Activated Src and Ras induce gefitinib resistance by activation of signaling pathways downstream of epidermal growth factor receptor in human gallbladder adenocarcinoma cells

Baoli Qin; Hiroshi Ariyama; Eishi Baba; Risa Tanaka; Hitoshi Kusaba; Mine Harada; Shuji Nakano

doi:10.1007/s00280-006-0219-4

Activated Src and Ras induce gefitinib resistance by activation of signaling pathways downstream of epidermal growth factor receptor in human gallbladder adenocarcinoma cells

Cancer Chemotherapy and Pharmacology ◽

10.1007/s00280-006-0219-4 ◽

2006 ◽

Vol 58 (5) ◽

pp. 577-584 ◽

Cited By ~ 31

Author(s):

Baoli Qin ◽

Hiroshi Ariyama ◽

Eishi Baba ◽

Risa Tanaka ◽

Hitoshi Kusaba ◽

...

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Signaling Pathways ◽

Growth Factor Receptor ◽

Human Gallbladder ◽

Adenocarcinoma Cells ◽

Epidermal Growth ◽

Gallbladder Adenocarcinoma ◽

Gefitinib Resistance

Download Full-text

Endothelin-1 Stimulates Cyclooxygenase-2 Expression in Ovarian Cancer Cells Through Multiple Signaling Pathways: Evidence for Involvement of Transactivation of the Epidermal Growth Factor Receptor

Journal of Cardiovascular Pharmacology ◽

10.1097/01.fjc.0000166255.12229.0d ◽

2004 ◽

Vol 44 (Supplement 1) ◽

pp. S140-S143 ◽

Cited By ~ 18

Author(s):

Francesca Spinella ◽

Laura Rosan?? ◽

Giacomo Elia ◽

Valeriana Di Castro ◽

Pier Giorgio Natali ◽

...

Keyword(s):

Ovarian Cancer ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Cancer Cells ◽

Signaling Pathways ◽

Growth Factor Receptor ◽

Ovarian Cancer Cells ◽

Epidermal Growth ◽

Multiple Signaling

Download Full-text

Ligand-induced activation of epidermal growth factor receptor in intact rat mammary adenocarcinoma cells without detectable receptor phosphorylation.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)49779-2 ◽

1992 ◽

Vol 267 (17) ◽

pp. 11872-11880

Author(s):

R.B. Lichtner ◽

M Wiedemuth ◽

A Kittmann ◽

A Ullrich ◽

V Schirrmacher ◽

...

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Growth Factor Receptor ◽

Mammary Adenocarcinoma ◽

Receptor Phosphorylation ◽

Adenocarcinoma Cells ◽

Epidermal Growth

Download Full-text

Establishment and biological characteristics of acquired gefitinib resistance in cell line NCI-H1975/gefinitib-resistant with epidermal growth factor receptor T790M mutation

Molecular Medicine Reports ◽

10.3892/mmr.2014.3058 ◽

2014 ◽

Vol 11 (4) ◽

pp. 2767-2774 ◽

Cited By ~ 9

Author(s):

BAO-XIA ZHAO ◽

JING WANG ◽

BO SONG ◽

HONG WEI ◽

WEI-PENG LV ◽

...

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Cell Line ◽

Growth Factor Receptor ◽

Biological Characteristics ◽

T790m Mutation ◽

Epidermal Growth ◽

Gefitinib Resistance

Download Full-text

Sphingosine-1-phosphate receptor-3 signaling up-regulates epidermal growth factor receptor and enhances epidermal growth factor receptor-mediated carcinogenic activities in cultured lung adenocarcinoma cells

International Journal of Oncology ◽

10.3892/ijo.2012.1379 ◽

2012 ◽

Cited By ~ 4

Author(s):

Menq-Jer Lee

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Lung Adenocarcinoma ◽

Growth Factor Receptor ◽

Adenocarcinoma Cells ◽

Sphingosine 1 Phosphate ◽

Epidermal Growth ◽

Lung Adenocarcinoma Cells

Download Full-text

Proteinase-activated Receptor-2 Transactivation of Epidermal Growth Factor Receptor and Transforming Growth Factor-β Receptor Signaling Pathways Contributes to Renal Fibrosis

