Automating the Ada binding process for Java — How far can we go?

1998 ◽  
pp. 29-40
Author(s):  
David E. Emery ◽  
Robert F. Mathis ◽  
Karl A. Nyberg
Keyword(s):  
Binding Process

Photophysical Characterisation, Metal Ion Binding and Enantiomeric Recognition of Chiral Ligands Containing Phenazine Fluorophore

2004 ◽  
Vol 69 (4) ◽  
pp. 885-896 ◽  
Author(s):  
Luisa Stella Dolci ◽  
Péter Huszthy ◽  
Erika Samu ◽  
Marco Montalti ◽  
Luca Prodi ◽  
...  
Keyword(s):  
Metal Ion ◽  
Photophysical Properties ◽  
Ion Binding ◽  
Metal Ion Binding ◽  
Ammonium Ions ◽  
Enantiomerically Pure ◽  
Binding Process ◽  
High Affinity ◽  
Enantiomeric Recognition ◽  
Chiral Species

Enantiomerically pure dimethyl- and diisobutyl-substituted phenazino-18-crown-6 ligands bind metal and ammonium ions and also primary aralkylammonium perchlorates in acetonitrile with high affinity, causing pronounced changes in their luminescence properties. In addition, they show enantioselectivity towards chiral primary aralkylammonium perchlorates. The possibility to monitor the binding process by photoluminescence spectroscopy can gain ground for the design of very efficient enantioselective chemosensors for chiral species. The observed changes in the photophysical properties are also an important tool for understanding the interactions present in the adduct.

Topological frustration leading to backtracking in a coupled folding-binding process

2021 ◽  
Author(s):  
Meng Gao ◽  
Ping Li ◽  
Zhengding Su ◽  
Yongqi Huang
Keyword(s):  
Structure Function ◽  
Intrinsically Disordered Proteins ◽  
Disordered Proteins ◽  
Biological Processes ◽  
Sequence Structure ◽  
Binding Process ◽  
Intrinsically Disordered

Intrinsically disordered proteins (IDPs) are abundant in all species. Their discovery challenges the traditional “sequence−structure−function” paradigm of protein science, because IDPs play important roles in various biological processes without preformed...

The influence of intrinsic folding mechanism of an unfolded protein on the coupled folding-binding process during target recognition

2018 ◽  
Vol 87 (4) ◽  
pp. 265-275
Author(s):  
Junwen Xiong ◽  
Meng Gao ◽  
Jingjing Zhou ◽  
Sen Liu ◽  
Zhengding Su ◽  
...  
Keyword(s):  
Target Recognition ◽  
Binding Process ◽  
Unfolded Protein ◽  
Folding Mechanism

Biophysical studies of the interaction between calmodulin and the R287-T311 region of human estrogen receptor α reveals an atypical binding process

2012 ◽  
Vol 419 (2) ◽  
pp. 356-361 ◽  
Author(s):  
Ludovic Carlier ◽  
Cillian Byrne ◽  
Emeric Miclet ◽  
Sandrine Bourgoin-Voillard ◽  
Magali Nicaise ◽  
...  
Keyword(s):  
Estrogen Receptor ◽  
Estrogen Receptor Α ◽  
Binding Process ◽  
Biophysical Studies ◽  
Human Estrogen Receptor

scholarly journals Researches on the Main Characteristics of Red Clover Seedlings and their Influence in

2012 ◽  
Vol 69 (1) ◽  
Author(s):  
Marioara GREBENIȘAN ◽  
Doru PAMFIL ◽  
Dorottya Alice DOMOKOS
Keyword(s):  
Plant Breeding ◽  
Seed Production ◽  
Red Clover ◽  
Production Level ◽  
Seed Crop ◽  
Binding Process ◽  
Lower Variability ◽  
Clover Seed ◽  
Number Of Seeds

Concerning the red clover breeding, it is essential to choose as genitors those varieties that possess good characteristics. In order to identify potential genitors, two red clover varieties were studied at Cluj-Napoca: Roxana, diploid variety and Napoca-tetra, tetraploid variety. The analyzed traits comprised the number of capitula/plant, number of seeds/capitulum and the binding process, under the aspect of their contribution to the seed crop and the interaction between those components, in order to provide important clues about di-and tetraploid red clover seed production, for plant breeding. The highest variability (s%=30) presented regarding the number of flowers/capitulum, diploid variety comparatively with a lower variability (s%=26) regarding the number of flowers number/capitulum, tetraploid varieties. Several traits were compared between di-and tetraploid red clover varieties in order to find genitors which can be used for creating new genotypes with high seed production level.

scholarly journals DOCKING SIMULATIONS ON THE HUMAN beta‐2 ADRENOCEPTOR HELPS TO EXPLAIN THE ENANTIOSELECTIVITY IN BINDING PROCESS.

2009 ◽  
Vol 23 (S1) ◽  
Author(s):  
Jose Correa‐Basurto ◽  
Marvin A Soriano‐Ursúa ◽  
Jose G Trujillo‐Ferrara
Keyword(s):  
Docking Simulations ◽  
Binding Process ◽  
Beta 2

scholarly journals Influence of Me2SO and incubation time on papain activity studied using fluorogenic substrates.

2001 ◽  
Vol 48 (4) ◽  
pp. 995-1002 ◽  
Author(s):  
M Szabelski ◽  
K Stachowiak ◽  
W Wiczk
Keyword(s):  
Incubation Time ◽  
Active Sites ◽  
Initial Rate ◽  
Substrate Binding ◽  
Rapid Decrease ◽  
Fluorogenic Substrates ◽  
Binding Process ◽  
Rate Of Hydrolysis ◽  
Hydrolysis Of

Papain activity in a buffer containing Me2SO was studied using fluorogenic substrates. It was found that the number of active sites of papain decreases with increasing Me2SO concentration whereas the incubation time, in a buffer containing 3% Me2SO does not affect the number of active sites. However, an increase of papain incubation time in the buffer with 3% Me2SO decreased the initial rate of hydrolysis of Z-Phe-Arg-Amc as well as Dabcyl-Lys-Phe-Gly-Gly-Ala-Ala-Edans. Moreover, an increase of Me2SO concentration in working buffer decreased the initial rate of papain-catalysed hydrolysis of both substrates. A rapid decrease of the initial rate (by up to 30%) was observed between 1 and 2% Me2SO. Application of the Michaelis-Menten equation revealed that at the higher Me2SO concentrations the apparent values of k(cat)/Km decreased as a result of Km increase and kcat decrease. However, Me2SO changed the substrate binding process more effectively (Km) than the rate of catalysis k(cat).

A molecular dynamics study of the complete binding process of meropenem to New Delhi metallo-β-lactamase 1

2018 ◽  
Vol 20 (9) ◽  
pp. 6409-6420 ◽  
Author(s):  
Juan Duan ◽  
Chuncai Hu ◽  
Jiafan Guo ◽  
Lianxian Guo ◽  
Jia Sun ◽  
...  
Keyword(s):  
Molecular Dynamics ◽  
Molecular Dynamics Simulations ◽  
Substrate Binding ◽  
New Delhi ◽  
Binding Process ◽  
Dynamics Simulations

We have investigated the substrate-binding pathways of NDM-1 via unbiased molecular dynamics simulations and metadynamics.

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