Proliferative potential of human brain tumours as assessed by nucleolar organizer regions (AgNORs) and Ki67-immunoreactivity

1990 ◽  
Vol 104 (3-4) ◽  
pp. 103-109 ◽  
Author(s):  
K. H. Plate ◽  
J. Rüschoff ◽  
J. Behnke ◽  
H. D. Mennel
Keyword(s):  
Human Brain ◽  
Brain Tumours ◽  
Nucleolar Organizer ◽  
Nucleolar Organizer Regions ◽  
Proliferative Potential ◽  
Human Brain Tumours

Nucleolar organizer regions in various human brain tumors

1991 ◽  
Vol 74 (6) ◽  
pp. 979-984 ◽  
Author(s):  
Tetsuya Shiraishi ◽  
Kazuo Tabuchi ◽  
Toshihiro Mineta ◽  
Nobuaki Momozaki ◽  
Masashi Takagi
Keyword(s):  
Brain Tumors ◽  
Human Brain ◽  
Nucleolar Organizer ◽  
Staining Technique ◽  
Nucleolar Organizer Regions ◽  
Proliferative Potential ◽  
High Grade ◽  
Content Type ◽  
The Mean ◽  
Fine Print

✓ Nucleolar organizer regions (NOR's) are loops of deoxyribonucleic acid (DNA) which transcribe to ribosomal ribonucleic acid (RNA) by RNA polymerase I. They possess vital significance in the ultimate synthesis of cellular proteins. A silver colloid staining technique for demonstration of NOR-associated proteins (Ag-NOR's) was applied to paraffin-embedded sections from 128 varied brain tumors and to chromosomal preparations from cultured brain-tumor cells. There was a statistically significant difference in the mean number of Ag-NOR's per nucleus between low-grade tumors (1.98/nucleus) and high-grade tumors (2.95/nucleus). It is suggested that the mean number of Ag-NOR's may represent the proliferative potential of brain tumors. Furthermore, high-grade tumors usually showed relatively large Ag-NOR's in a scattered distribution. In chromosomal preparations, the cultured cells displayed five to 12 Ag-NOR's on acrocentric chromosomes. Five of eight cell lines examined demonstrated ectopic Ag-NOR's. This simple staining technique can be easily applied to routinely processed paraffin-embedded sections and will become a useful tool for quick estimation of the proliferative potential of human brain tumors.

In vivo magnetic resonance imaging and 31P spectroscopy of large human brain tumours at 1.5 tesla

1988 ◽  
Vol 29 (1) ◽  
pp. 77-82 ◽  
Author(s):  
C. Thomsen ◽  
K. E. Jensen ◽  
E. Achten ◽  
O. Henriksen
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Human Brain ◽  
Brain Tumours ◽  
Resonance Imaging ◽  
Human Brain Tumours

scholarly journals NG2 expression regulates vascular morphology and function in human brain tumours

NeuroImage ◽  
2006 ◽  
Vol 29 (3) ◽  
pp. 965-976 ◽  
Author(s):  
C. Brekke ◽  
A. Lundervold ◽  
P.Ø. Enger ◽  
C. Brekken ◽  
E. Stålsett ◽  
...  
Keyword(s):  
Human Brain ◽  
Brain Tumours ◽  
Vascular Morphology ◽  
Human Brain Tumours ◽  
And Function

The biology of human brain tumours

1979 ◽  
Vol 50 (1-2) ◽  
pp. 7-34 ◽  
Author(s):  
Patricia Kumar
Keyword(s):  
Human Brain ◽  
Brain Tumours ◽  
Human Brain Tumours

Fibrin deposition in primary and metastatic human brain tumours

1996 ◽  
Vol 7 (5) ◽  
pp. 536-548 ◽  
Author(s):  
H. B??rdos ◽  
P. Moln??r ◽  
G. Cs??csei ◽  
R. ??d??ny
Keyword(s):  
Human Brain ◽  
Brain Tumours ◽  
Fibrin Deposition ◽  
Human Brain Tumours

scholarly journals Vidarabin-monophosphate, BCNU, VM26 – an in vitro comparative study of active agents in the treatment of malignant human brain tumours

1987 ◽  
Vol 55 (2) ◽  
pp. 153-158 ◽  
Author(s):  
U Bogdahn ◽  
J Zapf ◽  
H Weber ◽  
G Dünisch ◽  
HG Löbering ◽  
...  
Keyword(s):  
Comparative Study ◽  
Human Brain ◽  
Brain Tumours ◽  
Human Brain Tumours

scholarly journals Diagnostic segregation of human brain tumours using Fourier-transform infrared and/or Raman spectroscopy coupled with discriminant analysis

2013 ◽  
Vol 5 (1) ◽  
pp. 89-102 ◽  
Author(s):  
Ketan Gajjar ◽  
Lara D. Heppenstall ◽  
Weiyi Pang ◽  
Katherine M. Ashton ◽  
Júlio Trevisan ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Fourier Transform ◽  
Discriminant Analysis ◽  
Human Brain ◽  
Brain Tumours ◽  
Fourier Transform Infrared ◽  
Human Brain Tumours
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