Neonatal gastric perforations in very low birth weight infants: a single center experience and review of the literature

Introduction We present a single-center experience with very low birth weight (VLBW) infants with focal intestinal perforation (FIP), comparing the results of primary anastomosis (PA) and stoma opening (SO). Materials and Methods Clinical records of VLBW infants with FIP who underwent surgery between 2006 and 2015 were reviewed. Patients were divided into two groups according to the procedure performed: limited bowel resection and PA or SO. Patients with gastric perforation or patients who underwent clip and drop were excluded. Information regarding birth weight (BW), gestational age (GA), weight at surgery (WS), number of abdominal reoperations, duration of parenteral nutrition (PN), and demise was recorded. Results In this study, 40 patients were included: 22 in PA group and 18 in SO group. BW was 865 g in PA and 778 in SO (p-value: 0.2). GA was 26.1 weeks in PA and 25.6 in SO (p-value: 0.3). WS was 1,014 g in PA and 842 in SO (p-value: 0.09). Duration of surgery was 115 minutes in PA and 122 in SO (p-value: 0.67). Five patients (23%) belonging to PA group developed complications and required SO. Five patients (23%) demised in PA group and six (33%) in SO (p-value: 0.2). Seventeen abdominal reoperations were performed in PA group and 22 in SO group (p-value: 0.08). Conclusion Both procedures appear to be safe. When possible, PA should be performed as it reduces the number of abdominal reinterventions.

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Delayed diagnosis of spontaneous intestinal perforation among very low birth weight neonates: A single center experience

Journal of Perinatology ◽

10.1038/s41372-019-0480-0 ◽

2019 ◽

Vol 39 (11) ◽

pp. 1509-1520

Author(s):

Doron J. Kahn ◽

Sandra Gregorisch ◽

Jill S. Whitehouse ◽

Paul D. Fisher

Keyword(s):

Birth Weight ◽

Low Birth Weight ◽

Intestinal Perforation ◽

Very Low Birth Weight ◽

Delayed Diagnosis ◽

Single Center ◽

Single Center Experience ◽

Spontaneous Intestinal Perforation

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Pre-discharge growth pattern of very low birth weight infants (VLBW): A 5 year single center experience

Journal of Neonatal-Perinatal Medicine ◽

10.3233/npm-200592 ◽

2020 ◽

pp. 1-6

Author(s):

S.H. Elbeely ◽

M.A. AlQurashi

Keyword(s):

Birth Weight ◽

Low Birth Weight ◽

Gestational Age ◽

Growth Pattern ◽

Very Low Birth Weight ◽

Single Center ◽

Low Birth Weight Infants ◽

Cross Sectional ◽

Vlbw Infants ◽

The Mean

BACKGROUND: Very low birth weight infants born prematurely are at greater risk for growth delays that lead to Ex-utero Growth Restriction (EUGR) during vulnerable periods of organ structural and functional development. There is considerable evidence that early growth failure has adverse effects on long term neurodevelopment in children which often persists into adulthood. METHODS: This is a single-center cross-sectional study on live newborn infants with birth weight ranges from 500 to 1500 grams (VLBW) and gestational age (GA) between 24–32 weeks who were admitted to NICU at KAMC-Jeddah over a 5 year period (2009–2013). This study aims to evaluate predischarge growth pattern of VLBW infants in terms of weight, head circumference (HC) and length and to identify important variables that have influenced such growth pattern. RESULTS: Of the 135 infants included in the final analysis, 68 (50.4%) were male and 67 (49.6%) were female and the mean gestational age was 28.83±2.064 weeks and the mean birth weight 1166.74±256 grams. Ninety-two infants (68%) had discharge weight at ≤10th percentile and forty four (32%) had their weight >10th percentile. HC was the lowest affected among the anthropometric measurements with 42% ≤10th percentile. In terms of linear growth, 62% had their length ≤10th percentile. Amongst infants born ≤750 grams, 71% and 70% had HC and height at ≤10th percentile respectively, at the time of discharge. BPD was significantly associated with EUGR (p = 0.026). CONCLUSIONS: This study demonstrates that almost 2/3rd of VLBW infants born at KAMC-Jeddah with birth weight ≤750 grams were discharged home with EUGR as demonstrated by their weight, length, and HC ≤10th percentile. BPD was found to be significantly associated with EUGR amongst post-natal factors influencing EUGR.

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