Assessment of methylphenidate-induced changes in binding of continuously infused [11C]-raclopride in healthy human subjects: correlation with subjective effects

2005 ◽  
Vol 183 (3) ◽  
pp. 322-330 ◽  
Author(s):  
J. I. Udo de Haes ◽  
R. Kortekaas ◽  
A. Van Waarde ◽  
R. P. Maguire ◽  
J. Pruim ◽  
...  
Author(s):  
Buqing Yi ◽  
Igor Nichiporuk ◽  
Matthias Feuerecker ◽  
Gustav Schelling ◽  
Alexander Chouker

Nutrients ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 618
Author(s):  
Riley Larson ◽  
Courtney Nelson ◽  
Renee Korczak ◽  
Holly Willis ◽  
Jennifer Erickson ◽  
...  

Acacia gum (AG) is a non-viscous soluble fiber that is easily incorporated into beverages and foods. To determine its physiological effects in healthy human subjects, we fed 0, 20, and 40 g of acacia gum in orange juice along with a bagel and cream cheese after a 12 h fast and compared satiety, glycemic response, gastrointestinal tolerance, and food intake among treatments. Subjects (n = 48) reported less hunger and greater fullness at 15 min (p = 0.019 and 0.003, respectively) and 240 min (p = 0.036 and 0.05, respectively) after breakfast with the 40 g fiber treatment. They also reported being more satisfied at 15 min (p = 0.011) and less hungry with the 40 g fiber treatment at 30 min (p = 0.012). Subjects reported more bloating, flatulence, and GI rumbling on the 40 g fiber treatment compared to control, although values for GI tolerance were all low with AG treatment. No significant differences were found in area under the curve (AUC) or change from baseline for blood glucose response, although actual blood glucose with 20 g fiber at 30 min was significantly less than control. Individuals varied greatly in their postprandial glucose response to all treatments. AG improves satiety response and may lower peak glucose response at certain timepoints, and it is well tolerated in healthy human subjects. AG can be added to beverages and foods in doses that can help meet fiber recommendations.


1993 ◽  
Vol 148 (6_pt_1) ◽  
pp. 1571-1575 ◽  
Author(s):  
M. Jeffery Mador ◽  
Ulysses J. Magalang ◽  
Angel Rodis ◽  
Thomas J. Kufel

2006 ◽  
Vol 534 (1-3) ◽  
pp. 280-283 ◽  
Author(s):  
András Dömötör ◽  
János Szolcsányi ◽  
Gyula Mózsik

2014 ◽  
Vol 73 (Suppl 2) ◽  
pp. 222.2-222 ◽  
Author(s):  
J. Voss ◽  
C. Graff ◽  
A. Schwartz ◽  
D. Hyland ◽  
M. Argiriadi ◽  
...  

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