Quantitative CT analysis of pulmonary ground-glass opacity nodules for distinguishing invasive adenocarcinoma from non-invasive or minimally invasive adenocarcinoma: the added value of using iodine mapping

2015 ◽  
Vol 26 (1) ◽  
pp. 43-54 ◽  
Author(s):  
Ji Ye Son ◽  
Ho Yun Lee ◽  
Jae-Hun Kim ◽  
Joungho Han ◽  
Ji Yun Jeong ◽  
...  
2018 ◽  
Vol 27 (1) ◽  
pp. 45-48
Author(s):  
Shinsuke Uchida ◽  
Koji Tsuta ◽  
Masahiko Kusumoto ◽  
Kouya Shiraishi ◽  
Takashi Kohno ◽  
...  

Pulmonary collision tumors have been described as a special entity of synchronous multiple lung cancer. There have been no reports detailing the chronological changes in primary collision lung cancers on chest computed tomography. We report a case of ground-glass lung nodules gradually colliding with each other. The collision tumors of the lung were composed of minimally invasive adenocarcinoma and adenocarcinoma in situ with epidermal growth factor mutations. Immunohistochemically, the Ki-67 labeling indices were different in the 2 components. Ki-67 staining was useful to distinguish the 2 components. The 2 dominant ground-glass tumors grew slowly with radiologic and pathologic heterogeneity.


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