scholarly journals Views of nursing staff on computerized dementia screening

2019 ◽  
Vol 52 (S4) ◽  
pp. 258-263 ◽  
Author(s):  
Stelios Zygouris ◽  
Mara Gkioka ◽  
Despoina Moraitou ◽  
Birgit Teichmann ◽  
Thrasyvoulos Tsiatsos ◽  
...  

Abstract Background Cognitive disorders such as dementia are common among older adults admitted to general hospitals. They can complicate treatment leading to longer hospitalization and worse outcomes. They often remain underdiagnosed as the busy routine of the hospital does not enable efficient screening and available screening instruments are not suitable for the hospital environment. Computerized cognitive testing (CCT) has been proposed as an efficient screening method as it can be employed by nonspecialists, such as nurses while featuring automatic scoring and interpretation of results. Objective This study validated a newly developed questionnaire for measuring the attitudes of Greek nurses towards computerized dementia screening. Material and methods The questionnaire was validated in a sample of 212 undergraduate psychology students and subsequently administered to a sample of 19 nurses working in a general hospital. Reliability of the questionnaire was calculated using Cronbach’s alpha (= 0.762). Factor analysis revealed the existence of a single factor (acceptability-feasibility) that accounted for 33.73% of variance with an eigenvalue of 3.036. Results The total score of all the items loading on the single factor (acceptability-feasibility) was calculated. Scores ranged between 10 and 40 with the average score for the validation group being 29.33 (SD = 4.89) and the average score for the nurses’ group being 29.50 (SD = 3.20). Discussion The questionnaire has acceptable reliability. Results indicate that acceptability-feasibility is high in both groups and there were no statistically significant differences between the two groups.

2017 ◽  
Vol 27 (8) ◽  
pp. 1441-1448 ◽  
Author(s):  
Sachithra Amarin Hettiarachchi ◽  
Su-Jin Lee ◽  
Youngdeuk Lee ◽  
Young-Kyung Kwon ◽  
Mahanama De Zoysa ◽  
...  

RSC Advances ◽  
2020 ◽  
Vol 10 (70) ◽  
pp. 42804-42809
Author(s):  
Xuelian Liu ◽  
Dongyan Yang ◽  
Fahong Yin ◽  
Jia-Qi Li ◽  
Yumei Xiao ◽  
...  

In this study, the “plug-in molecular” method was firstly used to screen new strobilurin fungicides. The results indicated this is a highly efficient screening method for active compounds with guiding significance for the synthesis of new pesticides.


2015 ◽  
Vol 54 (3) ◽  
pp. 154-160
Author(s):  
Csaba Móczár ◽  
Imre Rurik

Abstract Introduction. Besides participation in the primary prevention, screening as secondary prevention is an important requirement for primary care services. The effect of this work is influenced by the characteristics of individual primary care practices and doctors’ screening habits, as well as by the regulation of screening processes and available financial resources. Between 1999 and 2009, a managed care program was introduced and carried out in Hungary, financed by the government. This financial support and motivation gave the opportunity to increase the number of screenings. Method. 4,462 patients of 40 primary care practices were screened on the basis of SCORE risk assessment. The results of the screening were compared on the basis of two groups of patients, namely: those who had been pre-screened (pre-screening method) for known risk factors in their medical history (smoking, BMI, age, family cardiovascular history), and those randomly screened. The authors also compared the mortality data of participating primary care practices with the regional and national data. Results. The average score was significantly higher in the pre-screened group of patients, regardless of whether the risk factors were considered one by one or in combination. Mortality was significantly lower in the participating primary practices than had been expected on the basis of the national mortality data. Conclusion. This government-financed program was a big step forward to establish a proper screening method within Hungarian primary care. Performing cardiovascular screening of a selected target group is presumably more appropriate than screening within a randomly selected population. Both methods resulted in a visible improvement in regional mortality data, though it is very likely that with pre-screening a more cost-effective selection for screening may be obtained.


1993 ◽  
Vol 57 (10) ◽  
pp. 1747-1749 ◽  
Author(s):  
Naoharu Watanabe ◽  
Akihiko Watanabe ◽  
Chikashi Ogura ◽  
Hideo Etoh ◽  
Kanzo Sakata ◽  
...  

2004 ◽  
Vol 60 (1) ◽  
pp. 5-10 ◽  
Author(s):  
Barbara Wusk ◽  
G. A. Kullak-Ublick ◽  
C. Rammert ◽  
A. von Eckardstein ◽  
M. Fried ◽  
...  

1990 ◽  
Vol 73 (11) ◽  
pp. 81-89 ◽  
Author(s):  
Kiyohiro Furutani ◽  
Makoto Suwa ◽  
Kazutami Arimoto ◽  
Koichiro Mashiko ◽  
Michihiro Yamada ◽  
...  

2020 ◽  
Author(s):  
Xiaojian Han ◽  
Yingming Wang ◽  
Shenglong Li ◽  
Chao Hu ◽  
Tingting Li ◽  
...  

Abstract After the epidemic of COVID-19, neutralizing antibodies (NAbs) against SARS-CoV-2 has been developed for the preventative and therapeutic purposes. However, few methodologies are reported in detail on how to rapidly and efficiently generate NAbs of interest. Here, we present a strategically optimized screening method for NAbs, which has enabled us to obtain SARS-CoV-2 receptor-binding domain (RBD) specific monoclonal Abs within 4 days, followed by additional 2 days to evaluate their neutralizing activities. Using this method, we obtained 198 specific Abs against SARS-CoV-2 RBD from the blood samples of COVID-19 convalescent patients, and 96 of them showed neutralizing activity. At least 20% of these NAbs exhibited high neutralizing potency. The top 2 NAbs showed the half-maximal inhibitory concentration (IC50) to block authentic SARS-CoV-2 at 9.88 and 11.13 ng/ml, respectively. Altogether, our study provides a fundamental methodology for discovering NAbs with potential preventative and therapeutic value for emerging infectious diseases.


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