carry inherent risks of kidney injury and impaired renal function.

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