Endogenous induction of transient oxidant-imbalances in Ehrlich cells as a possible trigger to fast tumor fluid accumulation

1995 ◽  
Vol 12 (4) ◽  
pp. 203-207
Author(s):  
Polina M. Schwartsburd ◽  
Vadim Z. Lankin
Keyword(s):  
Fluid Accumulation ◽  
Ehrlich Cells ◽  
Endogenous Induction

Effect of Loperamide on Mucosal Guanylyl Cyclase Activity in Rat Jejunum Following Escherichia coli Heat-Stable Toxin-Induced Fluid Accumulation

2000 ◽  
Vol 86 (2) ◽  
pp. 78-82 ◽  
Author(s):  
Ulrich M. Farack ◽  
Angela Asher ◽  
Bernd Elsenhans ◽  
Barbara Schutte-Luckenga ◽  
Rupert Gerzer
Keyword(s):  
Escherichia Coli ◽  
Guanylyl Cyclase ◽  
Cyclase Activity ◽  
Rat Jejunum ◽  
Fluid Accumulation ◽  
Heat Stable ◽  
Guanylyl Cyclase Activity

Fluid accumulation in the fetal extracerebral spaces: External hydrocephalus or subdural hygromas?

2011 ◽  
Vol 42 (S 01) ◽  
Author(s):  
AE Blank ◽  
A Reitter ◽  
T Heinrich ◽  
F Louwen ◽  
M Mittelbronn ◽  
...  
Keyword(s):  
Fluid Accumulation ◽  
External Hydrocephalus

scholarly journals A Summary of Wellbore Fluid Accumulation and Drainage Gas Production Technology in Gas Wells

2021 ◽  
Vol 621 ◽  
pp. 012113
Author(s):  
Ming Chen ◽  
Junyi Sun ◽  
Ersi Gao ◽  
Haonian Tian
Keyword(s):  
Production Technology ◽  
Gas Production ◽  
Fluid Accumulation ◽  
Gas Wells

scholarly journals Endometrial fluid accumulation in asymptomatic postmenopausal women

1996 ◽  
Vol 8 (1) ◽  
pp. 37-41 ◽  
Author(s):  
M. H. Vuento ◽  
J. P. Pirhonen ◽  
J. I. Mäkinen ◽  
J. E. Tyrkkö ◽  
P. J. Laippala ◽  
...  
Keyword(s):  
Postmenopausal Women ◽  
Fluid Accumulation

Impact of the cystic fibrosis mutation F508del-CFTR on renal cyst formation and growth

2012 ◽  
Vol 303 (8) ◽  
pp. F1176-F1186 ◽  
Author(s):  
Hongyu Li ◽  
Wanding Yang ◽  
Filipa Mendes ◽  
Margarida D. Amaral ◽  
David N. Sheppard
Keyword(s):  
Cystic Fibrosis ◽  
Cell Proliferation ◽  
Mdck Cells ◽  
Ussing Chamber ◽  
Cyst Formation ◽  
Transepithelial Resistance ◽  
Collagen Gels ◽  
Wild Type ◽  
Fluid Accumulation ◽  
The Impact

In autosomal dominant polycystic kidney disease (ADPKD), cystic fibrosis transmembrane conductance regulator (CFTR), the protein product of the gene defective in cystic fibrosis (CF), plays a crucial role in fluid accumulation, which promotes cyst swelling. Several studies have identified individuals afflicted by both ADPKD and CF. Two studies suggested that CF mutations might attenuate the severity of ADPKD, whereas a third found no evidence of a protective effect. In this study, we investigated the impact of the commonest CF mutation F508del-CFTR on the formation and growth of renal cysts. As a model system, we used Madin-Darby canine kidney (MDCK) epithelial cells engineered to express wild-type and F508del human CFTR. We grew MDCK cysts in collagen gels in the presence of the cAMP agonist forskolin and measured transepithelial resistance and Cl− secretion with the Ussing chamber technique and assayed cell proliferation using nonpolarized MDCK cells. When compared with untransfected MDCK cells, cells expressing wild-type CFTR generated substantial numbers of large cysts, which grew markedly over time. By contrast, MDCK cells expressing F508del-CFTR formed very few tiny cysts that failed to enlarge. Interestingly, treatment of F508del-CFTR cysts with the CFTR corrector VRT-325 and the CFTR corrector-potentiator VRT-532 increased the number, but not size, of F508del-CFTR cysts, possibly because VRT-325 inhibited strongly cell proliferation. Based on its effects on transepithelial resistance, Cl− secretion, and cell proliferation, we conclude that the F508del-CFTR mutation disrupts cyst formation and growth by perturbing strongly fluid accumulation within the cyst lumen without compromising epithelial integrity.

scholarly journals Postoperative orbital fluid accumulation masquerading as subperiosteal orbital abscess: A case report and literature review

2014 ◽  
Vol 4 (3) ◽  
pp. 141-143
Author(s):  
Chao-Yun Chi ◽  
Yih-Jeng Tsai ◽  
Cheng-Hui Lin ◽  
Yu-Chi Lin
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Fluid Accumulation ◽  
Orbital Abscess ◽  
Subperiosteal Orbital Abscess

scholarly journals PLEURAL FLUID ACCUMULATION IN CHILDREN WITH UNIVENTRICULAR CONGENITAL HEART DISEASE: THE APPLICATION OF LIGHT'S CRITERIA AFTER THE GLENN AND FONTAN PALLIATION

2013 ◽  
Vol 61 (10) ◽  
pp. E485
Author(s):  
English Flack ◽  
Yvonne Bernard ◽  
Anupama G. Brixey ◽  
Richard W. Light ◽  
Monroe Carell
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Pleural Fluid ◽  
Congenital Heart ◽  
Fluid Accumulation ◽  
Fontan Palliation
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