Characterization of a new human diploid cell line—IMR-91

In Vitro ◽  
1983 ◽  
Vol 19 (10) ◽  
pp. 797-804 ◽  
Author(s):  
Warren W. Nichols ◽  
Vincent J. Cristofalo ◽  
Lorraine H. Toji ◽  
Arthur E. Greene ◽  
Margaret M. Aronson ◽  
...  
Keyword(s):  
Cell Line ◽  
Diploid Cell ◽  
Human Diploid Cell ◽  
Diploid Cell Line

Relationship Between Freezing Rate, Ultrastructure and Recovery in a Human Diploid Cell Line

1974 ◽  
Vol 15 (2) ◽  
pp. 419-427
Author(s):  
D. J. BEADLE ◽  
L. W. HARRIS
Keyword(s):  
Cell Line ◽  
Structural Damage ◽  
Diploid Cell ◽  
Freezing Rate ◽  
Human Diploid Cell ◽  
Simple Correlation ◽  
Thaw Cycle ◽  
Freeze Thaw Cycle ◽  
Diploid Cell Line ◽  
The Relationship

The relationship between freezing rate, ultrastructure and recovery in a human diploid cell line has been studied by freezing cells at rates that are known to give high and low recoveries and examining them immediately after thawing. Some correlation was found between structural damage and recovery. The main types of damage observed were loss of cytoplasm and nucleoplasm, indicating disruption of cellular membranes, and swelling of subcellular organelles due to osmotic changes during the freeze-thaw cycle. No simple correlation was found between freezing rate and structural damage. In the absence of a cryoprotectant both rapid and slow freezing produced similar types and amounts of damage resulting in low recovery. In the presence of 10% dimethylsulphoxide, however, slowly frozen cells showed few signs of damage and recovery was high. DMSO had no such protective effect on rapidly frozen cells.

Changes of enzymic activities in human diploid cell line WI-38 at various passages

1970 ◽  
Vol 61 (2-3) ◽  
pp. 357-364 ◽  
Author(s):  
K.-M. Wang ◽  
N.R. Rose ◽  
E.A. Bartholomew ◽  
M. Balzer ◽  
K. Berde ◽  
...  
Keyword(s):  
Cell Line ◽  
Diploid Cell ◽  
Human Diploid Cell ◽  
Diploid Cell Line

Initiation and characterization of a diploid cell line from larval tissues ofAedes dorsalis (Meigen)

In Vitro ◽  
1978 ◽  
Vol 14 (3) ◽  
pp. 255-260 ◽  
Author(s):  
Barbara E. Cahoon ◽  
James L. Hardy ◽  
William C. Reeves
Keyword(s):  
Cell Line ◽  
Diploid Cell ◽  
Diploid Cell Line

scholarly journals Comparative study of the immunogenicity in mice and monkeys of an inactivated CA16 vaccine made from a human diploid cell line

2014 ◽  
Vol 10 (5) ◽  
pp. 1266-1273 ◽  
Author(s):  
Erxia Yang ◽  
Chen Cheng ◽  
Ying Zhang ◽  
Jingjing Wang ◽  
Yanchun Che ◽  
...  
Keyword(s):  
Comparative Study ◽  
Cell Line ◽  
Diploid Cell ◽  
Human Diploid Cell ◽  
Diploid Cell Line

Characterization of a new human diploid cell strain, IMR-90

Science ◽  
1977 ◽  
Vol 196 (4285) ◽  
pp. 60-63 ◽  
Author(s):  
W. Nichols ◽  
D. Murphy ◽  
V. Cristofalo ◽  
L. Toji ◽  
A. Greene ◽  
...  
Keyword(s):  
Diploid Cell ◽  
Cell Strain ◽  
Human Diploid Cell ◽  
Human Diploid Cell Strain
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