scholarly journals Turning points in time trends of cancer mortality in Japan: Premature mortality is more sensitive in the progress of cancer prevention

2001 ◽  
Vol 5 (4) ◽  
pp. 155-159 ◽  
Author(s):  
Yoshiharu Fukuda ◽  
Keiko Nakamura ◽  
Takehito Takano
2020 ◽  
Author(s):  
Adam Runacres ◽  
Kelly A. Mackintosh ◽  
Melitta A. McNarry

Abstract Introduction Exercise is widely accepted to improve health, reducing the risk of premature mortality, cardiovascular disease (CVD) and cancer. However, several epidemiological studies suggest that the exercise-longevity relationship may be ‘J’ shaped; with elite athlete’s likely training above these intensity and volume thresholds. Therefore, the aim of this meta-analysis was to examine this relationship in former elite athletes. Methods 38,047 English language articles were retrieved from Web of Science, PubMed and SportDiscus databases published after 1970, of which 44 and 24 were included in the systematic review and meta-analysis, respectively. Athletes were split into three groups depending on primary sport: Endurance (END), Mixed/Team, or power (POW). Standard mortality ratio’s (SMR) and standard proportionate mortality ratio (SPMR) were obtained, or calculated, and combined for the meta-analysis. Results Athletes lived significantly longer than the general population (male SMR 0.69 [95% CI 0.61–0.78]; female SMR 0.51 [95% CI 0.40–0.65]; both p < 0.01). There was no survival benefit for male POW athletes compared to the general population (SMR 1.04 [95% CI 0.91–1.12]). Although male athlete’s CVD (SMR 0.73 [95% CI 0.62–0.85]) and cancer mortality (SMR 0.75 [95% CI 0.63–0.89]), were significantly reduced compared to the general population, there was no risk-reduction for POW athletes CVD mortality (SMR 1.10 [0.86–1.40]) or END athletes cancer mortality (SMR 0.73 [0.50–1.07]). There was insufficient data to calculate female sport-specific SMR’s. Discussion Overall, athletes live longer and have a reduced incidence of both CVD and cancer mortality compared to the general population, refuting the ‘J’ shape hypothesis. However, different health risks may be apparent according to sports classification, and between sexes, warranting further investigation. Trial registration PROSPERO (registration number: CRD42019130688).


2010 ◽  
Vol 86 (1017) ◽  
pp. 391-394 ◽  
Author(s):  
E. Pavlidou ◽  
M. Zafrakas ◽  
N. Papadakis ◽  
T. Agorastos ◽  
A. Benos

2016 ◽  
Vol 52 (6) ◽  
pp. 316-320 ◽  
Author(s):  
Juan Carlos Martín-Sánchez ◽  
Ramon Clèries ◽  
Cristina Lidón-Moyano ◽  
Luis González-de Paz ◽  
Jose M. Martínez-Sánchez

2012 ◽  
Vol 36 (4) ◽  
pp. 329-334 ◽  
Author(s):  
Kim P. Wagenaar ◽  
Michiel R. de Boer ◽  
Danièle Luce ◽  
Gwenn Menvielle

2019 ◽  
Vol 177 (3) ◽  
pp. 679-689 ◽  
Author(s):  
Samantha Puvanesarajah ◽  
Susan M. Gapstur ◽  
Alpa V. Patel ◽  
Mark E. Sherman ◽  
W. Dana Flanders ◽  
...  

BMC Cancer ◽  
2013 ◽  
Vol 13 (1) ◽  
Author(s):  
Gonzalo López-Abente ◽  
Montserrat García-Gómez ◽  
Alfredo Menéndez-Navarro ◽  
Pablo Fernández-Navarro ◽  
Rebeca Ramis ◽  
...  
Keyword(s):  

BMC Cancer ◽  
2012 ◽  
Vol 12 (1) ◽  
Author(s):  
Ettore Bidoli ◽  
Lucia Fratino ◽  
Silvia Bruzzone ◽  
Marilena Pappagallo ◽  
Paolo De Paoli ◽  
...  

2018 ◽  
pp. 1-12 ◽  
Author(s):  
Felicia Marie Knaul ◽  
Hector Arreola-Ornelas ◽  
Natalia M. Rodriguez ◽  
Oscar Méndez-Carniado ◽  
Xiaoxiao Jiang Kwete ◽  
...  

Purpose The incidence of infection-associated cancers and lethality of cancers amenable to treatment are closely correlated with the income of countries. We analyzed a core part of this global cancer divide—the distribution of premature mortality across country income groups and cancers—applying novel approaches to measure avoidable mortality and identify priorities for public policy. Methods We analyzed avoidable cancer mortality using set lower- and upper-bound age limits of 65 and 75 years (empirical approach), applying cancer-specific and country income group–specific ages of death (feasibility approach), and applying cancer-specific ages of death of high-income countries to all low- and middle-income countries (LMICs; social justice approach). We applied these methods to 2015 mortality data on 16 cancers for which prevention is possible and/or treatment is likely to result in cure or significant increase in life expectancy. Results At least 30% and as much as 50% of cancer deaths are premature, corresponding to between 2.6 and 4.3 million deaths each year, and 70% to 80% are concentrated in LMICs. Using the feasibility approach, 36% of cancer deaths are avoidable; with the social justice approach, 45% of cancer deaths are avoidable. Five cancer types—breast, colorectal, lung, liver, and stomach—account for almost 75% of avoidable cancer deaths in LMICs and worldwide. Conclusion Each year, millions of premature cancer deaths could be avoided with interventions focused on four priority areas: infection-associated cancers, lifestyle and risk factors, women’s cancers, and children’s cancers. Our analysis of the global burden and the specific cancer types associated with avoidable cancer mortality suggests significant opportunities for health systems to redress the inequity of the global cancer divide.


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