scholarly journals Modelling the impact of screening for chlamydia and gonorrhoea in youth and other high-prevalence groups in a resource-limited setting

2020 ◽  
Vol 65 (4) ◽  
pp. 413-423
Author(s):  
Rachel T. Esra ◽  
Leigh F. Johnson
2019 ◽  
Vol 49 (2) ◽  
pp. 153-155 ◽  
Author(s):  
Nitin Gupta ◽  
Gagandeep Singh ◽  
Immaculata Xess ◽  
Manish Soneja

Mucormycosis is a potentially fatal fungal infection with high prevalence in poor-resource settings. Besides being an extremely expensive disease to treat, the challenges range from lack of experienced mycologists or mycology department to knowledge and availability of treatment regimes.


Author(s):  
Charles O. Adiri ◽  
Uchenna I. Nwagha ◽  
Tochukwu C. Okeke ◽  
Emmanuel O. Izuka

Gynecological bacterial infections (GBIs) are prevalent in our environment and as a result pose a number of physical, social and psychological consequences. These infections are acquired through several ways. Treating GBIs is a daunting task making its control the most important strategy to alleviating its physical and psychosocial consequences. To highlight the physical, social, and psychological consequences of gynaecological bacterial infections in our resource limited setting. To highlight the hugely unresolved challenges associated with the management of gynecological bacterial infections in our resource-limited setting. Several databases (Medline, Google Scholar, Pubmed, WHO’s Hinari and Wikipedia) and some selected websites were searched using the following keywords: gynecological infections, vaginal infections and discharges, vaginal flora, sexually transmitted infections, pelvic inflammatory disease, syndromic management and challenges, psychosocial consequences, alternative medicine. A total of 5470 relevant articles were obtained between 1947 and 2018. Out of these only 256 relevant articles on the topic were reviewed. However, 213 were dropped for having an incomplete submission. Forty-three (43) articles were fully accessed and referenced. The high prevalence of GBIs poses a lot of burden on the reproductive and socio-economic lives of our women. This should be matched by behavioral changes, prompt diagnosis and early treatment; facilitated by accessible and affordable health care through improved government funding.


BMC Medicine ◽  
2009 ◽  
Vol 7 (1) ◽  
Author(s):  
Marie-Eve Raguenaud ◽  
Petros Isaakidis ◽  
Tony Reid ◽  
Say Chy ◽  
Lim Keuky ◽  
...  

2016 ◽  
Vol 96 (2) ◽  
pp. 488-492 ◽  
Author(s):  
Alastair Stanley ◽  
Bahati M. K. Wajanga ◽  
Hyasinta Jaka ◽  
Rachael Purcell ◽  
Lauren Byrne ◽  
...  

Author(s):  
Cesar Vargas-Serafin ◽  
Aldo A. Acosta-Medina ◽  
Kevin Teran-De-la-Sancha ◽  
Jesus Delgado-de-la-Mora ◽  
María T. Bourlon ◽  
...  

Background: Myelophthisis (MPT) has been associated with a dreadful prognosis. Patients’ access to palliative care (PC) and factors influencing its clinical outcomes are poorly described. Our aim was to analyze the impact of patient- and disease-specific characteristics on survival of patients with MPT and describe their use of PC in a resource-limited setting. Methods: Retrospective study including patients with solid tumor MPT, diagnosed between 1996 and 2018. Results: Seventy patients ( median 58 years) were included. 58% were synchronously diagnosed with MPT at time of primary tumor diagnosis. Most common oncologic diagnoses were prostate (25.7%), gastrointestinal (20%), and breast (18.6%) neoplasms. Median overall survival (OS) was 1.9 months. Primaries other than prostate, breast, and lung (HR 1.37, 95% CI 1.15 - 1.8; p = 0.02) and transfusion requirements (HR 2.8, 95% CI 1.01 – 7.9; p = 0.04) were independently associated with decreased OS. Administration of multiple systemic therapeutic interventions (HR 0.15, 95% CI 0.06 – 0.39; p = 0.01) was the sole factor improving OS. Assessment by PC was pursued in 51.4% of patients. The median number of consults per patient was two, with no difference in assessment rate or consult number across different primaries ( P = 0.96). Four cases of palliative sedation were reported, all performed by the primary care team. Conclusion: MPT is highly heterogeneous and risk stratification to optimize the use of therapeutic interventions in unison with palliative interventions is needed to maximize efforts toward improving patient quality of life. There is an alarming need of PC services in the multidisciplinary management of patients within developing regions.


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