Activation of tumor necrosis factor — α system in HIV-1 infection: Association with markers of immune activation

Infection ◽  
1995 ◽  
Vol 23 (1) ◽  
pp. 9-15 ◽  
Author(s):  
P. Aukrust ◽  
F. Müller ◽  
S. S. Frøland ◽  
Nina-Beate Liabakk ◽  
T. Espevik
Keyword(s):  
Tumor Necrosis Factor ◽  
Immune Activation ◽  
Tumor Necrosis ◽  
Tumor Necrosis Factor Α ◽  
Factor Α ◽  
Hiv 1 ◽  
Necrosis Factor

scholarly journals Anti-rheumatic compound aurothioglucose inhibits tumor necrosis factor-α-induced HIV-1 replication in latently infected OM10.1 and Ach2 cells

1999 ◽  
Vol 11 (2) ◽  
pp. 143-150 ◽  
Author(s):  
Katrina E. Traber ◽  
Hiroshi Okamoto ◽  
Chieko Kurono ◽  
Masanori Baba ◽  
Claude Saliou ◽  
...  
Keyword(s):  
Tumor Necrosis Factor ◽  
Tumor Necrosis ◽  
Tumor Necrosis Factor Α ◽  
Latently Infected ◽  
Factor Α ◽  
Hiv 1 ◽  
Necrosis Factor

Tumor necrosis factor-α stimulates HIV-1 production in primary culture of human adipocytes

2005 ◽  
Vol 304 (2) ◽  
pp. 544-551 ◽  
Author(s):  
T. Maurin ◽  
C. Saillan-Barreau ◽  
B. Cousin ◽  
L. Casteilla ◽  
A. Doglio ◽  
...  
Keyword(s):  
Tumor Necrosis Factor ◽  
Primary Culture ◽  
Tumor Necrosis ◽  
Tumor Necrosis Factor Α ◽  
Human Adipocytes ◽  
Factor Α ◽  
Hiv 1 ◽  
Necrosis Factor

κ-Opioid Potentiation of Tumor Necrosis Factor-α-Induced Anti-HIV-1 Activity in Acutely Infected Human Brain Cell Cultures

1998 ◽  
Vol 56 (3) ◽  
pp. 397-404 ◽  
Author(s):  
Chun C Chao ◽  
Genya Gekker ◽  
Shuxian Hu ◽  
Fred Kravitz ◽  
Phillip K Peterson
Keyword(s):  
Tumor Necrosis Factor ◽  
Human Brain ◽  
Tumor Necrosis ◽  
Tumor Necrosis Factor Α ◽  
Brain Cell ◽  
Brain Cell Cultures ◽  
Factor Α ◽  
Anti Hiv ◽  
Hiv 1 ◽  
Necrosis Factor

Stability of Tumor Necrosis Factor α, Interleukin 6, and Interleukin 8 in Blood Samples of Patients With Systemic Immune Activation

2008 ◽  
Vol 132 (11) ◽  
pp. 1802-1806 ◽  
Author(s):  
Astrid Friebe ◽  
Hans-Dieter Volk
Keyword(s):  
Tumor Necrosis Factor ◽  
Immune Activation ◽  
Interleukin 6 ◽  
Tumor Necrosis ◽  
Tumor Necrosis Factor Α ◽  
Interleukin 8 ◽  
Test Results ◽  
Systemic Immune Activation ◽  
Factor Α ◽  
Necrosis Factor

Abstract Context.—Tumor necrosis factor α, interleukin 6, and interleukin 8 serum/plasma levels are frequently used for the monitoring of patients with systemic immune activation/ sepsis. This requires comparability of test results over time. However, cytokines are usually not considered to be very stable after blood collection, which might artificially interfere with test results. Objective.—To obtain better knowledge about stability of these cytokines in blood samples for interpretation of test results. Design.—Blood of patients with systemic immune activation was collected in EDTA, lithium heparin, ammonium heparin, and serum tubes. Aliquots were analyzed after storage at room temperature for 2 to 8 hours. Additionally, storage conditions for separated serum/plasma for 24 hours and the reproducibility of repeated cytokine measurements by an automated DPC Immulite analyzer were tested. Results.—Tumor necrosis factor α level was stable in EDTA plasma for 8 hours, while slightly increasing in heparin plasma and serum. Interleukin 6 concentrations were stable for 8 hours in all blood types, whereas interleukin 8 concentrations were stable only in EDTA plasma and were strongly increasing in heparin plasma and serum. Cytokine concentrations in separated serum/plasma were stable during 24 hours if stored at 4°C or frozen at −20 or −70°C. Reproducibility of repeated cytokine measurements revealed no significant differences for all blood types. Conclusions.—Cytokine levels were most critically influenced by the period between blood collection and plasma separation, but its impact was strongly dependent on cytokine and anticoagulant. However, under appropriate conditions cytokine levels were surprisingly stable for up to 8 hours.

Lipopolysaccharide-induced HIV-1 expression in transgenic mice is mediated by tumor necrosis factor-α and interleukin-1, but not by interferon-γ nor interleukin-6

AIDS ◽  
2000 ◽  
Vol 14 (10) ◽  
pp. 1299-1307 ◽  
Author(s):  
Jun Tanaka ◽  
Hidenori Ozaki ◽  
Jiro Yasuda ◽  
Reiko Horai ◽  
Yoichi Tagawa ◽  
...  
Keyword(s):  
Tumor Necrosis Factor ◽  
Transgenic Mice ◽  
Interleukin 6 ◽  
Tumor Necrosis ◽  
Tumor Necrosis Factor Α ◽  
Interleukin 1 ◽  
Interferon Γ ◽  
Factor Α ◽  
Hiv 1 ◽  
Necrosis Factor

TUMOR NECROSIS FACTOR-α DRIVES HIV-1 REPLICATION IN U937 CELL CLONES AND UPREGULATES CXCR4

Cytokine ◽  
2001 ◽  
Vol 13 (1) ◽  
pp. 55-59 ◽  
Author(s):  
Priscilla Biswas ◽  
Barbara Mantelli ◽  
Fanny Delfanti ◽  
Manuela Cota ◽  
Giuliana Vallanti ◽  
...  
Keyword(s):  
Tumor Necrosis Factor ◽  
Tumor Necrosis ◽  
Tumor Necrosis Factor Α ◽  
U937 Cell ◽  
Cell Clones ◽  
Factor Α ◽  
Hiv 1 ◽  
Necrosis Factor
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