First trimester pregnancy volumes and subsequent small for gestational age fetuses

Introduction: The earliest proof of a viable pregnancy is obtained when cardiac activity of the embryo can be observed. Transvaginal sonography can accurately demonstrate embryonic heart rate at 6 weeks of gestational age by using M-mode transvaginal sonography. Slow embryonic heart rate at 6-7 weeks of gestational age is associated with high rate of first trimester pregnancy loss. AIM: The study was aimed to evaluate the role of embryonic heart rate (EHR) of early pregnancies as predictive factor of adverse outcome at end of first trimester of pregnancy. Methods: This observational study was conducted in the Department of Obstetrics and Gynecology Zenana Hospital, SMS Medical College, Jaipur. It included 300 pregnant women between 6 weeks to 9 weeks of gestational age attending antenatal OPD. Embryonic heart rate was measured by transvaginal sonography. Embryonic heart rate was classified as slow, if it was fewer than 110 beats/ mint or outcome was measured as occurance of spontaneous pregnancy loss prior to 12 weeks. Results: Out of 300 cases, 290 (96.67%) had embryonic heart rate ?100 beats per minutes and 10(3.33%) had embryonic heart rate <100 beats per minutes. Out of these 290, (Embryonic heart rate ?100 beats per minutes), 284 (97.93%) had good prognosis and 6 (2.07%) had abortion. In 10 women (Embryonic heart rate <100 beats per minutes), 3 (30.00%) had good prognosis and 7 (70.00%) had abortion. This observation was statistically significant. Conclusion: Slow embryonic heart rate on ultrasonography reduced the success of pregnancy and may lead to abortion. Keywords: Embryonic heart rate, Ultrasonography, Early pregnancy loss

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The Retrospective Analysis on the Influence of Taking Mifepristone and Misoprostol During First-trimester Pregnancy and Its Following Impact on Tissue Residual After Induced Abortion

10.21203/rs.3.rs-569024/v1 ◽

2021 ◽

Author(s):

Hai Xia xie ◽

Xiao Li Liu ◽

Jun Jie Sun ◽

Jian Rong Huang

Keyword(s):

Gestational Age ◽

Uterine Cavity ◽

Test Group ◽

First Trimester ◽

Induced Abortion ◽

Control Group ◽

First Trimester Pregnancy ◽

Trimester Pregnancy ◽

Women And Children ◽

Residual Tissue

Abstract Objective: To explore the application of mifepristone in the stream of Residual tissue after abortion . Methods: A retrospective study of 1067 women who selected induced abortion in first-trimester pregnancy(gestational age ≤ 70 days) between January 1st，2018 and May 31st，2019 in Chongqing Health Center For Women and Children . Inclusion criteria: the first pregnancy patients, aged 18-30 years, gestational age ≤ 70 days. Test group (mifepristone + misoprostol) 467 cases. Control group(misoprostol) 600 cases. Analyzing the incidence of residual tissue after induced abortion. Evaluating the preventive effect of preoperative oral mifepristone on abortion incompleteness. Results: a total of 9 in test group occur residual tissue in uterine cavity，the incidence is 1.93%. In the controlled group, the number of residual tissue is 25,the incidence is 4.16%(P<0.05)，there was statistic difference between two groups. The uterine residue diameter in the test group(1.1±0.31cm) was lower than that in the control group(1.24±0.64cm)，but there was no statistical difference between the two groups of residue diameter (P>0.05)Conclusion: Oral mifepristone before operation can significantly reduce the incidence of tissue residual after induced abortion.

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Yolk sac diameter as a prognostic factor for first trimester pregnancy outcome

Nepal Journal of Obstetrics and Gynaecology ◽

10.3126/njog.v15i1.29339 ◽

2020 ◽

Vol 15 (1) ◽

pp. 39-42

Author(s):

Anupama Bhattarai ◽

Gehanath Baral

Keyword(s):

