Visual field decay in normal subjects and in cases of chronic glaucoma

1980 ◽  
Vol 213 (4) ◽  
pp. 291-298 ◽  
Author(s):  
Catharina Holmin ◽  
C. E. T. Krakau
2016 ◽  
Vol 2016 ◽  
pp. 1-9 ◽  
Author(s):  
Pierre-Maxime Lévêque ◽  
Pierre Zéboulon ◽  
Emmanuelle Brasnu ◽  
Christophe Baudouin ◽  
Antoine Labbé

Purpose. To detect changes in optic nerve head (ONH) vascularization in glaucoma patients using spectral-domain OCT angiography (OCT-A).Material and Method. Fifty glaucoma patients and 30 normal subjects were evaluated with OCT-A (AngioVue®, Optovue). The total ONH vessel density and temporal disc vessel density were measured. Clinical data, visual field (VF) parameters, and spectral-domain OCT evaluation (RNFL: retinal nerve fiber layer thickness, GCC: ganglion cell complex thickness, and rim area) were recorded for glaucoma patients. Correlations among total and temporal ONH vessel density and structural and VF parameters were analyzed.Results. In the glaucoma group, total and temporal ONH vessel density were reduced by 24.7% (0.412 versus 0.547;p<0.0001) and 22.88% (0.364 versus 0.472;p=0.001), respectively, as compared with the control group. Univariate analysis showed significant correlation between rim area (mm2) and temporal ONH vessel density (r=0.623;p<0.0001) and total ONH vessel density (r=0.609;p<0.0001). Significant correlations were found between temporal and total ONH vessel density and RNFL, GCC, VF mean deviation, and visual field index.Conclusion. In glaucoma patients OCT-A might detect reduced ONH blood vessel density that is associated with structural and functional glaucomatous damage. OCT-A might become a useful tool for the evaluation of ONH microcirculation changes in glaucoma.


2012 ◽  
Vol 53 (1) ◽  
pp. 118 ◽  
Author(s):  
Joseph Caprioli ◽  
Dennis Mock ◽  
Elena Bitrian ◽  
Abdelmonem Afifi ◽  
Fei Yu ◽  
...  

1984 ◽  
Vol 102 (7) ◽  
pp. 1004-1010 ◽  
Author(s):  
D. F. Ross ◽  
G. A. Fishman ◽  
L. D. Gilbert ◽  
R. J. Anderson

Perception ◽  
1997 ◽  
Vol 26 (1_suppl) ◽  
pp. 11-11 ◽  
Author(s):  
S Trauzettel-Klosinski

The influence of different visual field defects on the reading performance was examined with potential adaptive strategies to improve the reading process in mind. By means of an SLO, the retinal fixation locus (RFL) was determined with the use of single targets and text, and eye movements scanning the text were recorded on video tape. Additionally, eye movements were monitored by an Infrared Limbus Tracker. Visual fields were assessed by the Tübingen Manual and/or automatic perimetry. Normal subjects, and patients with central scotomata, ring scotomata, and hemianopic field defects (HFD) were examined. The main pathological reading parameters were an increase of saccade frequency and regressions per line, and a decrease of reading speed. In patients with field defects involving the visual field centre, fixation behaviour is significant for regaining reading ability. In absolute central scotoma, the lost foveal function promotes eccentric fixation. The remaining problem is insufficient resolution of the RFL, which can be compensated for by magnification of the text. In patients with insufficient size of their reading visual field, due to HFD and ring scotoma, it is crucial that they learn to use a new RFL despite intact foveolar function. Preconditions for reading have been found to be: (1) sufficient resolution of the RFL, (2) a reading visual field of a minimum extent, and (3) intact basic oculomotor function. In patients with visual field defects involving the centre, a sensory-motor adaptation process is required: the use of a new RFL as the new centre of the visual field and as the new zero point for eye-movement coordinates.


1988 ◽  
Vol 66 (3) ◽  
pp. 803-810 ◽  
Author(s):  
Michael P. Rastatter ◽  
Catherine Loren

The current study investigated the capacity of the right hemisphere to process verbs using a paradigm proven reliable for predicting differential, minor hemisphere lexical analysis in the normal, intact brain. Vocal reaction times of normal subjects were measured to unilaterally presented verbs of high and of low frequency. A significant interaction was noted between the stimulus items and visual fields. Post hoc tests showed that vocal reaction times to verbs of high frequency were significantly faster following right visual-field presentations (right hemisphere). No significant differences in vocal reaction time occurred between the two visual fields for the verbs of low frequency. Also, significant differences were observed between the two types of verbs following left visual-field presentation but not the right. These results were interpreted to suggest that right-hemispheric analysis was restricted to the verbs of high frequency in the presence of a dominant left hemisphere.


2004 ◽  
Vol 13 (1) ◽  
pp. 15-21 ◽  
Author(s):  
Michael Wall ◽  
Balwantray Chauhan ◽  
Lars Fris??n ◽  
Philip H. House ◽  
Caridad Brito

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