‘Sausage string’ patterns in blood vessels at high blood pressures

Author(s):  
Preben Alstrøm ◽  
Victor M. Eguíluz ◽  
Finn Gustafsson ◽  
Niels-Henrik Holstein-Rathlou

Author(s):  
P. Alstrøm ◽  
R. Mikkelsen ◽  
F. Gustafsson ◽  
N.-H. Holstein-Rathlou


1999 ◽  
Vol 274 (1-2) ◽  
pp. 111-119
Author(s):  
P. Alstrøm ◽  
R. Mikkelsen ◽  
F. Gustafsson ◽  
N.-H. Holstein-Rathlou


Author(s):  
Jessica E. Wagenseil ◽  
Chris H. Ciliberto ◽  
Russel H. Knutsen ◽  
Marilyn A. Levy ◽  
Attila Kovacs ◽  
...  

Elastin provides reversible extensibility and stores energy during the cardiac cycle in large blood vessels. It is only present in vertebrate animals with a closed circulatory system and high, pulsatile blood pressures. Elastin is crucial for proper cardiac function in vertebrates, as mice lacking elastin (eln-/-) die soon after birth with cardiovascular abnormalities including long, tortuous, stenotic, stiff arteries and high left ventricular (LV) pressure with low cardiac output [1, 2].



2011 ◽  
pp. 70-76
Author(s):  
James R. Munis

Suppose that your heart has just stopped. What would happen to your blood pressure? At least 2 things would happen that you might not predict (and I hope you won't discover them anytime soon). First, the various blood pressures in the different parts of your circulatory system would converge to the same value. Second, you might be surprised to find that your blood pressure is not zero. That's not just because of vertical (hydrostatic) gradients within the body. Because the blood volume is considerably greater than the passive circulatory system volume, the blood vessels are slightly stretched and maintain a non-zero pressure even after the heart stops. To determine the actual non-zero pressure during cardiac arrest, we only have to divide the stressed blood volume by vascular compliance.



Author(s):  
V Nahirniak ◽  
N Kusniak ◽  
I Kashperuk-Karpiuk ◽  
L Andrushchak ◽  
T Protsak ◽  
...  

Background: Previous studies demonstrated a health improving effect in patients underwent an automatic vibratory massage taking 10 minutes. One of reasons that may explain a healing effect of the automatic massage is a stimulated increase in both blood circulation through vascular system and effective size of blood vessels.Objective: This paper aims to quantify a contribution of the automatic mechanical massage of low extremities into the observed reduction in arterial blood pressure and explain this effect.Material and Methods: In this study, the low extremities of male and female patients were exposed to low frequency (12 Hz) mechanical vibrations for 10 minutes and the change in systolic and diastolic arterial blood pressures before and after this procedure was measured.Results: The experiments showed there is a reduction in systolic and diastolic arterial blood pressures after vibrational massage. There were corresponding 3.5±1.8 mmHg and 3.1±1.6 mm Hg arterial blood pressure reductions among men and 5.5±3.2 mm Hg and 2.2±1.2 mm Hg reductions among women.Conclusion: We explained this effect by increasing effective radius of blood vessels. Based on the Hagen-Poiseuille equation, we made estimates for the relative change in the effective radius of blood vessels. They gave the 0.7% and 1.3% increases in the effective radius of blood vessels in low extremities in men during systole and diastole, respectively, and the corresponding 1.1% and 0.6% increases in the effective radius of blood vessels of low extremities in women during the same periods.



2020 ◽  
Author(s):  
Miguel A. Gama Sosa ◽  
Rita De Gasperi ◽  
Gissel M. Perez ◽  
Patrick R. Hof ◽  
Gregory A. Elder


Author(s):  
D. M. DePace

The majority of blood vessels in the superior cervical ganglion possess a continuous endothelium with tight junctions. These same features have been associated with the blood brain barrier of the central nervous system and peripheral nerves. These vessels may perform a barrier function between the capillary circulation and the superior cervical ganglion. The permeability of the blood vessels in the superior cervical ganglion of the rat was tested by intravenous injection of horseradish peroxidase (HRP). Three experimental groups of four animals each were given intravenous HRP (Sigma Type II) in a dosage of.08 to.15 mg/gm body weight in.5 ml of.85% saline. The animals were sacrificed at five, ten or 15 minutes following administration of the tracer. Superior cervical ganglia were quickly removed and fixed by immersion in 2.5% glutaraldehyde in Sorenson's.1M phosphate buffer, pH 7.4. Three control animals received,5ml of saline without HRP. These were sacrificed on the same time schedule. Tissues from experimental and control animals were reacted for peroxidase activity and then processed for routine transmission electron microscopy.



Author(s):  
M.C. Castillo-Jessen ◽  
A. González-Angulo

Information regarding the normal morphology of uterine blood vessels at ultrastructural level in mammals is scarce Electron microscopy studies dealing with endometrial vasculature despite the functional implications due to hormone priming are not available. Light microscopy observations with combined injection of dyes and microradiography along with histochemical studies does not enable us to know the detailed fine structure of the possible various types of blood vessels in this tissue. The present work has been designed to characterize the blood vessels of endometrium of mice as well as the behavior of the endothelium to injection of low molecular weight proteins during the normal estrous cycle in this animal. One hundred and forty female albino mice were sacrificed after intravascular injection of horse radish peroxidase (HRP) at 30 seconds, 5, 15, 30 and 60 minutes.



Author(s):  
Fred E. Hossler

Preparation of replicas of the complex arrangement of blood vessels in various organs and tissues has been accomplished by infusing low viscosity resins into the vasculature. Subsequent removal of the surrounding tissue by maceration leaves a model of the intricate three-dimensional anatomy of the blood vessels of the tissue not obtainable by any other procedure. When applied with care, the vascular corrosion casting technique can reveal fine details of the microvasculature including endothelial nuclear orientation and distribution (Fig. 1), locations of arteriolar sphincters (Fig. 2), venous valve anatomy (Fig. 3), and vessel size, density, and branching patterns. Because casts faithfully replicate tissue vasculature, they can be used for quantitative measurements of that vasculature. The purpose of this report is to summarize and highlight some quantitative applications of vascular corrosion casting. In each example, casts were prepared by infusing Mercox, a methyl-methacrylate resin, and macerating the tissue with 20% KOH. Casts were either mounted for conventional scanning electron microscopy, or sliced for viewing with a confocal laser microscope.



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