Aflatoxin metabolism and absence of cytochrome P-450 in rat colon tissue during vitamin A malnutrition

1978 ◽  
Vol 34 (2) ◽  
pp. 230-232 ◽  
Author(s):  
A. A. Adekunle ◽  
T. C. Campbell ◽  
S. C. Campbell
2005 ◽  
Vol 85 (1) ◽  
pp. 727-734 ◽  
Author(s):  
Yan-Mei Yang ◽  
Dong-Yang Huang ◽  
Ge-Fei Liu ◽  
Jiu-Chang Zhong ◽  
Kun Du ◽  
...  

1973 ◽  
Vol 51 (1) ◽  
pp. 6-11 ◽  
Author(s):  
G. C. Becking

The effect of vitamin A status on hepatic drug metabolism was studied in rats. Animals were fed diets with and without vitamin A for 20 and 25 days. Weight gains of control and deficient animals were not significantly different, whereas liver vitamin A levels had decreased to less than 10% of control animals after 20 days and were essentially zero after eating the deficient diet for 25 days. Aniline metabolism in vitro and aminopyrine metabolism in vitro and in vivo were significantly lower in male weanling rats fed a vitamin A deficient diet for 20 days. No alteration in in vitro p-nitrobenzoic acid metabolism was noted after 25 days on the test. Vitamin A deficiency did not alter microsomal protein levels or cytochrome c reductase activity but deficient animals did have a lower microsomal cytochrome P-450 content. Hepatic enzyme activities and cytochrome P-450 levels were restored to values approaching those found in control animals by feeding vitamin A deficient rats the vitamin A containing diet for 21 days. Liver vitamin A levels were markedly increased after re-feeding studies but were still significantly lower than control animals.


2019 ◽  
Vol 27 (6) ◽  
pp. 1275-1283 ◽  
Author(s):  
Mohsen Chamanara ◽  
Alireza Abdollahi ◽  
Seyed Mahdi Rezayat ◽  
Mamoud Ghazi-Khansari ◽  
Ahmadreza Dehpour ◽  
...  

Author(s):  
E.Yu. Bystrova ◽  
O.N. Platonova ◽  
A.A. Shpanskaya ◽  
K.A. Dvornikova ◽  
A.D. Nozdrachev
Keyword(s):  

2019 ◽  
Vol 41 (6) ◽  
pp. 607-613 ◽  
Author(s):  
Amir Rashidian ◽  
Asma Rashki ◽  
Alireza Abdollahi ◽  
Nazgol-Sadat Haddadi ◽  
Mohsen Chamanara ◽  
...  

2017 ◽  
Vol 10 (1) ◽  
Author(s):  
Crystal L. Whitted ◽  
Victoria E. Palau ◽  
Ruben D. Torrenegra ◽  
Oscar E. Rodriguez ◽  
Sam Harirforoosh

1988 ◽  
Vol 8 (2) ◽  
pp. 187-199
Author(s):  
Igor Ya. Kon' ◽  
Arseny N. Martinchick ◽  
Gennady Yu. Mal'tsev

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