Journal of Biological Chemistry ◽

10.1074/jbc.m113.492793 ◽

2013 ◽

Vol 288 (52) ◽

pp. 37319-37331 ◽

Cited By ~ 52

Author(s):

Hyunjae Chung ◽

Rithwik Ramachandran ◽

Morley D. Hollenberg ◽

Daniel A. Muruve

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Signaling Pathways ◽

Renal Fibrosis ◽

Transforming Growth Factor ◽

Growth Factor Receptor ◽

Transforming Growth Factor Β ◽

Epidermal Growth ◽

Β Receptor

Download Full-text

High- and Low-Affinity Epidermal Growth Factor Receptor-Ligand Interactions Activate Distinct Signaling Pathways

PLoS ONE ◽

10.1371/journal.pone.0015945 ◽

2011 ◽

Vol 6 (1) ◽

pp. e15945 ◽

Cited By ~ 60

Author(s):

Jordan A. Krall ◽

Elsa M. Beyer ◽

Gavin MacBeath

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Signaling Pathways ◽

Growth Factor Receptor ◽

Receptor Ligand ◽

Ligand Interactions ◽

Epidermal Growth

Download Full-text

Migfilin Protein Promotes Migration and Invasion in Human Glioma through Epidermal Growth Factor Receptor-mediated Phospholipase C-γ and STAT3 Protein Signaling Pathways

Journal of Biological Chemistry ◽

10.1074/jbc.m112.393900 ◽

2012 ◽

Vol 287 (39) ◽

pp. 32394-32405 ◽

Cited By ~ 22

Author(s):

Yunwei Ou ◽

Ling Ma ◽

Lijia Dong ◽

Liying Ma ◽

Zitong Zhao ◽

...

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Signaling Pathways ◽

Phospholipase C ◽

Growth Factor Receptor ◽

Migration And Invasion ◽

Protein Signaling ◽

Human Glioma ◽

Epidermal Growth

Download Full-text

ebi regulates epidermal growth factor receptor signaling pathways in Drosophila

Genes & Development ◽

10.1101/gad.13.8.954 ◽

1999 ◽

Vol 13 (8) ◽

pp. 954-965 ◽

Cited By ~ 58

Author(s):

X. Dong ◽

L. Tsuda ◽

K. H. Zavitz ◽

M. Lin ◽

S. Li ◽

...

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Signaling Pathways ◽

Growth Factor Receptor ◽

Receptor Signaling ◽

Epidermal Growth ◽

Growth Factor Receptor Signaling

Download Full-text

Distinctive Epidermal Growth Factor Receptor/Extracellular Regulated Kinase-Independent and -Dependent Signaling Pathways in the Induction of Airway Mucin 5B and Mucin 5AC Expression by Phorbol 12-Myristate 13-Acetate

American Journal Of Pathology ◽

10.2353/ajpath.2007.060452 ◽

2007 ◽

Vol 170 (1) ◽

pp. 20-32 ◽

Cited By ~ 49

Author(s):

Daphne Yuan-chen Wu ◽

Reen Wu ◽

Sekhar P. Reddy ◽

Yong Chan Lee ◽

Mary Mann-Jong Chang

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Signaling Pathways ◽

Growth Factor Receptor ◽

Epidermal Growth ◽

Extracellular Regulated Kinase ◽

Airway Mucin

Download Full-text

Aucklandia lappa DC. extract enhances gefitinib efficacy in gefitinib-resistance secondary epidermal growth factor receptor mutations

Journal of Ethnopharmacology ◽

10.1016/j.jep.2017.06.011 ◽

2017 ◽

Vol 206 ◽

pp. 353-362

Author(s):

Guan Huang ◽

Yanli Tong ◽

Qidi He ◽

Jie Wang ◽

Zuanguang Chen

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Growth Factor Receptor ◽

Epidermal Growth ◽

Gefitinib Resistance

Download Full-text