Spontaneous remission of acromegaly after pituitary apoplexy following head trauma

1988 ◽  
Vol 11 (6) ◽  
pp. 429-432 ◽  
Author(s):  
N. Tamasawa ◽  
K. Kurahashi ◽  
T. Baba ◽  
R. Hishita ◽  
S. Murabayashi ◽  
...  
1995 ◽  
Vol 15 (2) ◽  
pp. 191-192 ◽  
Author(s):  
Mohammed AF Qurttom ◽  
M.S. Seshadri

2015 ◽  
Vol 33 (10) ◽  
pp. 1539.e3-1539.e4 ◽  
Author(s):  
Kamil Kayayurt ◽  
Ömer Lütfi Gündogdu ◽  
Özcan Yavaşi ◽  
Yavuz Metin ◽  
Erhan Ugras

1983 ◽  
Vol 59 (4) ◽  
pp. 677-679 ◽  
Author(s):  
Renn O. Holness ◽  
Fadegbola A. Ogundimu ◽  
Roland A. Langille

✓ The authors report a case of chiasmal compression resulting from hemorrhage into a pituitary adenoma following minor head trauma. The adenoma was still confined to the pituitary fossa and only in retrospect had caused any endocrine effects prior to the accident. The diagnosis in this case was established by computerized tomography, angiography, subsequent surgery, and pathological examination of the specimen. There was significant but partial recovery of vision following surgery.


Author(s):  
E Sanz-Sapera ◽  
S Sarria-Estrada ◽  
F Arikan ◽  
B Biagetti

Summary Pituitary apoplexy is a rare but potentially life-threatening clinical syndrome characterised by ischaemic infarction or haemorrhage into a pituitary tumour that can lead to spontaneous remission of hormonal hypersecretion. We report the case of a 50-year-old man who attended the emergency department for sudden onset of headache. A computed tomography (CT) scan at admission revealed pituitary haemorrhage and the blood test confirmed the clinical suspicion of acromegaly and an associated hypopituitarism. The T1-weighted magnetic resonance imaging (MRI) showed the classic pituitary ring sign on the right side of the pituitary. Following admission, he developed acute-onset hyponatraemia that required hypertonic saline administration, improving progressively. Surprisingly, during the follow-up, IGF1 levels became normal and he progressively recovered pituitary function. Learning points: Patients with pituitary apoplexy may have spontaneous remission of hormonal hypersecretion. If it is not an emergency, we should delay a decision to undertake surgery following apoplexy and re-evaluate hormone secretion. Hyponatraemia is an acute sign of hypocortisolism in pituitary apoplexy. However, SIADH although uncommon, could appear later as a consequence of direct hypothalamic insult and requires active and individualised treatment. For this reason, closely monitoring sodium at the beginning of the episode and throughout the first week is advisable to guard against SIADH. Despite being less frequent, if pituitary apoplexy is limited to the tumour, the patient can recover pituitary function previously damaged by the undiagnosed macroadenoma.


2021 ◽  
Vol 21 (2) ◽  
pp. 194-199
Author(s):  
Sarah Alam ◽  
Suraj Kubihal ◽  
Alpesh Goyal ◽  
Viveka P. Jyotsna

2014 ◽  
Vol 58 (1) ◽  
pp. 76-80 ◽  
Author(s):  
Rocío Villar-Taibo ◽  
María D. Ballesteros-Pomar ◽  
Alfonso Vidal-Casariego ◽  
Rosa M. Álvarez-San Martín ◽  
Georgios Kyriakos ◽  
...  

Pituitary apoplexy is a rare but potentially life-threatening clinical syndrome characterized by ischemic infarction or hemorrhage into a pituitary tumor. The diagnosis of pituitary tumor apoplexy is frequently complicated because of the nonspecific nature of its signs and symptoms, which can mimic different neurological processes, including meningitis. Several factors have been associated with apoplexy, such as dopamine agonists, radiotherapy, or head trauma, but meningitis is a rarely reported cause. We describe the case of a 51-year-old woman with acromegaly due to a pituitary macroadenoma. Before surgical treatment, she arrived at Emergency with fever, nausea, vomiting and meningismus. Symptoms and laboratory tests suggested bacterial meningitis, and antibiotic therapy was initiated, with quick improvement. A computerized tomography (CT) scan at admission did not reveal any change in pituitary adenoma, but a few weeks later, magnetic resonance imaging (MRI) showed data of pituitary apoplexy with complete disappearance of the adenoma. Currently, her acromegaly is cured, but she developed hypopituitarism and diabetes insipidus following apoplexy. We question whether she really experienced meningitis leading to apoplexy or whether apoplexy was misinterpreted as meningitis. In conclusion, the relationship between meningitis and pituitary apoplexy may be bidirectional. Apoplexy can mimic viral or bacterial meningitis, but meningitis might cause apoplexy, as well. This fact highlights the importance of differential diagnosis when evaluating patients with pituitary adenomas and acute neurological symptoms.


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