In vivo administration of serum thymic factor (FTS) prevents EMC-D virus-induced diabetes and myocarditis in BALB/cAJcl mice

1996 ◽  
Vol 141 (1) ◽  
pp. 73-83 ◽  
Author(s):  
M. Mizutani ◽  
M. El-Fotoh ◽  
M. Mori ◽  
K. Ono ◽  
K. Doi ◽  
...  
Keyword(s):  
Serum Thymic Factor ◽  
Thymic Factor ◽  
In Vivo Administration

Alterations in thymocyte surface markers after in vivo treatment by serum thymic factor

1978 ◽  
Vol 39 (1) ◽  
pp. 47-54 ◽  
Author(s):  
Mireille Dardenne ◽  
Jeannine Charreire ◽  
Jean-François Bach
Keyword(s):  
Surface Markers ◽  
Serum Thymic Factor ◽  
In Vivo Treatment ◽  
Thymic Factor

scholarly journals Activation of Canine Monocytes and Polymorphonuclear Cells by Serum Thymic Factor(FTS) in vivo.

1996 ◽  
Vol 58 (4) ◽  
pp. 323-327 ◽  
Author(s):  
Toshifumi KOSAKA ◽  
Youko NAKADA ◽  
Masayoshi YUKAWA ◽  
Akira AWAYA ◽  
Takashi ONODERA ◽  
...  
Keyword(s):  
Polymorphonuclear Cells ◽  
Serum Thymic Factor ◽  
Thymic Factor

Anticoagulant Properties of Three Mucopolysaccharides Used in Rheumatology

1983 ◽  
Vol 50 (03) ◽  
pp. 652-655 ◽  
Author(s):  
F Bauer ◽  
P Schulz ◽  
G Reber ◽  
C A Bouvier
Keyword(s):  
Factor Xa ◽  
Degenerative Joint Disease ◽  
Joint Disease ◽  
Thrombin Time ◽  
Coagulation Tests ◽  
Amplification System ◽  
Relative Potencies ◽  
In Vivo Administration

SummaryThree mucopolysaccharides (MPS) used in the treatment of degenerative joint disease were compared to heparin to establish their relative potencies on 3 coagulation tests, the aPTT, the antifactor X a activity and the dilute thrombin time. One of the compounds, Arteparon®, was one fourth as potent as heparin on the aPTT, but had little or no influence on the 2 other tests. Further in vitro studies suggested that Arteparon® acted at a higher level than factor Xa generation in the intrinsic amplification system and that its effect was independent of antithrombin III. In vivo administration of Arteparon® confirmed its anticoagulant properties, which raises the question of the clinical use of this MPS.

scholarly journals Calcium uptake of a rat liver microsomal subcellular fraction in response to in vivo administration of carbon tetrachloride.

1976 ◽  
Vol 251 (4) ◽  
pp. 1197-1201 ◽  
Author(s):  
L Moore ◽  
G Rodman Davenport ◽  
E J Landon
Keyword(s):  
Carbon Tetrachloride ◽  
Rat Liver ◽  
Subcellular Fraction ◽  
Calcium Uptake ◽  
In Vivo Administration

scholarly journals Unraveling the In Vivo Protein Corona

Cells ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 132
Author(s):  
Johanna Simon ◽  
Gabor Kuhn ◽  
Michael Fichter ◽  
Stephan Gehring ◽  
Katharina Landfester ◽  
...  
Keyword(s):  
Plasma Proteins ◽  
Ex Vivo ◽  
Protein Corona ◽  
Blood Proteins ◽  
Therapeutic Application ◽  
Complex Situation ◽  
Ex Vivo Approach ◽  
In Vivo Administration

Understanding the behavior of nanoparticles upon contact with a physiological environment is of urgent need in order to improve their properties for a successful therapeutic application. Most commonly, the interaction of nanoparticles with plasma proteins are studied under in vitro conditions. However, this has been shown to not reflect the complex situation after in vivo administration. Therefore, here we focused on the investigation of magnetic nanoparticles with blood proteins under in vivo conditions. Importantly, we observed a radically different proteome in vivo in comparison to the in vitro situation underlining the significance of in vivo protein corona studies. Next to this, we found that the in vivo corona profile does not significantly change over time. To mimic the in vivo situation, we established an approach, which we termed “ex vivo” as it uses whole blood freshly prepared from an animal. Overall, we present a comprehensive analysis focusing on the interaction between nanoparticles and blood proteins under in vivo conditions and how to mimic this situation with our ex vivo approach. This knowledge is needed to characterize the true biological identity of nanoparticles.

Incorporation of 5-Iodouracil labelled with Iodine-131 into the Deoxyribonucleic Acid of Human Leukæmic Leucocytes following in vivo Administration of 5-Iododeoxyuridine labelled with Iodine-131

Nature ◽  
1959 ◽  
Vol 183 (4676) ◽  
pp. 1686-1687 ◽  
Author(s):  
M. L. EIDINOFF ◽  
L. CHEONG ◽  
E. GAMBETTA GURPIDE ◽  
R. S. BENUA ◽  
R. R. ELLISON
Keyword(s):  
Deoxyribonucleic Acid ◽  
Iodine 131 ◽  
In Vivo Administration

scholarly journals Postoperative immuno-gene therapy of murine bladder tumor by in vivo administration of retroviruses expressing mouse interferon-γ

2001 ◽  
Vol 8 (1) ◽  
pp. 73-81 ◽  
Author(s):  
Ai-Li Shiau ◽  
Chih-Yun Lin ◽  
Tzong-Shin Tzai ◽  
Chao-Liang Wu
Keyword(s):  
Gene Therapy ◽  
Bladder Tumor ◽  
Interferon Γ ◽  
In Vivo Administration
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