Dietary antioxidant capacity is associated with improved serum antioxidant status and decreased serum C-reactive protein and plasma homocysteine concentrations

2013 ◽  
Vol 52 (8) ◽  
pp. 1901-1911 ◽  
Author(s):  
Meng Yang ◽  
Sang-Jin Chung ◽  
Anna Floegel ◽  
Won O. Song ◽  
Sung I. Koo ◽  
...  
Circulation ◽  
2001 ◽  
Vol 103 (23) ◽  
pp. 2788-2791 ◽  
Author(s):  
Simonetta Friso ◽  
Paul F. Jacques ◽  
Peter W.F. Wilson ◽  
Irwin H. Rosenberg ◽  
Jacob Selhub

Redox Report ◽  
2016 ◽  
Vol 21 (2) ◽  
pp. 67-74 ◽  
Author(s):  
Marcos Garcia-Lacarte ◽  
Fermin I. Milagro ◽  
Maria A. Zulet ◽  
J. Alfredo Martinez ◽  
Maria L. Mansego

Toxicology ◽  
2019 ◽  
Vol 411 ◽  
pp. 43-48 ◽  
Author(s):  
Alessandro Attanzio ◽  
Anna Frazzitta ◽  
Sonya Vasto ◽  
Luisa Tesoriere ◽  
Anna Maria Pintaudi ◽  
...  

2017 ◽  
Vol 6 (1) ◽  
pp. 47 ◽  
Author(s):  
Mahdiyeh Sheikhi ◽  
Elham Sharifi-Zahabi ◽  
Zamzam Paknahad

2020 ◽  
Vol 2020 ◽  
pp. 1-7 ◽  
Author(s):  
Nour Elkhair Ali ◽  
Lamis AbdelGadir Kaddam ◽  
Suad Yousif Alkarib ◽  
Babikir Gabir Kaballo ◽  
Sami Ahmed Khalid ◽  
...  

Background. Oxidative processes might increase in patients with end-stage renal disease (ESRD) according to the current literature. Oxidative stress (OS) is a risk factor of atherosclerosis and cardiovascular complications, which are major causes of mortality among ESRD patients. Haemodialysis (HD) is life-saving procedure, nevertheless it is an active chronic inflammatory status that could augment cardiovascular disease and increase mortality. Gum Arabic (GA) has been claimed to act as an antioxidant and anti-inflammatory agent in experimental studies and clinical trials. Therefore, we assumed GA supplementation among haemodialysis patients would reduce oxidative stress and consequently reduce the state of chronic inflammatory activation associated with haemodialysis. Methods. Forty end-stage renal failure (ESRF) patients aged 18–80 years who were on regular haemodialysis in Arif Renal Center, Omdurman, Sudan, were recruited. All recruited patients met the inclusion criteria and signed informed consent prior to enrolment. The patients received 30 g/day of GA for 12 weeks. C-reactive protein (CRP) and complete blood count (CBC) were measured as baseline and monthly. Total antioxidant capacity (TAC) and oxidative stress marker malondialdehyde (MDA) levels were measured before and after GA intake. Ethical approval from the National Medicines and Poisons Board was obtained. Results. Gum Arabic significantly augmented total antioxidant capacity level (P<0.001) (95% CI, 0.408–0.625) and also attenuated oxidative marker MDA and C-reactive protein (P<0.001). Conclusions. GA has revealed potent antioxidative and anti-inflammatory properties in haemodialysis patients. Oral digestion of GA (30 g/day) decreased oxidative stress and inflammatory markers among haemodialysis patients. Trial registration. ClinicalTrials.gov Identifier: NCT03214692, registered 11 July 2017 (prospective registration).


Antioxidants ◽  
2020 ◽  
Vol 9 (8) ◽  
pp. 728
Author(s):  
Niels van der Schaft ◽  
Katerina Trajanoska ◽  
Fernando Rivadeneira ◽  
M. Arfan Ikram ◽  
Josje D. Schoufour ◽  
...  

Although there is some evidence that total dietary antioxidant capacity (TDAC) is inversely associated with the presence of obesity, no longitudinal studies have been performed investigating the effect of TDAC on comprehensive measures of body composition over time. In this study, we included 4595 middle-aged and elderly participants from the Rotterdam Study, a population-based cohort. We estimated TDAC among these individuals by calculating a ferric reducing ability of plasma (FRAP) score based on data from food-frequency questionnaires. Body composition was assessed by means of dual X-ray absorptiometry at baseline and every subsequent 3–5 years. From these data, we calculated fat mass index (FMI), fat-free mass index (FFMI), android-to-gynoid fat ratio (AGR), body fat percentage (BF%) and body mass index (BMI). We also assessed hand grip strength at two time points and prevalence of sarcopenia at one time point in a subset of participants. Data were analyzed using linear mixed models or multinomial logistic regression models with multivariable adjustment. We found that higher FRAP score was associated with higher FFMI (0.091 kg/m2 per standard deviation (SD) higher FRAP score, 95% CI 0.031; 0.150), lower AGR (−0.028, 95% CI −0.053; −0.003), higher BMI (0.115, 95% CI 0.020; 0.209) and lower BF% (−0.223, 95% CI −0.383; −0.064) across follow-up after multivariable adjustment. FRAP score was not associated with hand grip strength or sarcopenia. Additional adjustment for adherence to dietary guidelines and exclusion of individuals with comorbid disease at baseline did not change our results. In conclusion, dietary intake of antioxidants may positively affect the amount of lean mass and overall body composition among the middle-aged and elderly.


2002 ◽  
Vol 39 ◽  
pp. 359
Author(s):  
Margaret Leila Rasouli ◽  
Matthew J. Budoff ◽  
Robert Park ◽  
Douglas Aziz

Circulation ◽  
2000 ◽  
Vol 102 (11) ◽  
pp. 1227-1232 ◽  
Author(s):  
Jeffrey L. Anderson ◽  
Joseph B. Muhlestein ◽  
Benjamin D. Horne ◽  
John F. Carlquist ◽  
Tami L. Bair ◽  
...  

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