Transdifferentiation of Bone Marrow Mesenchymal Stem Cells into the Islet-Like Cells: the Role of Extracellular Matrix Proteins

2015 ◽  
Vol 63 (5) ◽  
pp. 377-384 ◽  
Author(s):  
Marta Pokrywczynska ◽  
Marzena Anna Lewandowska ◽  
Sandra Krzyzanowska ◽  
Arkadiusz Jundzill ◽  
Marta Rasmus ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Extracellular Matrix ◽  
Mesenchymal Stem Cells ◽  
Extracellular Matrix Proteins ◽  
Matrix Proteins ◽  
Marrow Mesenchymal Stem Cells

scholarly journals Updates in the pathophysiological mechanisms of Parkinson’s disease: Emerging role of bone marrow mesenchymal stem cells

2016 ◽  
Vol 8 (3) ◽  
pp. 106 ◽  
Author(s):  
Hanaa H Ahmed ◽  
Ahmed M Salem ◽  
Hazem M Atta ◽  
Emad F Eskandar ◽  
Abdel Razik H Farrag ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Stem Cells ◽  
Bone Marrow ◽  
Parkinson's Disease ◽  
Mesenchymal Stem Cells ◽  
Pathophysiological Mechanisms ◽  
Marrow Mesenchymal Stem Cells

The Regulation of Cellular Adhesion Geometry on Apoptosis of Mesenchymal Stem Cell

2013 ◽  
Vol 378 ◽  
pp. 235-238 ◽  
Author(s):  
Jun Qiu ◽  
Zhuo Zhuang ◽  
Bo Huo
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Extracellular Matrix ◽  
Mesenchymal Stem Cells ◽  
Stem Cell ◽  
Cellular Adhesion ◽  
Tunel Method ◽  
Contact Printing ◽  
Marrow Mesenchymal Stem Cells ◽  
Micro Pattern

The mechanical stimulation from extracellular matrix could regulate physiological behavior of cells through the mechanism of mechanotransduction. Previous researches had shown that apoptosis could be regulated by the size of the cell adhesion area.However, the regulation of cell apoptosis by different adhesion shape with the same area is still unclear. This workfocused on the regulation of apoptosis for bone marrow mesenchymal stem cells (MSCs) by different circularity and area of adhesion geometry. We manufactured micro-pattern surface which was suitable for adhesion of MSCs by the technique of micro-contact printing. Three typesof geometry for individual is land of micro-pattern were designed. We adopted terminal-deoxynucleoitidyl transfer as emediated nick end labeling (TUNEL) method to detectcell apoptosis. This research shows that the adhesion geometry which has smaller area and greater circularity will promote apoptosis of MSCs. This indicates that MSCsmay prefer to live on the surface without any restrict. Ourstudies focused on the significantly important problem about interaction between extracellular matrix and physiological behavior of mesenchymal stem cells.

scholarly journals AMELIORATIVE ROLE OF BONE MARROW MESENCHYMAL STEM CELLS AND RUTIN AGAINST ACETAMINOPHEN INDUCED HEPATOTOXICITY IN ADULT MALE RATS.

2017 ◽  
Vol 5 (9) ◽  
pp. 450-459
Author(s):  
WalaaAMEl Nahrawy ◽  
◽  
FatmaAAbu Zahra ◽  
RabhaEAEL Dab ◽  
◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Adult Male ◽  
Male Rats ◽  
Marrow Mesenchymal Stem Cells

Differentiation of human bone marrow mesenchymal stem cells on decellularized extracellular matrix materials

2013 ◽  
Vol 102 (8) ◽  
pp. 2875-2883 ◽  
Author(s):  
D. M. Hoganson ◽  
A. M. Meppelink ◽  
C. J. Hinkel ◽  
S. M. Goldman ◽  
X.-H. Liu ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Extracellular Matrix ◽  
Mesenchymal Stem Cells ◽  
Human Bone ◽  
Human Bone Marrow ◽  
Decellularized Extracellular Matrix ◽  
Marrow Mesenchymal Stem Cells
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