Mitochondrial encephalomyopathy with lactic acidosis and stroke like episodes (MELAS) with prominent degeneration of the intestinal wall and cactus-like cerebellar pathology

2000 ◽  
Vol 100 (6) ◽  
pp. 712-717 ◽  
Author(s):  
O. Mori ◽  
Mineo Yamazaki ◽  
Yoshiharu Ohaki ◽  
Yasushi Arai ◽  
Tatsuo Oguro ◽  
...  
Keyword(s):  
Lactic Acidosis ◽  
Intestinal Wall ◽  
Mitochondrial Encephalomyopathy

scholarly journals General anesthesia with remimazolam in a patient with mitochondrial encephalomyopathy: a case report

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Yuji Suzuki ◽  
Matsuyuki Doi ◽  
Yoshiki Nakajima
Keyword(s):  
Lactic Acidosis ◽  
General Anesthesia ◽  
Mitochondrial Disease ◽  
Muscle Relaxation ◽  
Anesthetic Management ◽  
Perioperative Period ◽  
Mitochondrial Encephalomyopathy ◽  
Anesthesia Induction ◽  
General Anesthetic ◽  
Anesthetic Agents

Abstract Background Systemic anesthetic management of patients with mitochondrial disease requires careful preoperative preparation to administer adequate anesthesia and address potential disease-related complications. The appropriate general anesthetic agents to use in these patients remain controversial. Case presentation A 54-year-old woman (height, 145 cm; weight, 43 kg) diagnosed with mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes underwent elective cochlear implantation. Infusions of intravenous remimazolam and remifentanil guided by patient state index monitoring were used for anesthesia induction and maintenance. Neither lactic acidosis nor prolonged muscle relaxation occurred in the perioperative period. At the end of surgery, flumazenil was administered to antagonize sedation, which rapidly resulted in consciousness. Conclusions Remimazolam administration and reversal with flumazenil were successfully used for general anesthesia in a patient with mitochondrial disease.

Episodic Hyponatremia in Mitochondrial Encephalomyopathy, Lactic Acidosis, and Strokelike Episodes (MELAS)

2005 ◽  
Vol 20 (2) ◽  
pp. 116-119 ◽  
Author(s):  
Hiroaki Kubota ◽  
Yuzo Tanabe ◽  
Jun-ichi Takanashi ◽  
Yoichi Kohno
Keyword(s):  
Lactic Acidosis ◽  
Mitochondrial Encephalomyopathy

scholarly journals A Novel Mutation in the Mitochondrial DNA CytochromebGene (MTCYB)in a Patient With Mitochondrial Encephalomyopathy, Lactic Acidosis, and Strokelike Episodes Syndrome

2012 ◽  
Vol 28 (2) ◽  
pp. 236-242 ◽  
Author(s):  
Valentina Emmanuele ◽  
Evangelia Sotiriou ◽  
Purificación Gutierrez Rios ◽  
Jaya Ganesh ◽  
Rebecca Ichord ◽  
...  
Keyword(s):  
Mitochondrial Dna ◽  
Lactic Acidosis ◽  
Novel Mutation ◽  
Mitochondrial Encephalomyopathy
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