Chemomodulation of drugs involved in multidrug resistance in chronic lymphatic leukemia of the B-cell type

1994 ◽  
Vol 34 (4) ◽  
pp. 307-316 ◽  
Author(s):  
A. Reichle ◽  
H. Diddens ◽  
F. Altmayr ◽  
J. Rastetter ◽  
R. Andreesen
Keyword(s):  
Multidrug Resistance ◽  
B Cell ◽  
Chronic Lymphatic Leukemia ◽  
Cell Type ◽  
Lymphatic Leukemia

Chemomodulation of drugs involved in multidrug resistance in chronic lymphatic leukemia of the B-cell type

1994 ◽  
Vol 34 (4) ◽  
pp. 307-316 ◽  
Author(s):  
A. Reichle ◽  
H. Diddens ◽  
F. Altmayr ◽  
J. Rastetter ◽  
R. Andreesen
Keyword(s):  
Multidrug Resistance ◽  
B Cell ◽  
Chronic Lymphatic Leukemia ◽  
Cell Type ◽  
Lymphatic Leukemia

scholarly journals A real-time PCR assay for the quantification of residual malignant cells in B cell chronic lymphatic leukemia

Leukemia ◽  
2000 ◽  
Vol 14 (4) ◽  
pp. 754-766 ◽  
Author(s):  
T Pfitzner ◽  
A Engert ◽  
H Wittor ◽  
T Schinköthe ◽  
F Oberhäuser ◽  
...  
Keyword(s):  
B Cell ◽  
Real Time ◽  
Real Time Pcr ◽  
Malignant Cells ◽  
Chronic Lymphatic Leukemia ◽  
Pcr Assay ◽  
Lymphatic Leukemia

Chlorambucil Plus Theophylline vs Chlorambucil Alone as a Front Line Therapy for B-Cell Chronic Lymphatic Leukemia

2004 ◽  
Vol 45 (10) ◽  
pp. 2029-2035 ◽  
Author(s):  
Mohamed Mabed ◽  
Salah Aref ◽  
Manal Fouda ◽  
Solafa El-Sharawy
Keyword(s):  
B Cell ◽  
Chronic Lymphatic Leukemia ◽  
Front Line ◽  
Lymphatic Leukemia ◽  
Line Therapy

Normal B cell compartment in chronic lymphatic leukemia

2006 ◽  
Vol 8 (3) ◽  
pp. 121-124 ◽  
Author(s):  
A. Pluta ◽  
A. Górski ◽  
M. Nowaczyk ◽  
M. Modlińska
Keyword(s):  
B Cell ◽  
Chronic Lymphatic Leukemia ◽  
Cell Compartment ◽  
Lymphatic Leukemia

scholarly journals OCCURRENCE OF SURFACE IgM, IgD, AND FREE LIGHT CHAINS ON HUMAN LYMPHOCYTES

1974 ◽  
Vol 139 (2) ◽  
pp. 451-456 ◽  
Author(s):  
Shu Man Fu ◽  
Robert J. Winchester ◽  
Henry G. Kunkel
Keyword(s):  
B Cell ◽  
Human Lymphocytes ◽  
Light Chains ◽  
Surface Markers ◽  
Chronic Lymphatic Leukemia ◽  
Simultaneous Presence ◽  
Free Light Chains ◽  
Single Class ◽  
Previous Evidence ◽  
Lymphatic Leukemia

An analysis was made of the immunoglobulin surface markers of the cells of patients with chronic lymphatic leukemia (CLL) in view of previous evidence of their monoclonal B-cell character. The simultaneous presence of IgM and IgD on the surface of the majority of lymphocytes was demonstrated by both immunofluorescence and hemagglutination inhibition in most cases. However, cases were observed with surface IgM without IgD as well as cases with IgD without IgM. IgG and IgA were absent. Studies of the light chains indicated only a single class in a given case. In addition to bound light chains, free light chains were readily demonstrated in most cases through the use of antisera specific for "free chain" determinants. It thus appeared that there are three major types of surface Ig on CLL lymphocytes, IgM, IgD, and free light chains.

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