The Relationship Between COLI A1 Polymorphisms (Sp 1) and COLI A2 Polymorphisms (Eco R1 and Puv II) with Bone Mineral Density in Chinese Men and Women

2004 ◽  
Vol 75 (2) ◽  
pp. 133-137 ◽  
Author(s):  
E. M. C. Lau ◽  
D. T. K. Choy ◽  
M. Li ◽  
J. Woo ◽  
T. Chung ◽  
...  
Diagnostics ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 938
Author(s):  
Jian Geng ◽  
Ling Wang ◽  
Qing Li ◽  
Pengju Huang ◽  
Yandong Liu ◽  
...  

Little is known about the effect of lumbar intervertebral disc herniation (LDH) on lumbar bone mineral density (BMD), and few previous studies have used quantitative computed tomography (QCT) to assess whether the staging of LDH correlates with lumbar vertebral trabecular volumetric bone mineral density (Trab.vBMD). To explore the relationship between lumbar Trab.vBMD and LDH, seven hundred and fifty-four healthy participants aged 20–60 years were enrolled in the study from an ongoing study on the degeneration of the spine and knee between June 2014 and 2017. QCT was used to measure L2–4 Trab.vBMD and lumbar spine magnetic resonance images (MRI) were performed to assess the incidence of disc herniation. After 9 exclusions, a total of 322 men and 423 women remained. The men and women were divided into younger (age 20–39 years) and older (age 40–60 years) groups and further into those without LDH, with a single LDH segment, and with ≥2 segments. Covariance analysis was used to adjust for the effects of age, BMI, waistline, and hipline on the relationship between Trab.vBMD and LDH. Forty-one younger men (25.0%) and 59 older men (37.3%) had at least one LDH segment. Amongst the women, the numbers were 46 (22.5%) and 80 (36.4%), respectively. Although there were differences in the characteristics data between men and women, the difference in Trab.vBMD between those without LDH and those with single and ≥2 segments was not statistically significant (p > 0.05). These results remained not statistically significant after further adjusting for covariates (p > 0.05). No associations between lumbar disc herniation and vertebral trabecular volumetric bone mineral density were observed in either men or women.


1994 ◽  
Vol 49 (4) ◽  
pp. M189-M194 ◽  
Author(s):  
J. Woo ◽  
E. Lau ◽  
R. Swaminathan ◽  
D. MacDonald ◽  
E. Chan ◽  
...  

Bone ◽  
2019 ◽  
Vol 121 ◽  
pp. 116-120 ◽  
Author(s):  
Yaffah L. Wiegandt ◽  
Per Ejlstrup Sigvardsen ◽  
Mathias H. Sørgaard ◽  
Andreas D. Knudsen ◽  
Sofie Aagaard Rerup ◽  
...  

2012 ◽  
Vol 15 (4) ◽  
pp. 434-442 ◽  
Author(s):  
Wei-Wei Hu ◽  
Hao Zhang ◽  
Chun Wang ◽  
Jie-Mei Gu ◽  
Hua Yue ◽  
...  

2002 ◽  
Vol 13 (3) ◽  
pp. 218-221 ◽  
Author(s):  
E. M. C. Lau ◽  
V. Lam ◽  
M. Li ◽  
K. Ho ◽  
J. Woo

Open Medicine ◽  
2020 ◽  
Vol 15 (1) ◽  
pp. 763-768
Author(s):  
Jianmei Zhang ◽  
Xiaocheng Huang ◽  
Rongbo Yu ◽  
Yan Wang ◽  
Congcong Gao

AbstractBackgroundWhile there is evidence of a link between irisin and bone metabolism, prior clinical evaluations have been limited to women with postmenopausal osteoporosis. The primary goal of this evaluation is to examine the relationship between irisin and bone mineral density (BMD) in geriatric Chinese men experiencing osteoporosis or osteopenia.MethodsIn this case–control study, 43 geriatric Chinese men were verified as having osteoporosis or osteopenia via dual-energy X-ray light absorption spectrophotometry, and 24 subjects were accepted as the controls. Serum irisin levels were detected by a commercial ELISA kit.ResultsSerum irisin levels were lowered in geriatric Chinese men with osteopenia and osteoporosis, and multiple linear regression analysis revealed that the serum irisin level is an independent factor impacting BMD.Conclusions and discussionOur data confirm a positive correlation between irisin levels and BMD in geriatric Chinese men. Irisin has a protective effect on bone health dependent on BMD, but large clinical trials are still required to verify the irisin and BMD relationship.


2013 ◽  
Vol 32 (6) ◽  
pp. 709-717 ◽  
Author(s):  
Won Kim ◽  
Sun G. Chung ◽  
Keewon Kim ◽  
Han Gil Seo ◽  
Byung-Mo Oh ◽  
...  

2006 ◽  
Vol 83 (1) ◽  
pp. 146-154 ◽  
Author(s):  
Yi-Hsiang Hsu ◽  
Scott A Venners ◽  
Henry A Terwedow ◽  
Yan Feng ◽  
Tianhua Niu ◽  
...  

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