Serum copper and zinc levels and copper/zinc ratio in patients with breast cancer

1994 ◽  
Vol 40 (1) ◽  
pp. 31-38 ◽  
Author(s):  
Idris Yücel ◽  
Fikret Arpaci ◽  
Ahmet Özet ◽  
Bülent Döner ◽  
Turan Karayilanoĝlu ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Serum Copper ◽  
Copper And Zinc ◽  
Copper Zinc ◽  
Zinc Levels

Serum copper and zinc levels in breast cancer: A meta-analysis

2020 ◽  
Vol 62 ◽  
pp. 126629 ◽  
Author(s):  
Yue Feng ◽  
Jia-Wei Zeng ◽  
Qin Ma ◽  
Shuang Zhang ◽  
Jie Tang ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Meta Analysis ◽  
Serum Copper ◽  
Copper And Zinc ◽  
Zinc Levels

scholarly journals Serum Copper and Zinc Levels and Risk of Hepatocellular Carcinoma: A 1:1 Matched Case-Control Study

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 1397-1397
Author(s):  
Aiping Fang ◽  
Huilian Zhu
Keyword(s):  
Serum Zinc ◽  
Serum Levels ◽  
Case Control ◽  
Serum Copper ◽  
Copper And Zinc ◽  
Copper Zinc ◽  
Matched Case ◽  
Zinc Levels ◽  
Control Study ◽  
Serum Zinc Levels

Abstract Objectives Copper and zinc have been involved in the development of liver cancer in laboratory models, yet data from epidemiological studies are limited. We investigated the association of serum levels of copper and zinc and their ratio with the risk of hepatocellular carcinoma (HCC) in a Chinese population. Methods This is a 1:1 matched case-control study conducted between September 2013 and February 2017. Each case with newly diagnosed HCC from the Guangdong Liver Cancer Cohort (GLCC) was matched to one healthy control from the Guangzhou Nutrition and Health Study by age (±1 years) and sex. Serum copper and zinc levels were quantified using inductively coupled plasma mass spectrometry. Conditional logistic regression models were used to estimate odds ratios (ORs) and 95% confidence intervals (CIs) adjusted for age, sex, body mass index, hepatitis infection, smoking status, alcohol drinking status, diabetes, and chronic inflammation. Serum levels of copper and zinc and their ratio were included in models in tertiles with cutpoints based on the distribution of the control participants. Results A total of 556 case-control pairs were included in this study. Mean (SD) age was 60.3 (7.1) years and 83.8% of the participants were men. HCC cases had significantly higher copper and lower zinc levels, and thus higher copper/zinc, than controls. Higher serum zinc levels were associated with a lower risk of HCC (ORT3 vs T1 = 0.21; 95% CI: 0.07–0.64, P for trend = 0.005). However, there was no association between serum copper levels and HCC risk (ORT3 vs T1 = 1.53; 95% CI: 0.62–3.76, P for trend = 0.375). Higher copper/zinc ratio was associated with increased risk of HCC (ORT3 vs T1 = 3.06; 95% CI: 1.08–8.70, P for trend = 0.049). Conclusions Serum zinc levels were inversely associated with the risk of HCC, suggesting a protective role of zinc in preventing HCC development. Funding Sources This work was supported by the National Natural Science Foundation of China.

Serum Copper and Zinc Levels and Copper/Zinc Ratio in Pediatric Non-Hodgkin’s Lymphoma

1982 ◽  
Vol 67 (1) ◽  
pp. 67-70 ◽  
Author(s):  
S. Gözdaşoğlu ◽  
A.O. Çavdar ◽  
A. Arcasoy ◽  
N. Akar
Keyword(s):  
Hodgkin’S Lymphoma ◽  
Serum Copper ◽  
Hodgkin's Lymphoma ◽  
Copper And Zinc ◽  
Non Hodgkin’S Lymphoma ◽  
Non Hodgkin's Lymphoma ◽  
Copper Zinc ◽  
Zinc Levels

scholarly journals Alterations of Serum Copper and Zinc Levels, and Copper/Zinc Ratios Among Patients with Brucellosis

2012 ◽  
Vol 32 (4) ◽  
pp. 979-983
Author(s):  
Cemal ÜSTÜN ◽  
İbrahim TEĞİN ◽  
Mehmet Faruk GEYİK
Keyword(s):  
Serum Copper ◽  
Copper And Zinc ◽  
Copper Zinc ◽  
Zinc Levels

Analyses of Serum Copper and Zinc Levels and Copper/Zinc Ratios in Skin Diseases

1993 ◽  
Vol 20 (1) ◽  
pp. 21-24 ◽  
Author(s):  
Michiko Tasaki ◽  
Katsumi Hanada ◽  
Isao Hashimoto
Keyword(s):  
Skin Diseases ◽  
Serum Copper ◽  
Copper And Zinc ◽  
Copper Zinc ◽  
Zinc Levels

scholarly journals Serum copper and zinc levels at diagnosis and hepatocellular carcinoma survival in the Guangdong Liver Cancer Cohort

2019 ◽  
Vol 144 (11) ◽  
pp. 2823-2832 ◽  
Author(s):  
Ai‐Ping Fang ◽  
Pei‐Yan Chen ◽  
Xiao‐Yan Wang ◽  
Zhao‐Yan Liu ◽  
Dao‐Ming Zhang ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Cancer ◽  
Serum Copper ◽  
Copper And Zinc ◽  
Zinc Levels

Fetal and maternal serum copper and zinc levels in human pregnancy

1982 ◽  
Vol 2 (5) ◽  
pp. 591-602 ◽  
Author(s):  
I.E. Dreosti ◽  
A.J. McMichael ◽  
G.T. Gibson ◽  
R.A. Buckley ◽  
J.M. Hartshorhe ◽  
...  
Keyword(s):  
Serum Copper ◽  
Maternal Serum ◽  
Human Pregnancy ◽  
Copper And Zinc ◽  
Zinc Levels
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