Proliferation of Tγ-lymphocytes in two patients: Clinical features and functional properties of the proliferating cells

1982 ◽  
Vol 60 (3) ◽  
pp. 133-142 ◽  
Author(s):  
G. Schlimok ◽  
E. Thiel ◽  
E. P. Rieber ◽  
D. Huhn ◽  
H. Feucht ◽  
...  
Keyword(s):  
Clinical Features ◽  
Functional Properties ◽  
Proliferating Cells ◽  
Tγ Lymphocytes

Do the functional properties of HCN1 mutants correlate with the clinical features in epileptic patients?

2021 ◽  
Author(s):  
Alessandro Porro ◽  
Gerardo Abbandonato ◽  
Valentina Veronesi ◽  
Alberto Russo ◽  
Anna Binda ◽  
...  
Keyword(s):  
Clinical Features ◽  
Functional Properties ◽  
Epileptic Patients

Quaternary structure of Limulus polyphemus hemocyanin

1978 ◽  
Vol 36 (2) ◽  
pp. 176-177
Author(s):  
T. Wichertjes ◽  
E.J. Kwak ◽  
E.F.J. Van Bruggen
Keyword(s):  
Electron Microscopy ◽  
Functional Properties ◽  
Horseshoe Crab ◽  
Temperature Jump ◽  
Quaternary Structure ◽  
Crystallographic Analysis ◽  
Limulus Polyphemus ◽  
Oxygen Binding ◽  
X Ray ◽  
Intact Molecule

Hemocyanin of the horseshoe crab (Limulus polyphemus) has been studied in nany ways. Recently the structure, dissociation and reassembly was studied using electron microscopy of negatively stained specimens as the method of investigation. Crystallization of the protein proved to be possible and X-ray crystallographic analysis was started. Also fluorescence properties of the hemocyanin after dialysis against Tris-glycine buffer + 0.01 M EDTA pH 8.9 (so called “stripped” hemocyanin) and its fractions II and V were studied, as well as functional properties of the fractions by NMR. Finally the temperature-jump method was used for assaying the oxygen binding of the dissociating molecule and of preparations of isolated subunits. Nevertheless very little is known about the structure of the intact molecule. Schutter et al. suggested that the molecule possibly consists of two halves, combined in a staggered way, the halves themselves consisting of four subunits arranged in a square.

Quantitative Model-Based Image Analysis of NuMa Distribution Links Nuclear Organization with Cell Phenotype

2001 ◽  
Vol 7 (S2) ◽  
pp. 578-579
Author(s):  
David W. Knowles ◽  
Sophie A. Lelièvre ◽  
Carlos Ortiz de Solόrzano ◽  
Stephen J. Lockett ◽  
Mina J. Bissell ◽  
...  
Keyword(s):  
Image Analysis ◽  
Mammary Epithelial Cells ◽  
Nuclear Organization ◽  
Critical Role ◽  
Quantitative Model ◽  
Mammary Epithelial ◽  
Cell Phenotype ◽  
Proliferating Cells ◽  
Mitotic Apparatus ◽  
Model Based

The extracellular matrix (ECM) plays a critical role in directing cell behaviour and morphogenesis by regulating gene expression and nuclear organization. Using non-malignant (S1) human mammary epithelial cells (HMECs), it was previously shown that ECM-induced morphogenesis is accompanied by the redistribution of nuclear mitotic apparatus (NuMA) protein from a diffuse pattern in proliferating cells, to a multi-focal pattern as HMECs growth arrested and completed morphogenesis . A process taking 10 to 14 days.To further investigate the link between NuMA distribution and the growth stage of HMECs, we have investigated the distribution of NuMA in non-malignant S1 cells and their malignant, T4, counter-part using a novel model-based image analysis technique. This technique, based on a multi-scale Gaussian blur analysis (Figure 1), quantifies the size of punctate features in an image. Cells were cultured in the presence and absence of a reconstituted basement membrane (rBM) and imaged in 3D using confocal microscopy, for fluorescently labeled monoclonal antibodies to NuMA (fαNuMA) and fluorescently labeled total DNA.

Structural and functional properties of Escherichia coli-derived nucleoplasmin A comparative study of recombinant and natural proteins

2001 ◽  
Vol 268 (6) ◽  
pp. 1739-1748
Author(s):  
Aitor Hierro ◽  
Jesus M. Arizmendi ◽  
Javier De Las Rivas ◽  
M. Angeles Urbaneja ◽  
Adelina Prado ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Comparative Study ◽  
Functional Properties ◽  
Structural And Functional Properties

Solar urticaria. Clinical features and wavelength dependence

1982 ◽  
Vol 118 (4) ◽  
pp. 228-231 ◽  
Author(s):  
M. Ravits
Keyword(s):  
Clinical Features ◽  
Wavelength Dependence ◽  
Solar Urticaria

Fibrosing cholestatic hepatitis: Clinical features, outcome and response to interferon and ribavirin

2001 ◽  
Vol 120 (5) ◽  
pp. A563-A564
Author(s):  
M ISMAIL ◽  
I DABOUL ◽  
B WATERS ◽  
J FLECKENSTEIN ◽  
S VERA ◽  
...  
Keyword(s):  
Clinical Features ◽  
Cholestatic Hepatitis

The clinical features of gallstone disease in heart failure caused by rheumatic heart diseases

2001 ◽  
Vol 120 (5) ◽  
pp. A388-A388
Author(s):  
E BARANSKAYA ◽  
V IVASHKIN
Keyword(s):  
Heart Failure ◽  
Clinical Features ◽  
Heart Diseases ◽  
Gallstone Disease ◽  
Rheumatic Heart
Sign in / Sign up

Export Citation Format

Share Document