Serum Copper and Zinc Levels and Colorectal Cancer in Adults: Findings from the National Health and Nutrition Examination 2011–2016

2021 ◽  
Author(s):  
Chaofeng Zhang ◽  
Renqiang Cheng ◽  
Jun Ding ◽  
Xingjia Li ◽  
Hongwen Niu ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
National Health ◽  
Serum Copper ◽  
Health And Nutrition ◽  
Copper And Zinc ◽  
Zinc Levels

Serum Copper and Zinc Levels Among Iranian Colorectal Cancer Patients

2015 ◽  
Vol 170 (2) ◽  
pp. 294-299 ◽  
Author(s):  
Zahra Khoshdel ◽  
Fakhraddin Naghibalhossaini ◽  
Kourosh Abdollahi ◽  
Shahla Shojaei ◽  
Mostafa Moradi ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cancer Patients ◽  
Serum Copper ◽  
Copper And Zinc ◽  
Zinc Levels ◽  
Colorectal Cancer Patients

scholarly journals Serum Alpha-(1, 3)-Fucosyltransferase IV, Copper, and Zinc Levels in Patients with Colorectal Cancer and Healthy Controls

2020 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Roya Abbasi Natajomrani ◽  
Durdi Qujeq ◽  
Vahid Hosseini ◽  
Reza Hajihosseini
Keyword(s):  
Colorectal Cancer ◽  
Clinical Symptoms ◽  
Venous Blood ◽  
Serum Copper ◽  
Enzyme Linked Immunosorbent Assay ◽  
Control Group ◽  
Healthy Controls ◽  
Copper And Zinc ◽  
The Mean ◽  
Zinc Levels

Background: Colorectal cancer (CRC) has no significant clinical symptoms at the early stages, and the molecular differences in the serum of the patients and healthy subjects could be assessed to identify the biological markers that indicate the detection of this cancer at the levels of the biological system. Objectives: The present study aimed to assess the concentrations of the alpha-(1, 3)-fucosyltransferase IV (FUT4) enzyme and copper (Cu) and zinc (Zn) as biological elements. Methods: This case-control study was conducted on 40 patients with CRC, including 20 men and 20 women. A metal-free sterile tube was used to collect five milliliters of venous blood. The enzyme-linked immunosorbent assay (ELISA) based on the Biotin double-antibody sandwich technology was used to measure the human FUT4 in the sera. In addition, plasma zinc and copper values were determined using Zist Chem Diagnostics kits. Results: The mean FUT4 levels in the CRC patients was slightly higher than the control group (P = 0.17), and the mean serum copper and zinc levels of these patients were lower than the control group with a significance difference in this regard (P < 0.001). In addition, the AUC of FUT4, copper, and zinc was 0.58, 0.80, and 0.77, respectively. Conclusions: According to the results, the altered levels of FUT4, copper, and zinc in the serum of the CRC patients compared to the healthy controls could be an indicator associated with the CRC disease course. Furthermore, the unusual changes in the FUT4, copper, and zinc levels may signify CRC development, which plays a key role in the diagnosis and monitoring of this cancer.

Serum copper and zinc levels and copper/zinc ratio in patients with breast cancer

1994 ◽  
Vol 40 (1) ◽  
pp. 31-38 ◽  
Author(s):  
Idris Yücel ◽  
Fikret Arpaci ◽  
Ahmet Özet ◽  
Bülent Döner ◽  
Turan Karayilanoĝlu ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Serum Copper ◽  
Copper And Zinc ◽  
Copper Zinc ◽  
Zinc Levels

scholarly journals The association between serum copper concentrations and elevated blood pressure in US children and adolescents: National Health and Nutrition Examination Survey 2011–2016

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Changsong Liu ◽  
Yanfen Liao ◽  
Zongyuan Zhu ◽  
Lili Yang ◽  
Qin Zhang ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Children And Adolescents ◽  
National Health ◽  
Serum Copper ◽  
Elevated Blood Pressure ◽  
Nutrition Examination Survey ◽  
Elevated Blood ◽  
Cross Sectional ◽  
Health And Nutrition ◽  
Us Children

Abstract Background Copper is an essential trace metal with potential interest for cardiovascular effects. Few studies have explored the association between copper and blood pressure in children and adolescents. Method We conducted a cross-sectional analysis of 1242 children and adolescents aged 8–17 years who participated in the 2011 to 2016 National Health and Nutrition Examination Survey. Using 2017 American Academy of Pediatrics guidelines, elevated blood pressure (EBP) was defined as a mean systolic and/or diastolic blood pressure (BP) ≥ 90th percentile for sex, age, and height for children aged 1–12 years and systolic BP ≥ 120 mmHg or diastolic BP ≥ 80 mmHg for adolescent age 13–17 years. Mean serum copper was 114.17 μg/dL. Results After multiple adjustments, dose–response analyses revealed that EBP was associated with progressively higher serum copper concentrations in a nonlinear trend. In comparison with the lowest quartile of serum copper concentrations, the adjusted odds of EBP for the highest quartile was 5.26 (95% confidence interval, 2.76–10.03). Conclusion Our results suggested that high serum copper concentrations were significantly associated with EBP in US children and adolescents.

scholarly journals Serum copper and zinc levels at diagnosis and hepatocellular carcinoma survival in the Guangdong Liver Cancer Cohort

2019 ◽  
Vol 144 (11) ◽  
pp. 2823-2832 ◽  
Author(s):  
Ai‐Ping Fang ◽  
Pei‐Yan Chen ◽  
Xiao‐Yan Wang ◽  
Zhao‐Yan Liu ◽  
Dao‐Ming Zhang ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Cancer ◽  
Serum Copper ◽  
Copper And Zinc ◽  
Zinc Levels

Fetal and maternal serum copper and zinc levels in human pregnancy

1982 ◽  
Vol 2 (5) ◽  
pp. 591-602 ◽  
Author(s):  
I.E. Dreosti ◽  
A.J. McMichael ◽  
G.T. Gibson ◽  
R.A. Buckley ◽  
J.M. Hartshorhe ◽  
...  
Keyword(s):  
Serum Copper ◽  
Maternal Serum ◽  
Human Pregnancy ◽  
Copper And Zinc ◽  
Zinc Levels

P1518 Serum copper and zinc levels in patients with brucellosis

2007 ◽  
Vol 29 ◽  
pp. S425
Author(s):  
M.F. Geyik ◽  
C. Ustun ◽  
I. Tegin ◽  
S. Hosoglu ◽  
C. Ayaz
Keyword(s):  
Serum Copper ◽  
Copper And Zinc ◽  
Zinc Levels
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