Early signs of left ventricular dysfunction in adolescents with Type 1 diabetes mellitus: The importance of impaired circadian modulation of blood pressure and heart rate

2008 ◽  
Vol 31 (4) ◽  
pp. 289-296 ◽  
Author(s):  
K. Karavanaki ◽  
G. Kazianis ◽  
I. Konstantopoulos ◽  
E. Tsouvalas ◽  
C. Karayianni
Keyword(s):  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Heart Rate ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Left Ventricular Dysfunction ◽  
Ventricular Dysfunction ◽  
Left Ventricular ◽  
Early Signs

IMPAIRED DIURNAL BLOOD PRESSURE AND HEART RATE VARIATION AND THEIR RELATIONSHIP WITH LEFT-VENTRICULAR FUNCTION IN ADOLESCENTS WITH TYPE 1 DIABETES MELLITUS

PEDIATRICS ◽  
2008 ◽  
Vol 121 (Supplement 2) ◽  
pp. S104.2-S105
Author(s):  
Kyriaki Karavanaki ◽  
George Kazianis ◽  
Emmanouil Tsouvalas ◽  
Ilias Konstantopoulos ◽  
Christina Karayianni
Keyword(s):  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Heart Rate ◽  
Type 1 Diabetes ◽  
Left Ventricular Function ◽  
Type 1 Diabetes Mellitus ◽  
Left Ventricular ◽  
Rate Variation ◽  
Heart Rate Variation

scholarly journals Diagnostic Significance of a Mild Decrease of Baroreflex Sensitivity With Respect to Heart Rate in Type 1 Diabetes Mellitus

2013 ◽  
pp. 605-613
Author(s):  
J. SVAČINOVÁ ◽  
N. HONZÍKOVÁ ◽  
A. KRTIČKA ◽  
I. TONHAJZEROVÁ ◽  
K. JAVORKA ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Heart Rate ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Autonomic Dysfunction ◽  
Baroreflex Sensitivity ◽  
Clinical Signs ◽  
Diagnostic Significance

Decreased baroreflex sensitivity is an early sign of autonomic dysfunction in patients with type-1 diabetes mellitus. We evaluated the repeatability of a mild baroreflex sensitivity decrease in diabetics with respect to their heart rate. Finger blood pressure was continuously recorded in 14 young diabetics without clinical signs of autonomic dysfunction and in 14 age-matched controls for 42 min. The recordings were divided into 3-min segments, and the mean inter-beat interval (IBI), baroreflex sensitivity in ms/mm Hg (BRS) and mHz/mm Hg (BRSf) were determined in each segment. These values fluctuated in each subject within 42 min and therefore coefficients of repeatability were calculated for all subjects. Diabetics compared with controls had a decreased mean BRS (p=0.05), a tendency to a shortened IBI (p=0.08), and a decreased BRSf (p=0.17). IBI correlated with BRS in diabetics (p=0.03); this correlation was at p=0.12 in the controls. BRSf was IBI independent (controls: p=0.81, diabetics: p=0.29). We conclude that BRS is partially dependent on mean IBI. Thus, BRS reflects not only an impairment of the quick baroreflex responses of IBI to blood pressure changes, but also a change of the tonic sympathetic and parasympathetic heart rate control. This is of significance during mild changes of BRS. Therefore, an examination of the BRSf index is highly recommended, because this examination improves the diagnostic value of the measurement, particularly in cases of early signs of autonomic dysfunction.

scholarly journals Renal Hyperfiltration and Systemic Blood Pressure in Patients with Uncomplicated Type 1 Diabetes Mellitus

PLoS ONE ◽  
2013 ◽  
Vol 8 (7) ◽  
pp. e68908 ◽  
Author(s):  
Gary K. Yang ◽  
David M. Maahs ◽  
Bruce A. Perkins ◽  
David Z. I. Cherney
Keyword(s):  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Systemic Blood Pressure ◽  
Systemic Blood ◽  
Renal Hyperfiltration

Heart rate variability and circadian variations in type 1 diabetes mellitus

2006 ◽  
Vol 7 (1) ◽  
pp. 45-50 ◽  
Author(s):  
Firat Kardelen ◽  
Gayaz Akcurin ◽  
Halil Ertug ◽  
Sema Akcurin ◽  
Iffet Bircan
Keyword(s):  
Diabetes Mellitus ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Circadian Variations
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