Effect of increasing biliary tract pressure on house rabbit blood dynamics in acute cholangitis of severe type

1994 ◽  
Vol 14 (4) ◽  
pp. 230-234 ◽  
Author(s):  
Zheng Qi-chang ◽  
Qi Li-hang ◽  
Hu You-hua ◽  
Guan Min-lin ◽  
Wang Di-xun

2020 ◽  
pp. 43-47
Author(s):  
A. O. Nekludov ◽  
M. O. Klosova ◽  
O. V. Volchenko ◽  
M. M. Goloborodko ◽  
A. Yu. Korolevska

The main causes of cholangitis are hypertension in the biliary ducts and infection. In order to determine the place of the infectious factor in the acute cholangitis development, a retrospective and prospective analysis of case histories of 176 patients with choledocholithiasis and manifestations of acute and chronic cholangitis was performed. Bile from the common bile duct in the patients with obstruction of the biliary tract was studied. In the patients with mechanical jaundice without and with cholangitis, the intraductal pressure in the common bile duct averaged 227.3±26.1 mm of water column, in the patients without signs of cholangitis that was 97.5±8.3 mm of water column. With mechanical jaundice without acute cholangitis, it was slightly elevated if compared to normal. This suggests that the increase in pressure in the bile ducts in acute cholangitis is not influenced by the fact of obstruction of the biliary tract, and the development of the inflammatory process in them. In the patients with cholangitis, the initial values of the number of colonizing units were much higher than in "pure" choledocholithiasis. After endoscopic papillosphincterotomy in the patients with vivid clinical cholangitis, in whom decompression was achieved, in the control study, this value decreased by 100−500 times, which was accompanied by clinical improvement. According to the results of the study, it was noted that in the patients with a manifested clinic sign of cholangitis there is a significant decrease in the number of colonizing units on the third day after endoscopic papillosphincterotomy. At the stone stuck in a papilla the choledoch turns into so−called analog of an abscess. The opening of the papilla provides a free passage of the contents of the choledochus (i.e. pus) into the duodenum, so there is an almost instant therapeutic effect. The increase in pressure in the bile ducts in acute cholangitis is influenced by the development of an inflammatory process, which indicates the manifestations of biliary infection. The presented research has a prospective character and needs further development. Key words: cholangitis, biliary infection, intraductal pressure, bile.





1998 ◽  
Vol 18 (1) ◽  
pp. 54-57 ◽  
Author(s):  
Zheng Qichang ◽  
Sun Junjun ◽  
Wei Bin ◽  
Hu Youhua




Author(s):  
Luciano HYBNER ◽  
Fernando Issamu TABUSHI ◽  
Luis Martins COLLAÇO ◽  
Érika Gomes DA ROSA ◽  
Bruno de Faria Melquíades DA ROCHA ◽  
...  

ABSTRACT Background: Retrograde endoscopic cholangiopancreatography (ERCP) effectively treats biliary and pancreatic disorders. Its indications are limited and precise, since its misuse delays adequate treatment, increases costs and to patient´s adverse events. Aim: To compare clinical, radiological and exploratory characteristics in relation to therapeutic success in patients undergoing ERCP in relation to age. Method: 421 patients who underwent the method were retrospectively studied; those who were not able to access the duodenal papilla were excluded. The patients were divided into two age groups: <60 years (group 1) and >60 years (group 2), and the variables of gender, examination indications, radiological findings, therapeutic success, diagnosis and the occurrence of immediate adverse events were analyzed. Results: 177 patients were allocated to group 1 and 235 to group 2. The main indication found in both groups was choledocholithiasis. In group 2, the number of cases of acute cholangitis (p=0.001), biliary stenosis (p=0.002) and papilla cancer (p=0.046) was higher. In this group, urgent indication for ERCP was higher (p=0.042), as well as the diagnosis of biliary tract dilatation (p<0.001). The placement of prostheses was the most common procedure performed in both groups, but the greatest number of patients in absolute quantity occurred in group 2. In group 1, the success in catheterization and the chance of achieving clearing of the biliary tract was significantly higher in compared to group 2 (p=0.016, OR=2.1). Conclusion: The success of catheterization and complete clearance of the bile duct was significantly higher in the group of young patients.



1992 ◽  
Vol 75 (2) ◽  
pp. 204???207 ◽  
Author(s):  
H. Krimmer ◽  
R. E. S. Bullingham ◽  
J. Lloyd ◽  
H. P. Bruch




1994 ◽  
Vol 14 (3) ◽  
pp. 181-185
Author(s):  
Zheng Qi-chang ◽  
Ye Jian-yu ◽  
Hu You-hua ◽  
Guan Min-li ◽  
Wang Di-xun


1973 ◽  
Vol 51 (11) ◽  
pp. 859-862 ◽  
Author(s):  
S. M. Strasberg ◽  
C. J. Kooiman ◽  
B. Lomas ◽  
E. B. Johnson ◽  
W. G. Scott ◽  
...  

A new instrument for automatic continuous sampling of bile has been developed. Bile produced by an animal is externally diverted into a reservoir. A detection device permits evacuation of the reservoir into separate chambers, so that a preset continuous sample of total flow is diverted for collection, while the remainder is returned to the animal. The system is closed to air. Biliary tract pressure may be regulated, and bile flow calculated. The apparatus has been found to be very reliable and accurate in over 1 year of use. This instrument is adaptable to sampling other biological liquids.



2020 ◽  
Vol 37 (01) ◽  
pp. 014-023
Author(s):  
Rakesh Navuluri ◽  
Matthew Hoyer ◽  
Murat Osman ◽  
Jonathan Fergus

AbstractAcute pathology of the biliary tract including cholangitis and cholecystitis can lead to biliary sepsis if early decompression is not performed. This article provides an overview of the presenting signs and symptoms and role of interventional radiology in the management of patients with acute cholangitis or acute cholecystitis. It is especially important to understand the role of IR in the context of other treatment options including medical management, endoscopy, and surgery.



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