Optimal treatment intensity in children with Down syndrome and myeloid leukaemia: data from 56 children treated on NOPHO-AML protocols and a review of the literature

2006 ◽  
Vol 85 (5) ◽  
pp. 275-280 ◽  
Author(s):  
Lotte Abildgaard ◽  
Eva Ellebæk ◽  
Göran Gustafsson ◽  
Jonas Abrahamsson ◽  
Liisa Hovi ◽  
...  
Keyword(s):  
Down Syndrome ◽  
Myeloid Leukaemia ◽  
Optimal Treatment ◽  
Treatment Intensity ◽  
Review Of The Literature ◽  
Children With Down Syndrome

scholarly journals Investigating the Link Between Trisomy 21 and Acquired Mutations in the GATA1 Gene

The Physician ◽  
2019 ◽  
Vol 6 (1) ◽  
pp. c9
Author(s):  
Triya Chakravorty ◽  
Irene Roberts
Keyword(s):  
Down Syndrome ◽  
Acute Myeloid Leukaemia ◽  
Myeloid Leukaemia ◽  
Trisomy 21 ◽  
Children With Down Syndrome ◽  
Transient Abnormal Myelopoiesis ◽  
Increased Risk ◽  
Leukaemic Cells ◽  
Acute Myeloid

Children with Down syndrome (DS) due to trisomy 21 (T21) are at an increased risk of developing the neonatal preleukaemic disorder transient abnormal myelopoiesis (TAM), which may transform into childhood acute myeloid leukaemia (ML-DS). Leukaemic cells in TAM and ML-DS have acquired mutations in the GATA1 gene. Although it is clear that acquired mutations in GATA1 are necessary for the development of TAM and ML-DS, questions remain concerning the mechanisms of disease.

scholarly journals OC52 A retrospective study of myeloid leukaemia in children with down syndrome in ireland

2019 ◽  
Author(s):  
Gavin P Dowling ◽  
Andrea Piccin ◽  
Katherine T Gavin ◽  
Aengus O’Marcaigh ◽  
Owen P Smith
Keyword(s):  
Down Syndrome ◽  
Retrospective Study ◽  
Myeloid Leukaemia ◽  
Children With Down Syndrome

A retrospective study of myeloid leukaemia in children with Down syndrome in Ireland

2020 ◽  
Vol 189 (3) ◽  
pp. 979-984
Author(s):  
Gavin P. Dowling ◽  
Andrea Piccin ◽  
Katherine T. Gavin ◽  
David R Betts ◽  
Andrea Malone ◽  
...  
Keyword(s):  
Down Syndrome ◽  
Retrospective Study ◽  
Myeloid Leukaemia ◽  
Children With Down Syndrome

Motor Development in Children with Down Syndrome: A Review of the Literature

1991 ◽  
Vol 8 (3) ◽  
pp. 179-209 ◽  
Author(s):  
Martin E. Block
Keyword(s):  
Down Syndrome ◽  
Motor Development ◽  
Future Research ◽  
Medical Conditions ◽  
Review Of The Literature ◽  
Children With Down Syndrome ◽  
Extant Literature ◽  
Sensory Deficits ◽  
The Past ◽  
The Relationship

The effects of Down syndrome (DS) on motor development have been widely reported over the years, particularly with the profusion of research in the past 10 years. Although more research is needed to fully understand the relationship between DS and motor development, there is a need to synthesize the current findings. Henderson (1985, 1986) and Reid (1985) reviewed the literature regarding the motor development of children with DS. While Henderson’s review was extremely well done, certain recent studies can add to our understanding of the motor characteristics of these children. Furthermore, Henderson did not examine factors such as cardiac, anatomical, and sensory deficits that can affect motor development. Therefore this paper reviews the extant literature regarding the motor development of children with DS in terms of health and medical conditions that can affect this development as well as the motor development of infants and all others with DS. Finally, implications for future research and programming are discussed.

scholarly journals Sleep measurement and monitoring in children with Down syndrome: A review of the literature, 1960–2010

2012 ◽  
Vol 16 (5) ◽  
pp. 477-488 ◽  
Author(s):  
Shervin S. Churchill ◽  
Gail M. Kieckhefer ◽  
Carol A. Landis ◽  
Teresa M. Ward
Keyword(s):  
Down Syndrome ◽  
Review Of The Literature ◽  
Children With Down Syndrome ◽  
Sleep Measurement

Myeloid leukaemia in children with down syndrome: Report of the registry-based French experience between 1990 and 2003

2010 ◽  
Vol 54 (7) ◽  
pp. 927-933 ◽  
Author(s):  
Julie Tandonnet ◽  
Jacqueline Clavel ◽  
André Baruchel ◽  
Fabienne Nacka ◽  
Yves Pérel
Keyword(s):  
Down Syndrome ◽  
Myeloid Leukaemia ◽  
Children With Down Syndrome ◽  
French Experience ◽  
Syndrome Report

scholarly journals PF283 A RETROSPECTIVE STUDY OF MYELOID LEUKAEMIA IN CHILDREN WITH DOWN SYNDROME IN IRELAND

HemaSphere ◽  
2019 ◽  
Vol 3 (S1) ◽  
pp. 93
Author(s):  
G.P. Dowling ◽  
A. Piccin ◽  
A. O’Marcaigh ◽  
K.T. Gavin ◽  
A. Malone ◽  
...  
Keyword(s):  
Down Syndrome ◽  
Retrospective Study ◽  
Myeloid Leukaemia ◽  
Children With Down Syndrome
Sign in / Sign up

Export Citation Format

Share Document