Adiponectin negatively regulates pigmentation, Wnt/β-catenin and HGF/c-Met signalling within human scalp hair follicles ex vivo

2021 ◽  
Author(s):  
Carina Nicu ◽  
Jennifer Jackson ◽  
Asim Shahmalak ◽  
Jenny Pople ◽  
David Ansell ◽  
...  
Keyword(s):  
Scalp Hair ◽  
Ex Vivo ◽  
Hair Follicles ◽  
Human Scalp Hair

scholarly journals Human Scalp Hair Follicles Are Both a Target and a Source of Prolactin, which Serves as an Autocrine and/or Paracrine Promoter of Apoptosis-Driven Hair Follicle Regression

2006 ◽  
Vol 168 (3) ◽  
pp. 748-756 ◽  
Author(s):  
Kerstin Foitzik ◽  
Karoline Krause ◽  
Franziska Conrad ◽  
Motonobu Nakamura ◽  
Wolfang Funk ◽  
...  
Keyword(s):  
Hair Follicle ◽  
Scalp Hair ◽  
Hair Follicles ◽  
Human Scalp Hair

scholarly journals Discrimination of Acne Vulgaris with Human Scalp Hair Tissues Using - FTIR-ATR Spectroscopy

2019 ◽  
Author(s):  
Padmavathi R ◽  
Gunasekaran S ◽  
Rajamannan B ◽  
Ramkumar GR ◽  
Sankari G ◽  
...  
Keyword(s):  
Scalp Hair ◽  
Acne Vulgaris ◽  
Hair Follicles ◽  
Pilosebaceous Unit ◽  
Tissue Samples ◽  
Spectral Signatures ◽  
Human Scalp Hair ◽  
Chronic Skin ◽  
Noninvasive Sample ◽  
Atr Spectroscopy

Acne vulgaris is a chronic skin disease which occurs due to inflammation of the hair follicles and sebum-producing (sebaceous) glands of the skin called pilosebaceous unit and the anaerobic propionic acne bacterium, P.acne. Human sebum is dominantly made up of 57.5% of triglycerides and fatty acids, 26%wax esters, 12% Squalene and 4.5% Cholesterol. The increased level Androgen hormone, sebum lipid composition, P.acne overgrowth which induces monocytes and pro-inflammatory cytokines attract neutrophils, basophils, and T cells to the pilosebaceous unit and drive epithelial hyperproliferation i.e., Acne vulgaris. The actual biomolecular changes due to acne vulgaris disease are present in the blood and in the sebum and also in the noninvasive sample of human scalp hair follicles. The main objectives of the present study are to analyze human scalp hair follicles samples using FTIR-ATR spectroscopy to compare and discriminate the spectral signatures of acne vulgaris and healthy scalp hair tissue samples through acne bio-markers Protein, Amide I, Amide II and Squalene (LDL), using the method of internal ratio parameters.

Evidence for Alpha-MSH Binding Sites on Human Scalp Hair Follicles: Preliminary Results

1991 ◽  
Vol 4 (4) ◽  
pp. 193-198 ◽  
Author(s):  
P.B. NANNINGA ◽  
G.E. GHANEM ◽  
F.J. LEJEUNE ◽  
J.D. BOS ◽  
W. WESTERHOF
Keyword(s):  
Binding Sites ◽  
Scalp Hair ◽  
Hair Follicles ◽  
Preliminary Results ◽  
Human Scalp Hair

scholarly journals Identifying novel strategies for treating human hair loss disorders: Cyclosporine A suppresses the Wnt inhibitor, SFRP1, in the dermal papilla of human scalp hair follicles

PLoS Biology ◽  
2018 ◽  
Vol 16 (5) ◽  
pp. e2003705 ◽  
Author(s):  
Nathan J. Hawkshaw ◽  
Jonathan A. Hardman ◽  
Iain S. Haslam ◽  
Asim Shahmalak ◽  
Amos Gilhar ◽  
...  
Keyword(s):  
Hair Loss ◽  
Cyclosporine A ◽  
Human Hair ◽  
Scalp Hair ◽  
Dermal Papilla ◽  
Hair Follicles ◽  
Human Scalp Hair ◽  
Wnt Inhibitor

Protein biosynthesis in isolated human scalp hair follicles

1978 ◽  
Vol 4 (4) ◽  
pp. 211-216 ◽  
Author(s):  
A. J. M. Vermorken ◽  
P. J. J. M. Weterings ◽  
H. Bloemendal
Keyword(s):  
Scalp Hair ◽  
Protein Biosynthesis ◽  
Hair Follicles ◽  
Human Scalp Hair

scholarly journals Simple and rapid method to isolate and culture follicular papillae from human scalp hair follicles

2002 ◽  
Vol 11 (4) ◽  
pp. 381-385 ◽  
Author(s):  
Markus Magerl ◽  
Sobia Kauser ◽  
Ralf Paus ◽  
Desmond J. Tobin
Keyword(s):  
Rapid Method ◽  
Scalp Hair ◽  
Hair Follicles ◽  
Human Scalp Hair

scholarly journals Discrimination of Acne Vulgaris with Human Scalp Hair Tissues Using FTIR-ATR Spectroscopy

2020 ◽  
Author(s):  
Padmavathi Ramanujam ◽  
Rajamannan B ◽  
Gunasekaran S ◽  
Ramkumar GR ◽  
Sankari G ◽  
...  
Keyword(s):  
Scalp Hair ◽  
Acne Vulgaris ◽  
Hair Follicles ◽  
Pilosebaceous Unit ◽  
Spectral Signatures ◽  
Human Scalp Hair ◽  
Hair Samples ◽  
Chronic Skin ◽  
Noninvasive Sample ◽  
Atr Spectroscopy

Acne vulgaris is a chronic skin disease, which occurs due to inflammation of the hair follicles and sebum-producing (sebaceous) glands of the skin called pilosebaceous unit and the anaerobic propionic acne bacterium, P. Acne. Human sebum is dominantly made up of about 57.5% of triglycerides and fatty acids, 26%wax esters, 12% Squalene, and 4.5% Cholesterol. The increased level Androgen hormone, sebum lipid composition, P. Acne overgrowth which induces monocytes and pro-inflammatory cytokines attract neutrophils, basophils, and T cells to the pilosebaceous unit and drive epithelial hyperproliferation i.e., Acne vulgaris. The actual Biomolecular changes due to acne vulgaris disease are present in the blood, in the sebum, and in the noninvasive sample of human scalp hair follicles. The main objectives of the present study are to analyze human scalp hair follicles samples using FTIR-ATR spectroscopy to compare and discriminate the spectral signatures of acne vulgaris and healthy scalp hair samples through acne biomarkers Protein, Amide I, Amide II and Squalene (LDL), using the method of internal ratio parameters.

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