scholarly journals Diagnosing fracture-related infections: can we optimize our nuclear imaging techniques?

2019 ◽  
Vol 46 (8) ◽  
pp. 1583-1587
Author(s):  
Andor W. J. M. Glaudemans ◽  
Paul Bosch ◽  
Riemer H. J. A. Slart ◽  
Frank F. A. IJpma ◽  
Geertje A. M. Govaert
2021 ◽  
Vol 15 (1) ◽  
pp. 14
Author(s):  
Nidaa Mikail ◽  
Fabien Hyafil

Infective endocarditis (IE) is a life-threatening disease with stable prevalence despite prophylactic, diagnostic, and therapeutic advances. In parallel to the growing number of cardiac devices implanted, the number of patients developing IE on prosthetic valves and cardiac implanted electronic device (CIED) is increasing at a rapid pace. The diagnosis of IE is particularly challenging, and currently relies on the Duke-Li modified classification, which include clinical, microbiological, and imaging criteria. While echocardiography remains the first line imaging technique, especially in native valve endocarditis, the incremental value of two nuclear imaging techniques, 18F-fluorodeoxyglucose positron emission tomography with computed tomography (18F-FDG-PET/CT) and white blood cells single photon emission tomography with computed tomography (WBC-SPECT), has emerged for the management of prosthetic valve and CIED IE. In this review, we will summarize the procedures for image acquisition, discuss the role of 18F-FDG-PET/CT and WBC-SPECT imaging in different clinical situations of IE, and review the respective diagnostic performance of these nuclear imaging techniques and their integration into the diagnostic algorithm for patients with a suspicion of IE.


2019 ◽  
Vol 53 (4) ◽  
pp. 373-387 ◽  
Author(s):  
Vincenza Granata ◽  
Roberta Fusco ◽  
Sergio Venanzio Setola ◽  
Elisabetta de Lutio di Castelguidone ◽  
Luigi Camera ◽  
...  

Abstract Background Gastroenteropancreatic neuroendocrine tumours (GEP-NETs) are a heterogeneous group of tumours. An effective diagnosis requires a multimodal approach that combines evaluation of clinical symptoms, hormonelevels, radiological and nuclear imaging, and histological confirmation. Imaging plays a critical role in NETs diagnosis, prognosis and management, so the radiologists are important members of the multidisciplinary team. During diagnostic work-up two critical issues are present: firstly the need to identify tumor presence and secondly to define the primary site and assess regional and distant metastases. Conclusions The most appropriate imaging technique depends on the type of neuroendocrine tumour and the availability of specialized imaging techniques and expertise. There is no general consensus on the most efficient imaging pathway, reflecting the challenge in reliably detection of these tumours.


Author(s):  
Ernst E. Van Der Wall ◽  
Menco G. Niemeyer ◽  
Ernest K. J. Pauwels ◽  
Paul R. M. Van Dijkman ◽  
Jakobus A. K. Blokland ◽  
...  

Author(s):  
Aju P. Pazhenkottil ◽  
Ronny R. Buechel

Nuclear imaging was first introduced with the development of scintillator cameras by Hal Anger in the early 1960s. Hence, nuclear imaging is one of the oldest non-invasive imaging techniques in cardiology, beside echocardiography. Over the last few decades, nuclear imaging has seen tremendous advances and has generated great interest as a non-invasive method to assess a variety of medical conditions. Aside from 18F-fluorodeoxyglucose positron emission tomography (PET) for patients with oncological disease, the growth of nuclear medicine in recent years has been mainly driven by the increasing use of single-photon emission computed tomography (SPECT) and PET myocardial perfusion imaging studies in patients with known or suspected coronary artery disease. While SPECT as a non-invasive method is widely available, PET has superior spatial and temporal resolution, allowing quantification of radiotracer uptake and thereby contributing important insights into the pathophysiological regulation of myocardial blood flow and cardiac metabolism.


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