scholarly journals Impact of dietary supplementation with resistant dextrin (NUTRIOSE®) on satiety, glycaemia, and related endpoints, in healthy adults

2021 ◽  
Author(s):  
Mark R. Hobden ◽  
Daniel M. Commane ◽  
Laetitia Guérin-Deremaux ◽  
Daniel Wils ◽  
Clementine Thabuis ◽  
...  
Keyword(s):  
Body Weight ◽  
Treatment Period ◽  
Weight Control ◽  
Day Treatment ◽  
Normal Weight ◽  
Healthy Adults ◽  
Lower Systolic Blood Pressure ◽  
Metabolic Markers ◽  
Body Weight Control ◽  
Resistant Dextrin

Abstract Purpose Resistant dextrin (RD) supplementation has been shown to alter satiety, glycaemia, and body weight, in overweight Chinese men; however, there are limited data on its effects in other demographic groups. Here, we investigated the effects of RD on satiety in healthy adults living in the United Kingdom. Methods 20 normal weight and 16 overweight adults completed this randomised controlled cross-over study. Either RD (14 g/day NUTRIOSE® FB06) or maltodextrin control was consumed in mid-morning and mid-afternoon preload beverages over a 28-day treatment period with crossover after a 28-day washout. During 10-h study visits (on days 1, 14, and 28 of each treatment period), satietogenic, glycaemic and anorectic hormonal responses to provided meals were assessed. Results Chronic supplementation with RD was associated with higher fasted satiety scores at day 14 (P = 0.006) and day 28 (P = 0.040), compared to control. RD also increased satiety after the mid-morning intervention drink, but it was associated with a reduction in post-meal satiety following both the lunch and evening meals (P < 0.01). The glycaemic response to the mid-morning intervention drink (0–30 min) was attenuated following RD supplementation (P < 0.01). Whilst not a primary endpoint we also observed lower systolic blood pressure at day 14 (P = 0.035) and 28 (P = 0.030), compared to day 1, following RD supplementation in the normal weight group. Energy intake and anthropometrics were unaffected. Conclusions RD supplementation modified satiety and glycaemic responses in this cohort, further studies are required to determine longer-term effects on body weight control and metabolic markers. Clinicaltrials.gov registration CT02041975 (22/01/2014)

Anorexia Nervosa at Normal Body Weight!–The Abnormal Normal Weight Control Syndrome

1982 ◽  
Vol 11 (3) ◽  
pp. 203-233 ◽  
Author(s):  
A. H. Crisp
Keyword(s):  
Body Weight ◽  
Anorexia Nervosa ◽  
Weight Control ◽  
Eating Behaviour ◽  
Normal Weight ◽  
Normal Body ◽  
Self Mutilation ◽  
Normal Body Weight ◽  
Body Weight Control ◽  
Normal Weight Control

Disgust with ‘fatness' and a consequent preoccupation with body weight, coupled with an inability to reduce it to or sustain it at the desired low level, characterizes the abnormal normal weight control syndrome. Individuals remain sexually active in a biological sense and often also socially. Indeed their sexual behaviour may be as impulse ridden as is their eating behaviour, which often comprises phases of massive bingeing coupled with vomiting and/or purgation. The syndrome is unlike frank anorexia nervosa in that the latter involves a regression to a position of phobic avoidance of normal body weight and consequent low body weight control with inhibition of both biological and social sexual activity. In abnormal normal weight control there is a strong and sometimes desperate hedonistic and extrovert element that will often not be denied so long as body weight does not get too low. Individuals nevertheless feel desperately ‘out of control’ and insecure beneath their bravura. The syndrome is much more common in females than in males. There is a clinical overlap with anorexia nervosa and obesity in many cases as the disorder evolves. Depression, stealing, drug dependence (including alcohol) and acute self-poisoning and self-mutilation are common complications. Clinic cases probably only represent the tip of the iceberg of a much more widespread morbidity within the general population. Like anorexia nervosa and for the same reasons the disorder is probably more common than it used to be.

Recent insights into body weight control: From physiology to pathology

2001 ◽  
Vol 7 (11) ◽  
pp. 571-578 ◽  
Author(s):  
Robert Krysiak ◽  
Bogus?aw Okopie? ◽  
Dariusz Belowski ◽  
Andrzej Madej ◽  
Zbigniew Stanis?aw Herman
Keyword(s):  
Body Weight ◽  
Weight Control ◽  
Body Weight Control

scholarly journals Relationship between Prenatal or Postnatal Exposure to Pesticides and Obesity: A Systematic Review

2021 ◽  
Vol 18 (13) ◽  
pp. 7170
Author(s):  
Helena Pinos ◽  
Beatriz Carrillo ◽  
Ana Merchán ◽  
Judit Biosca-Brull ◽  
Cristian Pérez-Fernández ◽  
...  
Keyword(s):  
Systematic Review ◽  
Body Weight ◽  
Weight Control ◽  
Animal Studies ◽  
Pesticide Exposure ◽  
Endocrine Disrupting Chemicals ◽  
Overweight And Obesity ◽  
Postnatal Exposure ◽  
Body Weight Control ◽  
The Impact

In recent years, the worldwide prevalence of overweight and obesity among adults and children has dramatically increased. The conventional model regarding the onset of obesity is based on an imbalance between energy intake and expenditure. However, other possible environmental factors involved, such as the exposure to chemicals like pesticides, cannot be discarded. These compounds could act as endocrine-disrupting chemicals (EDC) that may interfere with hormone activity related to several mechanisms involved in body weight control. The main objective of this study was to systematically review the data provided in the scientific literature for a possible association between prenatal and postnatal exposure to pesticides and obesity in offspring. A total of 25 human and 9 animal studies were analyzed. The prenatal, perinatal, and postnatal exposure to organophosphate, organochlorine, pyrethroid, neonicotinoid, and carbamate, as well as a combined pesticide exposure was reviewed. This systematic review reveals that the effects of pesticide exposure on body weight are mostly inconclusive, finding conflicting results in both humans and experimental animals. The outcomes reviewed are dependent on many factors, including dosage and route of administration, species, sex, and treatment duration. More research is needed to effectively evaluate the impact of the combined effects of different pesticides on human health.

scholarly journals Adult NG2-Glia Are Required for Median Eminence-Mediated Leptin Sensing and Body Weight Control

2016 ◽  
Vol 23 (5) ◽  
pp. 797-810 ◽  
Author(s):  
Tina Djogo ◽  
Sarah C. Robins ◽  
Sarah Schneider ◽  
Darya Kryzskaya ◽  
Xiaohong Liu ◽  
...  
Keyword(s):  
Body Weight ◽  
Median Eminence ◽  
Weight Control ◽  
Body Weight Control

Disturbed Body Weight Control in Geriatric Rats: a Model for Anorexia in Alzheimers

1992 ◽  
pp. 451-459
Author(s):  
Collin R. Park ◽  
Sabine M. von Preyss-Friedman ◽  
Robert S. Schwartz ◽  
Stephen C. Woods
Keyword(s):  
Body Weight ◽  
Weight Control ◽  
Body Weight Control
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