Effects of trehalose on recurrence of remodeling after ventricular reconstruction in rats with ischemic cardiomyopathy

2022 ◽  
Author(s):  
Tetsuya Hieda ◽  
Yasushige Shingu ◽  
Satoshi Sugimoto ◽  
Hidetsugu Asai ◽  
Tomoji Yamakawa ◽  
...  
Keyword(s):  
Ischemic Cardiomyopathy ◽  
Ventricular Reconstruction

Broad potential applicability for surgical ventricular reconstruction in the treatment of ischemic cardiomyopathy and heart failure

2003 ◽  
Vol 9 (5) ◽  
pp. S51
Author(s):  
Catherine C. Fallick ◽  
Colleen M. Healey ◽  
Steven W. Boyce ◽  
Mercedes K.C. Dullum ◽  
John S. Golden
Keyword(s):  
Heart Failure ◽  
Ischemic Cardiomyopathy ◽  
Surgical Ventricular Reconstruction ◽  
Potential Applicability ◽  
Ventricular Reconstruction

scholarly journals The impact of left ventricular reconstruction on survival in patients with ischemic cardiomyopathy

2006 ◽  
Vol 30 (5) ◽  
pp. 753-759 ◽  
Author(s):  
J ONEILL ◽  
R STARLING ◽  
P MCCARTHY ◽  
N ALBERT ◽  
B LYTLE ◽  
...  
Keyword(s):  
Ischemic Cardiomyopathy ◽  
Left Ventricular ◽  
Left Ventricular Reconstruction ◽  
Ventricular Reconstruction ◽  
The Impact

Results of reconstructive interventions in patients with ischemic cardiomyopathy

2020 ◽  
pp. 021849232098346
Author(s):  
Vladimir M Shipulin ◽  
Andrey S Pryakhin ◽  
Sergey L Andreev ◽  
Vladimir V Shipulin ◽  
Boris N Kozlov
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass Grafting ◽  
Coronary Artery Bypass ◽  
Ischemic Cardiomyopathy ◽  
Artery Bypass ◽  
Left Ventricular ◽  
Bypass Grafting ◽  
Left Ventricular Reconstruction ◽  
Ventricular Reconstruction

Background Effective treatment of patients with ischemic cardiomyopathy is one of the most difficult issues in contemporary cardiac surgery. The aim of this study was to evaluate the long-term effectiveness of reconstructive interventions on the left ventricle during chronic heart failure in patients with ischemic cardiomyopathy. Methods Between March 2013 and December 2017, 178 patients underwent surgical treatment for ischemic cardiomyopathy. Isolated coronary artery bypass grafting was compared with coronary artery bypass grafting with left ventricular reconstruction, using propensity score matching analysis. The primary endpoints of the study were hospital mortality and long-term survival. Results After propensity score matching, 29 pairs of patients were compared. The 30-day hospital mortality was comparable (6.8% versus 6.8%, p = 0.952), the average follow-up was 37.4 ± 12.6 months, with no statistically significant difference in mortality from all causes ( p = 0.352). After coronary artery bypass in combination with left ventricular reconstruction, patients showed a statistically significant decrease in clinical and functional indicators of chronic heart failure compared to those who had coronary artery bypass grafting alone, in terms of peak oxygen consumption (15.3 versus 13.5 mL·kg−1·min−1, p = 0.043) and N-terminal pro-brain natriuretic peptide concentrations (298.6 versus 461.1 pg·mL−1, p = 0.032). Conclusions Compared to isolated coronary artery bypass, coronary artery bypass in combination with left ventricular reconstruction for the treatment of ischemic cardiomyopathy leads to a significant decrease in the clinical and functional parameters of chronic heart failure in the long-term postoperative period.

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