scholarly journals Surviving sepsis campaign: research priorities for sepsis and septic shock

2018 ◽  
Vol 44 (9) ◽  
pp. 1400-1426 ◽  
Author(s):  
Craig M. Coopersmith ◽  
Daniel De Backer ◽  
Clifford S. Deutschman ◽  
Ricard Ferrer ◽  
Ishaq Lat ◽  
...  
Keyword(s):  
Septic Shock ◽  
Research Priorities ◽  
Surviving Sepsis Campaign ◽  
Sepsis And Septic Shock

scholarly journals Management of sepsis and septic shock in the emergency department

2021 ◽  
Author(s):  
Francesco Gavelli ◽  
Luigi Mario Castello ◽  
Gian Carlo Avanzi
Keyword(s):  
Emergency Department ◽  
Septic Shock ◽  
Patient Management ◽  
Emergency Physicians ◽  
Surviving Sepsis Campaign ◽  
Sepsis Management ◽  
Early Management ◽  
New Information ◽  
Sepsis And Septic Shock ◽  
Early Phases

AbstractEarly management of sepsis and septic shock is crucial for patients’ prognosis. As the Emergency Department (ED) is the place where the first medical contact for septic patients is likely to occur, emergency physicians play an essential role in the early phases of patient management, which consists of accurate initial diagnosis, resuscitation, and early antibiotic treatment. Since the issuing of the Surviving Sepsis Campaign guidelines in 2016, several studies have been published on different aspects of sepsis management, adding a substantial amount of new information on the pathophysiology and treatment of sepsis and septic shock. In light of this emerging evidence, the present narrative review provides a comprehensive account of the recent advances in septic patient management in the ED.

scholarly journals Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016

2017 ◽  
Vol 43 (3) ◽  
pp. 304-377 ◽  
Author(s):  
Andrew Rhodes ◽  
Laura E. Evans ◽  
Waleed Alhazzani ◽  
Mitchell M. Levy ◽  
Massimo Antonelli ◽  
...  
Keyword(s):  
Septic Shock ◽  
Surviving Sepsis Campaign ◽  
International Guidelines ◽  
Sepsis And Septic Shock

scholarly journals The Effect of the Intelligent Sepsis Management System on Outcomes among Patients with Sepsis and Septic Shock Diagnosed According to the Sepsis-3 Definition in the Emergency Department

2019 ◽  
Vol 8 (11) ◽  
pp. 1800 ◽  
Author(s):  
Juhyun Song ◽  
Hanjin Cho ◽  
Dae Won Park ◽  
Sejoong Ahn ◽  
Joo Yeong Kim ◽  
...  
Keyword(s):  
Emergency Department ◽  
Septic Shock ◽  
Management System ◽  
Protective Factor ◽  
Causal Effect ◽  
Surviving Sepsis Campaign ◽  
Sepsis Management ◽  
Quasi Experimental ◽  
Sepsis And Septic Shock ◽  
Post Period

We developed a novel computer program, the Intelligent Sepsis Management System, based on Sepsis-3 definitions and 2016 Surviving Sepsis Campaign guidelines and performed a quasi-experimental pre-post study to assess its effect on compliance with the Surviving Sepsis Campaign guidelines and outcomes in patients with sepsis and septic shock. During the pre-period, patients were managed with usual care. During the post-period, patients were managed using the Intelligent Sepsis Management System upon arrival at the emergency department. A total of 631 patients were enrolled (pre-period, 316; post-period, 315). The overall compliance with the Surviving Sepsis Campaign guidelines’ bundle improved (pre-period 10.8% vs. post-period 54.6%; p < 0.001). The post-period showed significantly lower 30-day mortality than the pre-period (pre-period 37.3% vs. post-period 29.5%; p = 0.037), but was not a protective factor for 30-day mortality, with an adjusted hazard ratio (95% confidence interval) of 0.75 (0.55–1.04) (p = 0.151). The associated factors for 30-day mortality were age, sequential organ failure assessment score, overall compliance, and lactate levels. The 30-day mortality was significantly lower in the compliance group than in the non-compliance group (27.2% vs. 36.5%; p = 0.002). After implementation of the Intelligent Sepsis Management System, overall compliance with the Surviving Sepsis Campaign guidelines improved and was associated with reduced 30-day mortality. However, we could not verify the causal effect of this system on 30-day mortality.

scholarly journals Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock, 2012

2013 ◽  
Vol 39 (2) ◽  
pp. 165-228 ◽  
Author(s):  
R. P. Dellinger ◽  
◽  
Mitchell M. Levy ◽  
Andrew Rhodes ◽  
Djillali Annane ◽  
...  
Keyword(s):  
Septic Shock ◽  
Severe Sepsis ◽  
Surviving Sepsis Campaign ◽  
International Guidelines ◽  
Sepsis And Septic Shock

scholarly journals Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021

2021 ◽  
Author(s):  
Laura Evans ◽  
Andrew Rhodes ◽  
Waleed Alhazzani ◽  
Massimo Antonelli ◽  
Craig M. Coopersmith ◽  
...  
Keyword(s):  
Septic Shock ◽  
Surviving Sepsis Campaign ◽  
International Guidelines ◽  
Sepsis And Septic Shock

scholarly journals Clinical conundrums in management of sepsis in the elderly

2015 ◽  
Vol 3 (3) ◽  
pp. 106-112 ◽  
Author(s):  
Vishal Sehgal ◽  
Sukhminder Jit Singh Bajwa ◽  
John A. Consalvo ◽  
Anurag Bajaj
Keyword(s):  
Heart Failure ◽  
Atrial Fibrillation ◽  
Chronic Kidney Disease ◽  
Septic Shock ◽  
Kidney Injury ◽  
The Elderly ◽  
Nutritional Deficiencies ◽  
Surviving Sepsis Campaign ◽  
Clostridium Difficile Colitis ◽  
Sepsis And Septic Shock

Abstract In 2012, surviving sepsis campaign came out with updated international guidelines for management of severe sepsis and septic shock. Paradoxically, there are no specific guidelines for management of sepsis in the elderly, although the elderly are more predisposed to sepsis, and morbidity and mortality related to sepsis. Sepsis in the elderly is, more often than not, complicated by clinical conundrums such as congestive heart failure (CHF), atrial fibrillation (AF), chronic kidney disease (CKD), acute kidney injury (AKI), delirium, dementia, ambulatory dysfunction, polypharmacy, malglycemia, nutritional deficiencies, and antibiotic resistance. Also, with recurrent admissions to the hospital and widespread use of antibiotics, the elderly are more susceptible to Clostridium difficile colitis.

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