scholarly journals The application of “plug-in molecules” method in novel strobilurin fungicides screening

RSC Advances ◽  
2020 ◽  
Vol 10 (70) ◽  
pp. 42804-42809
Author(s):  
Xuelian Liu ◽  
Dongyan Yang ◽  
Fahong Yin ◽  
Jia-Qi Li ◽  
Yumei Xiao ◽  
...  
Keyword(s):  
Screening Method ◽  
Molecular Method ◽  
Active Compounds ◽  
Highly Efficient ◽  
Strobilurin Fungicides ◽  
Efficient Screening

In this study, the “plug-in molecular” method was firstly used to screen new strobilurin fungicides. The results indicated this is a highly efficient screening method for active compounds with guiding significance for the synthesis of new pesticides.

Nickel(0)-Catalyzed Linear-Selective Hydroarylation of Unactivated Alkenes and Styrenes with Arylboron Acids

2018 ◽  
Author(s):  
Honggui Lv ◽  
Li-Jun Xiao ◽  
Dongbing Zhao ◽  
Qi-Lin Zhou
Keyword(s):  
Butyric Acid ◽  
Biologically Active Compounds ◽  
Biologically Active ◽  
Active Compounds ◽  
Highly Efficient ◽  
Organoboronic Acids

Herein, we realized the first linear-selective hydroarylation of unactivated alkenes and styrenes with organoboronic acids by introducing directing groupon alkenes. Our method is highly efficient and scalable, and provides a modular route to assemble structurally diverse alkylarenes, especially for γ-aryl butyric acid derivatives, which have been widely utilized as chemical feedstocks to access multiple marketed drugs, and biologically active compounds.<br>

A Rapid and Efficient Screening Method for Antibacterial Compound-Producing Bacteria

2017 ◽  
Vol 27 (8) ◽  
pp. 1441-1448 ◽  
Author(s):  
Sachithra Amarin Hettiarachchi ◽  
Su-Jin Lee ◽  
Youngdeuk Lee ◽  
Young-Kyung Kwon ◽  
Mahanama De Zoysa ◽  
...  
Keyword(s):  
Screening Method ◽  
Antibacterial Compound ◽  
Efficient Screening

scholarly journals Views of nursing staff on computerized dementia screening

2019 ◽  
Vol 52 (S4) ◽  
pp. 258-263 ◽  
Author(s):  
Stelios Zygouris ◽  
Mara Gkioka ◽  
Despoina Moraitou ◽  
Birgit Teichmann ◽  
Thrasyvoulos Tsiatsos ◽  
...  
Keyword(s):  
Screening Method ◽  
Cognitive Disorders ◽  
Cognitive Testing ◽  
Hospital Environment ◽  
Average Score ◽  
Single Factor ◽  
Dementia Screening ◽  
Automatic Scoring ◽  
Efficient Screening ◽  
Acceptable Reliability

Abstract Background Cognitive disorders such as dementia are common among older adults admitted to general hospitals. They can complicate treatment leading to longer hospitalization and worse outcomes. They often remain underdiagnosed as the busy routine of the hospital does not enable efficient screening and available screening instruments are not suitable for the hospital environment. Computerized cognitive testing (CCT) has been proposed as an efficient screening method as it can be employed by nonspecialists, such as nurses while featuring automatic scoring and interpretation of results. Objective This study validated a newly developed questionnaire for measuring the attitudes of Greek nurses towards computerized dementia screening. Material and methods The questionnaire was validated in a sample of 212 undergraduate psychology students and subsequently administered to a sample of 19 nurses working in a general hospital. Reliability of the questionnaire was calculated using Cronbach’s alpha (= 0.762). Factor analysis revealed the existence of a single factor (acceptability-feasibility) that accounted for 33.73% of variance with an eigenvalue of 3.036. Results The total score of all the items loading on the single factor (acceptability-feasibility) was calculated. Scores ranged between 10 and 40 with the average score for the validation group being 29.33 (SD = 4.89) and the average score for the nurses’ group being 29.50 (SD = 3.20). Discussion The questionnaire has acceptable reliability. Results indicate that acceptability-feasibility is high in both groups and there were no statistically significant differences between the two groups.

Efficient Screening Method for Antifouling Substances

1993 ◽  
Vol 57 (10) ◽  
pp. 1747-1749 ◽  
Author(s):  
Naoharu Watanabe ◽  
Akihiko Watanabe ◽  
Chikashi Ogura ◽  
Hideo Etoh ◽  
Kanzo Sakata ◽  
...  
Keyword(s):  
Screening Method ◽  
Efficient Screening

scholarly journals A Human TREK-1/HEK Cell Line: A Highly Efficient Screening Tool for Drug Development in Neurological Diseases

PLoS ONE ◽  
2011 ◽  
Vol 6 (10) ◽  
pp. e25602 ◽  
Author(s):  
Hamid Moha ou Maati ◽  
Rémi Peyronnet ◽  
Christelle Devader ◽  
Julie Veyssiere ◽  
Fabien Labbal ◽  
...  
Keyword(s):  
Drug Development ◽  
Cell Line ◽  
Screening Tool ◽  
Neurological Diseases ◽  
Highly Efficient ◽  
Efficient Screening

scholarly journals Thiopurine S-methyltransferase polymorphisms: efficient screening method for patients considering taking thiopurine drugs

2004 ◽  
Vol 60 (1) ◽  
pp. 5-10 ◽  
Author(s):  
Barbara Wusk ◽  
G. A. Kullak-Ublick ◽  
C. Rammert ◽  
A. von Eckardstein ◽  
M. Fried ◽  
...  
Keyword(s):  
Screening Method ◽  
Efficient Screening
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