Prognostic Factor ◽

Positive Predictive Value ◽

Pregnancy Outcome ◽

Gestational Age ◽

Predictive Value ◽

First Trimester ◽

Yolk Sac ◽

Abnormal Pregnancy ◽

First Trimester Pregnancy ◽

Trimester Pregnancy

Aims: To evaluate yolk sac diameter as a predictor of first trimester pregnancy outcome. Methods: This was a prospective observational study conducted at Paropakar Maternity and Women’s Hospital from October 2017 to October 2018. Pregnant women in between seven and ten weeks of gestation were enrolled. Transabdominal sonography was performed to measure yolk sac diameter and followed up till 12 weeks of gestation to see the outcome. Sensitivity, specificity, positive predictive value and negative predictive value were calculated for yolk sac diameter with regards to abnormal pregnancy outcome. Results: There were 80 cases enrolled and a significant positive correlation was found between yolk sac diameter and gestational age. Abnormal yolk sac diameter, irrespective of gestational age, had sensitivity of 92.95%, specificity 66.66%, positive predictive value 95.6% and negative predictive value of 54.54% in predicting abnormal pregnancy outcome. Conclusions: The measurement of yolk sac diameter between seventh and tenth weeks of gestation can predict first trimester pregnancy outcome. This is useful while counseling pregnant women regarding risk of abnormal outcome and need for follow up ultrasonography. Keywords: first trimester; pregnancy outcome; prognostic factor; yolk sac diameter

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SUCCESSFUL MANAGEMENT OF OVARIAN CYST TORSION DURING FIRST TRIMESTER PREGNANCY: A CASE REPORT

10.36106/gjra/0705461 ◽

2020 ◽

pp. 17-18

Author(s):

Vijaya Gopulwad ◽

Shirish Toshniwal ◽

Pravin Jadav

Keyword(s):

Gestational Age ◽

Ovarian Cyst ◽

Surgical Intervention ◽

Acute Abdominal Pain ◽

Adnexal Mass ◽

First Trimester ◽

First Trimester Pregnancy ◽

Pain Abdomen ◽

Trimester Pregnancy

Adnexal torsion is an unusual cause of acute abdominal pain during pregnancy. In this case we report a 22 –year old primigravida with 7 weeks gestational age presenting with partial torsion of the left ovarian cyst. She presented to emergency department with acute pain abdomen. She was diagnosed to have partial torsion of left ovarian cyst during pregnancy and oophoropexy was done. Her pregnancy is being followed up and she is currently at 9 weeks of gestation. Although the safety of antepartum surgical intervention has been accepted, abdominal surgery nevertheless carries some risks to a pregnant woman and unborn foetus, and so the choice of management necessitates a weighing of risks based on characterization of the adnexal mass and gestational age.

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Accuracy of emergency physician performed bedside ultrasound in determining gestational age in first trimester pregnancy

Critical Ultrasound Journal ◽

10.1186/2036-7902-4-22 ◽

2012 ◽

Vol 4 (1) ◽

Cited By ~ 4

Author(s):

Turandot Saul ◽

Resa E Lewiss ◽

Marina Del Rios Rivera

Keyword(s):

Gestational Age ◽

Emergency Physician ◽

First Trimester ◽

Bedside Ultrasound ◽

First Trimester Pregnancy ◽

Trimester Pregnancy

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Efficacy of combination of tablet mifepristone and misoprostol for first trimester pregnancy termination at different gestational age

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20175855 ◽

2017 ◽

Vol 7 (1) ◽

pp. 248

Author(s):

Poonam Bhojwani ◽

Pragati Meena ◽

Gajendra Singh Verma

Keyword(s):

Side Effects ◽

Gestational Age ◽

Pregnancy Termination ◽

First Trimester ◽

P Value ◽

First Trimester Pregnancy ◽

Trimester Pregnancy ◽

Group A ◽

The Difference ◽

Group B

Background: Medical method of abortion is a safe, effective and affordable method for first trimester termination. However, nausea, vomiting, diarhoea, excess bleeding and incomplete abortion are known side effects. The aim of study was to compare the success rate of abortions in both groups, to compare the induction-abortion interval in both groups and to study the side effects of the drugs.Methods: This study was conducted in department of obstetrics and gynecology, NIMS Medical College, Jaipur, India during June 2017-August 2017. Total hundred cases were taken and divided into two groups. Group A was gestational age upto 49 days, Group B was gestational age 50-63 days. Both groups were given tab. mifepristone 200mg. followed by 48 hrs. by 4 tablets of tab misoprostol.Results: The results of the given regimen were highly successful and complete abortion was achieved in 96% and 94% in group A and group B respectively. The difference between two groups was statistically not significant (p value =0.64). Failure rates were seen in only 4% of group A and 6% of group B. Pain abdomen was seen in 16% of group A and 38% of group B patients. The difference between both groups was statistically significant (p value=0.02). Nausea was seen in 10% of group A and 30% of group B patients. The difference between both groups is statistically significant(p value=0.018).Conclusions: First trimester pregnancy can be successfully terminated with combination of mifepristone and misoprostol upto 63 days (9 weeks) of pregnancy.

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