Structure and upstream region characterization of the human gene encoding rod photoreceptor cGMP phosphodiesterase α-subunit

1998 ◽  
Vol 10 (3) ◽  
pp. 235-250 ◽  
Author(s):  
Mohamed K. Mohamed ◽  
Russell E. Taylor ◽  
Douglas S. Feinstein ◽  
Xizhong Huang ◽  
Steven J. Pittler
Keyword(s):  
Human Gene ◽  
Upstream Region ◽  
Rod Photoreceptor ◽  
Gene Encoding ◽  
Α Subunit ◽  
Cgmp Phosphodiesterase

Molecular characterization of human and bovine rod photoreceptor cGMP phosphodiesterase α-subunit and chromosomal localization of the human gene

Genomics ◽  
1990 ◽  
Vol 6 (2) ◽  
pp. 272-283 ◽  
Author(s):  
Steven J. Pittler ◽  
Wolfgang Baehr ◽  
John J. Wasmuth ◽  
David G. McConnell ◽  
Mary S. Champagne ◽  
...  
Keyword(s):  
Molecular Characterization ◽  
Chromosomal Localization ◽  
Human Gene ◽  
Rod Photoreceptor ◽  
Α Subunit ◽  
Cgmp Phosphodiesterase

Cloning and characterization of the cDNA and gene encoding the γ-subunit of cGMP-phosphodiesterase in canine retinal rod photoreceptor cells

Gene ◽  
1996 ◽  
Vol 181 (1-2) ◽  
pp. 1-5 ◽  
Author(s):  
Weiquan Wang ◽  
Gregory M. Acland ◽  
Gustavo D. Aguirre ◽  
Kunal Ray
Keyword(s):  
Photoreceptor Cells ◽  
Rod Photoreceptor ◽  
Gene Encoding ◽  
Cgmp Phosphodiesterase ◽  
Γ Subunit ◽  
Retinal Rod

Cloning and characterization of the gene encoding the cGMP-phosphodiesterase γ-subunit of human rod photoreceptor cells

Gene ◽  
1994 ◽  
Vol 151 (1-2) ◽  
pp. 297-301 ◽  
Author(s):  
Natik I. Piriev ◽  
Nikolay V. Khramtsov ◽  
Valery M. Lipkin
Keyword(s):  
Photoreceptor Cells ◽  
Rod Photoreceptor ◽  
Gene Encoding ◽  
Cgmp Phosphodiesterase ◽  
Γ Subunit

scholarly journals Characterization of the human gene encoding ADP-ribosylation factor 1, a guanine nucleotide-binding activator of cholera toxin.

1992 ◽  
Vol 267 (13) ◽  
pp. 9028-9034
Author(s):  
C.M. Lee ◽  
R.S. Haun ◽  
S.C. Tsai ◽  
J Moss ◽  
M Vaughan
Keyword(s):  
Cholera Toxin ◽  
Human Gene ◽  
Nucleotide Binding ◽  
Guanine Nucleotide ◽  
Gene Encoding ◽  
Adp Ribosylation ◽  
Guanine Nucleotide Binding ◽  
Adp Ribosylation Factor

scholarly journals The G-Protein α-Subunit GasC Plays a Major Role in Germination in the Dimorphic FungusPenicillium marneffei

Genetics ◽  
2003 ◽  
Vol 164 (2) ◽  
pp. 487-499 ◽  
Author(s):  
Sophie Zuber ◽  
Michael J Hynes ◽  
Alex Andrianopoulos
Keyword(s):  
G Protein ◽  
Germination Rate ◽  
Yeast Cells ◽  
Class Iii ◽  
Temperature Dependent ◽  
Gene Encoding ◽  
Α Subunit ◽  
G Protein Α Subunit ◽  
Opportunistic Human Pathogen

AbstractThe opportunistic human pathogen Penicillium marneffei exhibits a temperature-dependent dimorphic switch. At 25°, multinucleate, septate hyphae that can undergo differentiation to produce asexual spores (conidia) are produced. At 37° hyphae undergo arthroconidiation to produce uninucleate yeast cells that divide by fission. This work describes the cloning of the P. marneffei gasC gene encoding a G-protein α-subunit that shows high homology to members of the class III fungal Gα-subunits. Characterization of a ΔgasC mutant and strains carrying a dominant-activating gasCG45R or a dominant-interfering gasCG207R allele show that GasC is a crucial regulator of germination. A ΔgasC mutant is severely delayed in germination, whereas strains carrying a dominant-activating gasCG45R allele show a significantly accelerated germination rate. Additionally, GasC signaling positively affects the production of the red pigment by P. marneffei at 25° and negatively affects the onset of conidiation and the conidial yield, showing that GasC function overlaps with functions of the previously described Gα-subunit GasA. In contrast to the S. cerevisiae ortholog Gpa2, our data indicate that GasC is not involved in carbon or nitrogen source sensing and plays no major role in either hyphal or yeast growth or in the switch between these two forms.

Chromosomal localization and preliminary characterization of the human gene encoding insulin-like growth factor II

1985 ◽  
Vol 69 (2) ◽  
pp. 170-173 ◽  
Author(s):  
P. de Pagter-Holthuizen ◽  
J. W. M. Höppener ◽  
M. Jansen ◽  
A. H. M. Geurts van Kessel ◽  
G. J. B. van Ommen ◽  
...  
Keyword(s):  
Growth Factor ◽  
Chromosomal Localization ◽  
Human Gene ◽  
Insulin Like Growth Factor ◽  
Gene Encoding ◽  
Preliminary Characterization ◽  
Factor Ii

Mutations in PDE6A, the Gene Encoding the α-Subunit of Rod Photoreceptor Cgmp-Specific Phosphodiesterase, are Rare in Autosomal Recessive Retinitis Pigmentosa

1997 ◽  
pp. 237-244 ◽  
Author(s):  
M. Meins ◽  
A. Janecke ◽  
C. Marschke ◽  
M. J. Denton ◽  
G. Kumaramanickavel ◽  
...  
Keyword(s):  
Retinitis Pigmentosa ◽  
Autosomal Recessive ◽  
Rod Photoreceptor ◽  
Gene Encoding ◽  
Α Subunit

Molecular characterization of the human gene encoding an abundant 61 kDa protein specific to the retinal pigment epithelium

1995 ◽  
Vol 4 (4) ◽  
pp. 641-649 ◽  
Author(s):  
Aileen Nicoletti ◽  
Deborah J. Wong ◽  
Kazuhide Kawase ◽  
Lisa H. Gibson ◽  
Teresa L. Yang-Feng ◽  
...  
Keyword(s):  
Retinal Pigment Epithelium ◽  
Molecular Characterization ◽  
Human Gene ◽  
Pigment Epithelium ◽  
Retinal Pigment ◽  
Gene Encoding
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