Kawasaki disease and Henoch Schonlein purpura: changing trends at a tertiary care hospital in north India (1993–2008)

Background: This study examines the clinical and laboratory features of children with Henoch-Schönlein purpura.Methods: A retrospective study was applied for the 32 Henoch-Schönlein purpura patients who were monitored between January 2014 and June 2017 at the Pediatric clinic of a tertiary care hospital. The diagnoses were made based on the HSP criteria of the American College of Rheumatology. Age, gender, clinical and laboratory findings of the patients were recorded.Results: The mean age of the 32 Henoch-Schönlein purpura patients was 9.29±3.29 years. Complaints at the time of admission were as follows: 93.8% of the patients (n=30) had rash; 40.6% (n=13) had abdominal pain; and 59.4% (n=19) had joint involvement and inability to walk. The results of fecal occult blood test examined during the admission were found as negative for the 75% (n=25) of patients and positive for the 19% (n=6) of patients. According to the urinary specimens, which were considered as the evidence of renal involvement at the applications, proteinuria was found negative for the 27 (8.4%) patients and positive for the 5 (1.6%) patients; hematuria was negative for the 29 (90.6%) children and positive for the 3 (%9.4) children. Antihistamine and non-steroidal anti-inflammatory were started as the treatment to the patients. During the follow-up, the 15.5% of patients had positive fecal blood tests although their test results were negative at the admission. During the clinical follow-up, the presence of proteinuria was found positive for the 6.3% of patients who had negative proteinuria test at their admissions.Conclusions: Henoch-Schönlein purpura is a childhood vasculitis that manifests itself with rash and joint findings. It can cause significant complications due to gastrointestinal and genitourinary system involvement.

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365 Profile of henoch schonlein purpura (hsp) nephritis: 23 years experience at a tertiary care centre in north india

10.1136/lupus-2017-000215.365 ◽

2017 ◽

Author(s):

A Gupta ◽

A Kumar ◽

A Gupta ◽

R Nada ◽

RW Minz ◽

...

Keyword(s):

Tertiary Care ◽

North India ◽

Care Centre ◽

Henoch Schonlein Purpura ◽

Tertiary Care Centre ◽

Schonlein Purpura ◽

Henoch Schönlein Purpura

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Clinical profile and outcome of Henoch Schonlein purpura in a tertiary care hospital in South India

International Journal of Contemporary Pediatrics ◽

10.18203/2349-3291.ijcp20171493 ◽

2017 ◽

Vol 4 (3) ◽

pp. 822 ◽

Cited By ~ 1

Author(s):

Shanavas Abbas ◽

Geetha S. ◽

Deepthi R.V. ◽

Jubin Kamar ◽

Susan Uthup

Keyword(s):

Clinical Features ◽

Renal Involvement ◽

Tertiary Care ◽

Clinical Profile ◽

Treatment Modalities ◽

Joint Involvement ◽

Care Hospital ◽

Henoch Schonlein Purpura ◽

Schonlein Purpura ◽

Henoch Schönlein Purpura

Background: Henoch Schonlein purpura (HSP) is the most common systemic vasculitis in children. It is an immunoglobulin A (IgA) mediated systemic small-vessel vasculitis, with IgA deposition in vessel walls leading to symptoms involving the skin, joints, intestines, and kidneys. The objective of present study was to identify and describe the clinical profile, pattern of joint involvement, histopathological features, treatment modalities and complications of Henoch Schonlein purpura.Methods: 52 children less than 12 years diagnosed to have Henoch Schonlein Purpura according to the European League against Rheumatism criteria were included in the study. All patients were subjected to detailed history taking and thorough examination. The clinical features, investigations, management and complications of the disease were studied. Descriptive statistics was used to analyse the results.Results: The common clinical features were palpable purpura (100%) followed by arthritis (66%) and abdominal pain (50%). Renal manifestations were in the form of hematuria in 12% of the patients. Skin biopsy was done in 25 patients of which 19 had findings suggestive of Henoch Schonlein purpura. Steroids were used in 42% of patients. The severity of illness was associated with lower mean age, arthritis, leg edema and stool occult blood.Conclusions: The clinical features of Henoch Schonlein purpura in the population were different from the previously published studies. Renal involvement was less common. The short-term outcome of the patients were satisfactory.

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