Antitumor efficacy of CHMFL-KIT-110 solid dispersion in mouse xenograft models of human gastrointestinal stromal tumors

2021 ◽  
Author(s):  
Shengfu Wang ◽  
Chunyan Wang ◽  
Xiao Wang ◽  
Xiang Wang ◽  
Lina Huang ◽  
...  
Keyword(s):  
Solid Dispersion ◽  
Gastrointestinal Stromal Tumors ◽  
Antitumor Efficacy ◽  
Mouse Xenograft ◽  
Stromal Tumors ◽  
Xenograft Models

scholarly journals PD-1/PD-L1 Blockade Enhances T-cell Activity and Antitumor Efficacy of Imatinib in Gastrointestinal Stromal Tumors

2016 ◽  
Vol 23 (2) ◽  
pp. 454-465 ◽  
Author(s):  
Adrian M. Seifert ◽  
Shan Zeng ◽  
Jennifer Q. Zhang ◽  
Teresa S. Kim ◽  
Noah A. Cohen ◽  
...  
Keyword(s):  
T Cell ◽  
Gastrointestinal Stromal Tumors ◽  
Cell Activity ◽  
Antitumor Efficacy ◽  
Stromal Tumors

PLX9486 shows anti-tumor efficacy in patient-derived, tyrosine kinase inhibitor-resistant KIT-mutant xenograft models of gastrointestinal stromal tumors

2018 ◽  
Vol 19 (2) ◽  
pp. 201-210 ◽  
Author(s):  
Yemarshet K. Gebreyohannes ◽  
Elizabeth A. Burton ◽  
Agnieszka Wozniak ◽  
Bernice Matusow ◽  
Gaston Habets ◽  
...  
Keyword(s):  
Tyrosine Kinase ◽  
Tyrosine Kinase Inhibitor ◽  
Gastrointestinal Stromal Tumors ◽  
Kinase Inhibitor ◽  
Stromal Tumors ◽  
Xenograft Models

scholarly journals Antitumor Efficacy of the Anti-Interleukin-6 (IL-6) Antibody Siltuximab in Mouse Xenograft Models of Lung Cancer

2014 ◽  
Vol 9 (7) ◽  
pp. 974-982 ◽  
Author(s):  
Lanxi Song ◽  
Matthew A. Smith ◽  
Parul Doshi ◽  
Kate Sasser ◽  
William Fulp ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Interleukin 6 ◽  
Antitumor Efficacy ◽  
Mouse Xenograft ◽  
Xenograft Models

scholarly journals Macrophages and CD8+ T Cells Mediate the Antitumor Efficacy of Combined CD40 Ligation and Imatinib Therapy in Gastrointestinal Stromal Tumors

2018 ◽  
Vol 6 (4) ◽  
pp. 434-447 ◽  
Author(s):  
Jennifer Q. Zhang ◽  
Shan Zeng ◽  
Gerardo A. Vitiello ◽  
Adrian M. Seifert ◽  
Benjamin D. Medina ◽  
...  
Keyword(s):  
T Cells ◽  
Cd8 T Cells ◽  
Gastrointestinal Stromal Tumors ◽  
Imatinib Therapy ◽  
Antitumor Efficacy ◽  
Cd40 Ligation ◽  
Stromal Tumors

scholarly journals Plocabulin, a novel tubulin inhibitor, has potent antitumor activity in patient-derived xenograft models of gastrointestinal stromal tumors

2020 ◽  
Vol 13 (11) ◽  
pp. 100832
Author(s):  
Yannick Wang ◽  
Agnieszka Wozniak ◽  
Jasmien Wellens ◽  
Yemarshet K. Gebreyohannes ◽  
Maria Jose Guillén ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Gastrointestinal Stromal Tumors ◽  
Tubulin Inhibitor ◽  
Stromal Tumors ◽  
Patient Derived Xenograft ◽  
Xenograft Models

scholarly journals Robust Activity of Avapritinib, Potent and Highly Selective Inhibitor of Mutated KIT, in Patient-derived Xenograft Models of Gastrointestinal Stromal Tumors

2018 ◽  
Vol 25 (2) ◽  
pp. 609-618 ◽  
Author(s):  
Yemarshet K. Gebreyohannes ◽  
Agnieszka Wozniak ◽  
Madalina-Elena Zhai ◽  
Jasmien Wellens ◽  
Jasmien Cornillie ◽  
...  
Keyword(s):  
Gastrointestinal Stromal Tumors ◽  
Selective Inhibitor ◽  
Stromal Tumors ◽  
Patient Derived Xenograft ◽  
Xenograft Models
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