Differential effects of early exposure to alcohol on alcohol preference and blood alcohol levels in low- and high-anxious rats

2020 ◽  
Vol 238 (12) ◽  
pp. 2753-2768
Author(s):  
Renata Ferreira Sgobbi ◽  
Manoel Jorge Nobre
Keyword(s):  
Alcohol Preference ◽  
Blood Alcohol ◽  
Early Exposure ◽  
Differential Effects ◽  
High Anxious ◽  
Blood Alcohol Levels

Blood Alcohol Levels Following Attempted Suicide

1963 ◽  
Vol 24 (1) ◽  
pp. 14-22 ◽  
Author(s):  
I. Pierce James ◽  
D. N. Scott-Orr ◽  
D. H. Curnow
Keyword(s):  
Attempted Suicide ◽  
Blood Alcohol ◽  
Blood Alcohol Levels

High Blood Alcohol Levels in Women

1990 ◽  
Vol 322 (2) ◽  
pp. 95-99 ◽  
Author(s):  
Mario Frezza ◽  
Carlo di Padova ◽  
Gabriele Pozzato ◽  
Maddalena Terpin ◽  
Enrique Baraona ◽  
...  
Keyword(s):  
Blood Alcohol ◽  
Blood Alcohol Levels

Validation of the Alco-Calculator

1975 ◽  
Vol 36 (3) ◽  
pp. 977-978 ◽  
Author(s):  
John V. Compton ◽  
Roger E. Vogler
Keyword(s):  
Confidence Interval ◽  
Blood Alcohol Concentration ◽  
Alcohol Concentration ◽  
Blood Alcohol ◽  
Blood Alcohol Levels

The Alco-calculator was validated by comparing its blood alcohol estimates with actual breath samples (N = 48). The Alco-calculator overestimated the blood alcohol concentration by 20 mg % and showed an accuracy confidence interval of ± 26 mg.% ( p = .95) The utility of the calculator for training in discrimination of blood alcohol levels is discussed.

scholarly journals Ethanol-Related Behaviors in Mouse Lines Selectively Bred for Drinking to Intoxication

2021 ◽  
Vol 11 (2) ◽  
pp. 189
Author(s):  
Bryan E. Jensen ◽  
Kayla G. Townsley ◽  
Kolter B. Grigsby ◽  
Pamela Metten ◽  
Meher Chand ◽  
...  
Keyword(s):  
Drinking Behavior ◽  
Effective Means ◽  
Fixed Ratio ◽  
Progressive Ratio ◽  
Blood Alcohol ◽  
Drinking Patterns ◽  
Self Administration ◽  
Blood Alcohol Levels ◽  
Drinking In The Dark ◽  
Mouse Lines

Alcohol use disorder (AUD) is a devastating psychiatric disorder that has significant wide-reaching effects on individuals and society. Selectively bred mouse lines are an effective means of exploring the genetic and neuronal mechanisms underlying AUD and such studies are translationally important for identifying treatment options. Here, we report on behavioral characterization of two replicate lines of mice that drink to intoxication, the High Drinking in the Dark (HDID)-1 and -2 mice, which have been selectively bred (20+ generations) for the primary phenotype of reaching high blood alcohol levels (BALs) during the drinking in the dark (DID) task, a binge-like drinking assay. Along with their genetically heterogenous progenitor line, Hs/Npt, we tested these mice on: DID and drinking in the light (DIL); temporal drinking patterns; ethanol sensitivity, through loss of righting reflex (LORR); and operant self-administration, including fixed ratio (FR1), fixed ratio 3:1 (FR3), extinction/reinstatement, and progressive ratio (PR). All mice consumed more ethanol during the dark than the light and both HDID lines consumed more ethanol than Hs/Npt during DIL and DID. In the dark, we found that the HDID lines achieved high blood alcohol levels early into a drinking session, suggesting that they exhibit front loading like drinking behavior in the absence of the chronicity usually required for such behavior. Surprisingly, HDID-1 (female and male) and HDID-2 (male) mice were more sensitive to the intoxicating effects of ethanol during the dark (as determined by LORR), while Hs/Npt (female and male) and HDID-2 (female) mice appeared less sensitive. We observed lower HDID-1 ethanol intake compared to either HDID-2 or Hs/Npt during operant ethanol self-administration. There were no genotype differences for either progressive ratio responding, or cue-induced ethanol reinstatement, though the latter is complicated by a lack of extinguished responding behavior. Taken together, these findings suggest that genes affecting one AUD-related behavior do not necessarily affect other AUD-related behaviors. Moreover, these findings highlight that alcohol-related behaviors can also differ between lines selectively bred for the same phenotype, and even between sexes within those same line.

Alcohol and Fatal Road Traffic Accidents

1982 ◽  
Vol 22 (3) ◽  
pp. 189-194 ◽  
Author(s):  
M. Rufus Crompton
Keyword(s):  
Road Traffic Accident ◽  
Traffic Accident ◽  
Traffic Accidents ◽  
Road Traffic ◽  
Blood Alcohol ◽  
Road Traffic Accidents ◽  
Characteristic Distribution ◽  
Road Users ◽  
Blood Alcohol Levels ◽  
Age And Sex

An analysis of 208 cases of immediate death in a road traffic accident in which the blood alcohol was estimated, showed a definite characteristic distribution of varying blood alcohol levels in the various types of road users of differing age and sex.

A Survey of Blood-Alcohol Levels in Self-Poisoning Cases

1988 ◽  
Vol 7 (1) ◽  
pp. 63-69 ◽  
Author(s):  
Rajagopal Varadaraj ◽  
James Mendonca
Keyword(s):  
Blood Alcohol ◽  
Blood Alcohol Levels

Histamine H2 receptor antagonists and blood alcohol levels

1988 ◽  
Vol 33 (6) ◽  
pp. 767-768 ◽  
Author(s):  
G. Holtmann ◽  
M. V. Singer
Keyword(s):  
Blood Alcohol ◽  
Receptor Antagonists ◽  
H2 Receptor Antagonists ◽  
Histamine H2 Receptor ◽  
H2 Receptor ◽  
Blood Alcohol Levels

scholarly journals Alcohol Withdrawal in the Setting of Elevated Blood Alcohol Levels

2006 ◽  
Vol 08 (03) ◽  
pp. 170-173 ◽  
Author(s):  
Joshuah L. Roffman ◽  
Theodore A. Stern
Keyword(s):  
Alcohol Withdrawal ◽  
Blood Alcohol ◽  
Elevated Blood ◽  
Blood Alcohol Levels

Increasing blood alcohol detection and blood alcohol levels in suicidal hanging from 2007 to 2011

Pathology ◽  
2014 ◽  
Vol 46 ◽  
pp. S90
Author(s):  
R. Tse ◽  
R. Lai ◽  
A.D. Cala
Keyword(s):  
Blood Alcohol ◽  
Blood Alcohol Levels
Sign in / Sign up

Export Citation Format

Share Document